Bromine in PDB 7uw0: Crystal Structure of Human Clpp Protease in Complex with Tr-133
Enzymatic activity of Crystal Structure of Human Clpp Protease in Complex with Tr-133
All present enzymatic activity of Crystal Structure of Human Clpp Protease in Complex with Tr-133:
3.4.21.92;
3.4.21.92;
Protein crystallography data
The structure of Crystal Structure of Human Clpp Protease in Complex with Tr-133, PDB code: 7uw0
was solved by
M.F.Mabanglo,
W.A.Houry,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 51.69 / 2.80 |
| Space group | I 1 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 105.66, 153.798, 133.208, 90, 107.03, 90 |
| R / Rfree (%) | 26 / 30.9 |
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of Human Clpp Protease in Complex with Tr-133
(pdb code 7uw0). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total 7 binding sites of Bromine where determined in the Crystal Structure of Human Clpp Protease in Complex with Tr-133, PDB code: 7uw0:
Jump to Bromine binding site number: 1; 2; 3; 4; 5; 6; 7;
In total 7 binding sites of Bromine where determined in the Crystal Structure of Human Clpp Protease in Complex with Tr-133, PDB code: 7uw0:
Jump to Bromine binding site number: 1; 2; 3; 4; 5; 6; 7;
Bromine binding site 1 out of 7 in 7uw0
Go back to
Bromine Binding Sites List in 7uw0
Bromine binding site 1 out
of 7 in the Crystal Structure of Human Clpp Protease in Complex with Tr-133
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 1 of Crystal Structure of Human Clpp Protease in Complex with Tr-133 within 5.0Å range:
|
Bromine binding site 2 out of 7 in 7uw0
Go back to
Bromine Binding Sites List in 7uw0
Bromine binding site 2 out
of 7 in the Crystal Structure of Human Clpp Protease in Complex with Tr-133
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 2 of Crystal Structure of Human Clpp Protease in Complex with Tr-133 within 5.0Å range:
|
Bromine binding site 3 out of 7 in 7uw0
Go back to
Bromine Binding Sites List in 7uw0
Bromine binding site 3 out
of 7 in the Crystal Structure of Human Clpp Protease in Complex with Tr-133
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 3 of Crystal Structure of Human Clpp Protease in Complex with Tr-133 within 5.0Å range:
|
Bromine binding site 4 out of 7 in 7uw0
Go back to
Bromine Binding Sites List in 7uw0
Bromine binding site 4 out
of 7 in the Crystal Structure of Human Clpp Protease in Complex with Tr-133
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 4 of Crystal Structure of Human Clpp Protease in Complex with Tr-133 within 5.0Å range:
|
Bromine binding site 5 out of 7 in 7uw0
Go back to
Bromine Binding Sites List in 7uw0
Bromine binding site 5 out
of 7 in the Crystal Structure of Human Clpp Protease in Complex with Tr-133
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 5 of Crystal Structure of Human Clpp Protease in Complex with Tr-133 within 5.0Å range:
|
Bromine binding site 6 out of 7 in 7uw0
Go back to
Bromine Binding Sites List in 7uw0
Bromine binding site 6 out
of 7 in the Crystal Structure of Human Clpp Protease in Complex with Tr-133
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 6 of Crystal Structure of Human Clpp Protease in Complex with Tr-133 within 5.0Å range:
|
Bromine binding site 7 out of 7 in 7uw0
Go back to
Bromine Binding Sites List in 7uw0
Bromine binding site 7 out
of 7 in the Crystal Structure of Human Clpp Protease in Complex with Tr-133
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 7 of Crystal Structure of Human Clpp Protease in Complex with Tr-133 within 5.0Å range:
|
Reference:
M.F.Mabanglo,
K.S.Wong,
M.M.Barghash,
E.Leung,
S.H.W.Chuang,
A.Ardalan,
E.M.Majaesic,
C.J.Wong,
S.Zhang,
H.Lang,
D.S.Karanewsky,
A.A.Iwanowicz,
L.M.Graves,
E.J.Iwanowicz,
A.C.Gingras,
W.A.Houry.
Potent Clpp Agonists with Anticancer Properties Bind with Improved Structural Complementarity and Alter the Mitochondrial N-Terminome. Structure 2022.
ISSN: ISSN 0969-2126
PubMed: 36586405
DOI: 10.1016/J.STR.2022.12.002
Page generated: Tue Apr 4 17:40:25 2023
ISSN: ISSN 0969-2126
PubMed: 36586405
DOI: 10.1016/J.STR.2022.12.002
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