Bromine in PDB 7s3b: Crystal Structure of Intact U2AF65 Rrm-Region Bound to Adml-G5 Oligonucleotide

The structure of Crystal Structure of Intact U2AF65 Rrm-Region Bound to Adml-G5 Oligonucleotide, PDB code: 7s3b was solved by J.L.Jenkins, S.Henderson, C.L.Kielkopf, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.85 / 1.89
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	43.668, 57.839, 76.938, 90, 90, 90
R / Rfree (%)	17.3 / 20

The binding sites of Bromine atom in the Crystal Structure of Intact U2AF65 Rrm-Region Bound to Adml-G5 Oligonucleotide (pdb code 7s3b). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of Intact U2AF65 Rrm-Region Bound to Adml-G5 Oligonucleotide, PDB code: 7s3b:

Bromine binding site 1 out of 1 in the Crystal Structure of Intact U2AF65 Rrm-Region Bound to Adml-G5 Oligonucleotide


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of Intact U2AF65 Rrm-Region Bound to Adml-G5 Oligonucleotide within 5.0Å range: probe atom residue distance (Å) B Occ B:Br7 b:88.5 occ:1.00 BR B:BRU7 0.0 88.5 1.0 C5 B:BRU7 1.9 19.3 1.0 C6 B:BRU7 2.9 18.7 1.0 H6 B:BRU7 3.0 22.4 1.0 C4 B:BRU7 3.0 15.3 1.0 O4 B:BRU7 3.2 18.6 1.0 HZ3 A:LYS225 3.2 43.2 1.0 O A:HOH593 3.3 28.5 1.0 CE1 A:TYR152 3.5 19.7 1.0 HE1 A:TYR152 3.5 23.6 1.0 HH A:TYR152 3.5 26.5 1.0 CZ A:TYR152 3.6 19.1 1.0 OP2 B:U6 3.7 56.8 1.0 OH A:TYR152 3.8 22.1 1.0 H3' B:U6 3.9 40.5 1.0 HE2 A:LYS225 3.9 30.3 1.0 NZ A:LYS225 4.0 36.0 1.0 CD1 A:TYR152 4.0 17.3 1.0 HZ1 A:LYS225 4.1 43.2 1.0 O5' B:U6 4.1 58.5 1.0 N1 B:BRU7 4.1 18.0 1.0 HG3 A:ARG227 4.1 14.7 1.0 N3 B:BRU7 4.2 16.2 1.0 CE2 A:TYR152 4.3 19.0 1.0 O B:HOH116 4.3 28.1 1.0 HD1 A:TYR152 4.3 20.7 1.0 HD3 A:LYS225 4.3 21.7 1.0 CE A:LYS225 4.4 25.3 1.0 HE1 A:HIS230 4.4 22.9 1.0 NE2 A:HIS230 4.5 19.4 1.0 O A:HOH507 4.5 30.4 1.0 P B:U6 4.6 71.5 1.0 CG A:TYR152 4.6 14.6 1.0 HZ2 A:LYS225 4.7 43.2 1.0 C2 B:BRU7 4.7 16.5 1.0 CD2 A:TYR152 4.7 18.1 1.0 CE1 A:HIS230 4.7 19.1 1.0 HE2 A:TYR152 4.7 22.8 1.0 H2' B:U6 4.8 43.0 1.0 C3' B:U6 4.8 33.8 1.0 O A:HOH535 4.8 35.3 1.0 HB2 A:ARG227 4.9 15.0 1.0 O5' B:BRU7 4.9 35.5 1.0 H5' B:U6 4.9 49.0 1.0 CD A:LYS225 4.9 18.1 1.0

E.Glasser, D.Maji, G.Biancon, A.M.K.Puthenpeedikakkal, C.E.Cavender, T.Tebaldi, J.L.Jenkins, D.H.Mathews, S.Halene, C.L.Kielkopf. Pre-Mrna Splicing Factor U2AF2 Recognizes Distinct Conformations of Nucleotide Variants at the Center of the Pre-Mrna Splice Site Signal. Nucleic Acids Res. V. 50 5299 2022.
ISSN: ESSN 1362-4962
PubMed: 35524551
DOI: 10.1093/NAR/GKAC287