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Bromine in PDB 7rwh: Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998Enzymatic activity of Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998
All present enzymatic activity of Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998:
2.5.1.6; Protein crystallography data
The structure of Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998, PDB code: 7rwh
was solved by
L.Jin,
A.K.Padyana,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7rwh:
The structure of Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998 also contains other interesting chemical elements:
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998
(pdb code 7rwh). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998, PDB code: 7rwh: Bromine binding site 1 out of 1 in 7rwhGo back to Bromine Binding Sites List in 7rwh
Bromine binding site 1 out
of 1 in the Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998
Mono view Stereo pair view
Reference:
M.Li,
Z.Konteatis,
N.Nagaraja,
Y.Chen,
S.Zhou,
G.Ma,
S.Gross,
K.Marjon,
M.L.Hyer,
E.Mandley,
M.Lein,
A.K.Padyana,
L.Jin,
S.Tong,
R.Peters,
J.Murtie,
J.Travins,
M.Medeiros,
P.Liu,
V.Frank,
E.T.Judd,
S.A.Biller,
K.M.Marks,
Z.Sui,
S.K.Reznik.
Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. J.Med.Chem. V. 65 4600 2022.
Page generated: Thu Jul 11 04:32:02 2024
ISSN: ISSN 0022-2623 PubMed: 35293760 DOI: 10.1021/ACS.JMEDCHEM.1C01595 |
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