Bromine in PDB 7vp9: Crystal Structure of Human Clpp in Complex with ZG111
Enzymatic activity of Crystal Structure of Human Clpp in Complex with ZG111
All present enzymatic activity of Crystal Structure of Human Clpp in Complex with ZG111:
3.4.21.92;
Protein crystallography data
The structure of Crystal Structure of Human Clpp in Complex with ZG111, PDB code: 7vp9
was solved by
P.Y.Wang,
J.H.Gan,
C.-G.Yang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
28.84 /
2.55
|
Space group
|
P 1 21 1
|
Cell size a, b, c (Å), α, β, γ (°)
|
103.806,
97.408,
146.686,
90,
90.63,
90
|
R / Rfree (%)
|
20.2 /
23.2
|
Other elements in 7vp9:
The structure of Crystal Structure of Human Clpp in Complex with ZG111 also contains other interesting chemical elements:
Bromine Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
14;
Binding sites:
The binding sites of Bromine atom in the Crystal Structure of Human Clpp in Complex with ZG111
(pdb code 7vp9). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total 14 binding sites of Bromine where determined in the
Crystal Structure of Human Clpp in Complex with ZG111, PDB code: 7vp9:
Jump to Bromine binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Bromine binding site 1 out
of 14 in 7vp9
Go back to
Bromine Binding Sites List in 7vp9
Bromine binding site 1 out
of 14 in the Crystal Structure of Human Clpp in Complex with ZG111
Mono view
Stereo pair view
|
A full contact list of Bromine with other atoms in the Br binding
site number 1 of Crystal Structure of Human Clpp in Complex with ZG111 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Br301
b:97.9
occ:1.00
|
BR1
|
A:7SR301
|
0.0
|
97.9
|
1.0
|
C39
|
A:7SR301
|
2.0
|
87.2
|
1.0
|
C38
|
A:7SR301
|
2.9
|
83.8
|
1.0
|
C41
|
A:7SR301
|
2.9
|
84.7
|
1.0
|
CD1
|
A:ILE75
|
3.3
|
75.6
|
1.0
|
CG
|
A:ARG78
|
3.7
|
78.7
|
1.0
|
O
|
A:ILE75
|
3.7
|
55.6
|
1.0
|
CB
|
G:PHE105
|
3.8
|
62.7
|
1.0
|
CG
|
A:LEU79
|
3.9
|
69.2
|
1.0
|
CG1
|
A:ILE75
|
3.9
|
72.0
|
1.0
|
N
|
A:LEU79
|
3.9
|
75.2
|
1.0
|
CB
|
A:ARG78
|
4.0
|
79.2
|
1.0
|
O
|
G:ALA101
|
4.1
|
61.0
|
1.0
|
C37
|
A:7SR301
|
4.2
|
81.6
|
1.0
|
C42
|
A:7SR301
|
4.2
|
83.0
|
1.0
|
CA
|
A:LEU79
|
4.2
|
72.5
|
1.0
|
C
|
A:ARG78
|
4.3
|
75.1
|
1.0
|
CD2
|
A:LEU79
|
4.3
|
68.6
|
1.0
|
CG
|
G:PHE105
|
4.4
|
72.2
|
1.0
|
CD1
|
G:PHE105
|
4.4
|
79.5
|
1.0
|
CB
|
A:LEU79
|
4.5
|
72.2
|
1.0
|
CA
|
G:PHE105
|
4.5
|
64.5
|
1.0
|
C
|
A:ILE75
|
4.7
|
66.1
|
1.0
|
O
|
A:ARG78
|
4.7
|
75.4
|
1.0
|
C36
|
A:7SR301
|
4.7
|
81.1
|
1.0
|
CA
|
A:ARG78
|
4.8
|
76.9
|
1.0
|
N
|
G:PHE105
|
4.8
|
65.9
|
1.0
|
C
|
G:ALA101
|
4.9
|
63.0
|
1.0
|
CA
|
A:ILE75
|
4.9
|
76.9
|
1.0
|
CD1
|
A:LEU79
|
4.9
|
66.7
|
1.0
|
|
Bromine binding site 2 out
of 14 in 7vp9
Go back to
Bromine Binding Sites List in 7vp9
Bromine binding site 2 out
of 14 in the Crystal Structure of Human Clpp in Complex with ZG111
Mono view
Stereo pair view
|
A full contact list of Bromine with other atoms in the Br binding
site number 2 of Crystal Structure of Human Clpp in Complex with ZG111 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Br302
b:114.8
occ:1.00
|
BR1
|
A:7SR302
|
0.0
|
114.8
|
1.0
|
C39
|
A:7SR302
|
2.0
|
112.7
|
1.0
|
C41
|
A:7SR302
|
2.9
|
111.9
|
1.0
|
C38
|
A:7SR302
|
2.9
|
112.5
|
1.0
|
CD1
|
B:LEU79
|
3.3
|
80.2
|
1.0
|
CB
|
A:PHE105
|
3.3
|
80.1
|
1.0
|
N
|
B:LEU79
|
3.8
|
76.3
|
1.0
|
CG
|
B:ARG78
|
3.8
|
72.7
|
1.0
|
CB
|
B:LEU79
|
3.8
|
75.2
|
1.0
|
CA
|
B:LEU79
|
3.8
|
76.3
|
1.0
|
O
|
B:ILE75
|
3.8
|
65.5
|
1.0
|
CG
|
B:LEU79
|
3.8
|
77.2
|
1.0
|
CG1
|
B:ILE75
|
3.8
|
74.7
|
1.0
|
CD1
|
A:PHE105
|
3.9
|
88.7
|
1.0
|
O
|
A:ALA101
|
4.0
|
65.8
|
1.0
|
CG
|
A:PHE105
|
4.0
|
84.1
|
1.0
|
CA
|
A:PHE105
|
4.1
|
76.2
|
1.0
|
C
|
B:ARG78
|
4.2
|
77.6
|
1.0
|
C42
|
A:7SR302
|
4.2
|
112.3
|
1.0
|
C37
|
A:7SR302
|
4.2
|
111.9
|
1.0
|
CB
|
B:ARG78
|
4.2
|
75.1
|
1.0
|
N
|
A:PHE105
|
4.4
|
74.2
|
1.0
|
CD1
|
B:ILE75
|
4.4
|
76.2
|
1.0
|
O
|
B:ARG78
|
4.5
|
78.4
|
1.0
|
C36
|
A:7SR302
|
4.7
|
112.1
|
1.0
|
C
|
B:ILE75
|
4.8
|
69.8
|
1.0
|
CA
|
B:ARG78
|
4.9
|
78.2
|
1.0
|
C
|
A:ALA101
|
4.9
|
66.6
|
1.0
|
CE1
|
A:PHE105
|
5.0
|
89.6
|
1.0
|
|
Bromine binding site 3 out
of 14 in 7vp9
Go back to
Bromine Binding Sites List in 7vp9
Bromine binding site 3 out
of 14 in the Crystal Structure of Human Clpp in Complex with ZG111
Mono view
Stereo pair view
|
A full contact list of Bromine with other atoms in the Br binding
site number 3 of Crystal Structure of Human Clpp in Complex with ZG111 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Br301
b:107.9
occ:1.00
|
BR1
|
B:7SR301
|
0.0
|
107.9
|
1.0
|
C39
|
B:7SR301
|
1.9
|
101.7
|
1.0
|
C41
|
B:7SR301
|
2.8
|
99.4
|
1.0
|
C38
|
B:7SR301
|
2.8
|
98.7
|
1.0
|
CB
|
B:PHE105
|
3.6
|
79.0
|
1.0
|
CD1
|
C:ILE75
|
3.9
|
69.7
|
1.0
|
O
|
C:ILE75
|
4.0
|
79.4
|
1.0
|
N
|
C:LEU79
|
4.0
|
90.7
|
1.0
|
C42
|
B:7SR301
|
4.1
|
98.1
|
1.0
|
CD1
|
B:PHE105
|
4.1
|
73.4
|
1.0
|
C37
|
B:7SR301
|
4.1
|
96.7
|
1.0
|
O
|
B:ALA101
|
4.1
|
77.8
|
1.0
|
CA
|
B:PHE105
|
4.1
|
82.9
|
1.0
|
CG
|
B:PHE105
|
4.2
|
74.8
|
1.0
|
CB
|
C:ARG78
|
4.2
|
76.2
|
1.0
|
C
|
C:ARG78
|
4.3
|
86.7
|
1.0
|
CA
|
C:LEU79
|
4.3
|
88.7
|
1.0
|
CG1
|
C:ILE75
|
4.4
|
73.9
|
1.0
|
N
|
B:PHE105
|
4.5
|
83.4
|
1.0
|
C36
|
B:7SR301
|
4.5
|
96.1
|
1.0
|
CB
|
C:LEU79
|
4.5
|
85.0
|
1.0
|
O
|
C:ARG78
|
4.6
|
92.2
|
1.0
|
CA
|
C:ARG78
|
4.9
|
84.8
|
1.0
|
C
|
C:ILE75
|
5.0
|
80.9
|
1.0
|
|
Bromine binding site 4 out
of 14 in 7vp9
Go back to
Bromine Binding Sites List in 7vp9
Bromine binding site 4 out
of 14 in the Crystal Structure of Human Clpp in Complex with ZG111
Mono view
Stereo pair view
|
A full contact list of Bromine with other atoms in the Br binding
site number 4 of Crystal Structure of Human Clpp in Complex with ZG111 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Br301
b:100.8
occ:1.00
|
BR1
|
D:7SR301
|
0.0
|
100.8
|
1.0
|
C39
|
D:7SR301
|
1.9
|
102.9
|
1.0
|
C41
|
D:7SR301
|
2.8
|
104.1
|
1.0
|
C38
|
D:7SR301
|
2.9
|
104.2
|
1.0
|
CG1
|
E:ILE75
|
3.5
|
92.4
|
1.0
|
O
|
E:ILE75
|
3.6
|
87.7
|
1.0
|
CG
|
E:ARG78
|
3.6
|
99.2
|
1.0
|
CB
|
D:PHE105
|
3.6
|
94.0
|
1.0
|
CB
|
E:ARG78
|
3.9
|
95.9
|
1.0
|
N
|
E:LEU79
|
4.0
|
93.3
|
1.0
|
O
|
D:ALA101
|
4.0
|
89.8
|
1.0
|
C42
|
D:7SR301
|
4.1
|
106.1
|
1.0
|
CD1
|
E:ILE75
|
4.2
|
94.2
|
1.0
|
C37
|
D:7SR301
|
4.3
|
106.0
|
1.0
|
C
|
E:ARG78
|
4.3
|
95.2
|
1.0
|
CG
|
D:PHE105
|
4.3
|
99.5
|
1.0
|
CA
|
E:LEU79
|
4.3
|
89.1
|
1.0
|
CA
|
D:PHE105
|
4.4
|
91.4
|
1.0
|
CD1
|
D:PHE105
|
4.5
|
102.1
|
1.0
|
C
|
E:ILE75
|
4.5
|
89.2
|
1.0
|
CB
|
E:LEU79
|
4.6
|
90.1
|
1.0
|
C36
|
D:7SR301
|
4.7
|
106.1
|
1.0
|
CA
|
E:ILE75
|
4.7
|
90.4
|
1.0
|
CA
|
E:ARG78
|
4.7
|
95.4
|
1.0
|
CB
|
E:ILE75
|
4.7
|
88.6
|
1.0
|
N
|
D:PHE105
|
4.7
|
87.8
|
1.0
|
O
|
E:ARG78
|
4.8
|
97.5
|
1.0
|
C
|
D:ALA101
|
4.9
|
87.3
|
1.0
|
|
Bromine binding site 5 out
of 14 in 7vp9
Go back to
Bromine Binding Sites List in 7vp9
Bromine binding site 5 out
of 14 in the Crystal Structure of Human Clpp in Complex with ZG111
Mono view
Stereo pair view
|
A full contact list of Bromine with other atoms in the Br binding
site number 5 of Crystal Structure of Human Clpp in Complex with ZG111 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Br302
b:137.4
occ:1.00
|
BR1
|
D:7SR302
|
0.0
|
137.4
|
1.0
|
C39
|
D:7SR302
|
1.9
|
133.1
|
1.0
|
C41
|
D:7SR302
|
2.8
|
130.5
|
1.0
|
C38
|
D:7SR302
|
2.9
|
128.9
|
1.0
|
CG1
|
D:ILE75
|
3.5
|
84.6
|
1.0
|
CB
|
C:PHE105
|
3.5
|
99.6
|
1.0
|
CG
|
D:ARG78
|
3.8
|
103.3
|
1.0
|
CD1
|
D:ILE75
|
3.8
|
80.9
|
1.0
|
O
|
D:ILE75
|
3.9
|
96.0
|
1.0
|
CD1
|
C:PHE105
|
4.0
|
103.2
|
1.0
|
CG
|
C:PHE105
|
4.1
|
102.0
|
1.0
|
N
|
D:LEU79
|
4.1
|
99.6
|
1.0
|
O
|
C:ALA101
|
4.1
|
86.0
|
1.0
|
C42
|
D:7SR302
|
4.1
|
127.1
|
1.0
|
CB
|
D:ARG78
|
4.1
|
100.4
|
1.0
|
CA
|
C:PHE105
|
4.1
|
100.6
|
1.0
|
C37
|
D:7SR302
|
4.2
|
125.0
|
1.0
|
CA
|
D:LEU79
|
4.3
|
98.0
|
1.0
|
C
|
D:ARG78
|
4.4
|
101.2
|
1.0
|
N
|
C:PHE105
|
4.5
|
98.1
|
1.0
|
C36
|
D:7SR302
|
4.6
|
121.6
|
1.0
|
CB
|
D:LEU79
|
4.7
|
96.2
|
1.0
|
O
|
D:ARG78
|
4.8
|
100.4
|
1.0
|
CB
|
D:ILE75
|
4.8
|
91.2
|
1.0
|
C
|
D:ILE75
|
4.8
|
96.6
|
1.0
|
CA
|
D:ILE75
|
4.9
|
97.8
|
1.0
|
CA
|
D:ARG78
|
4.9
|
100.2
|
1.0
|
NH1
|
D:ARG78
|
5.0
|
122.3
|
1.0
|
|
Bromine binding site 6 out
of 14 in 7vp9
Go back to
Bromine Binding Sites List in 7vp9
Bromine binding site 6 out
of 14 in the Crystal Structure of Human Clpp in Complex with ZG111
Mono view
Stereo pair view
|
A full contact list of Bromine with other atoms in the Br binding
site number 6 of Crystal Structure of Human Clpp in Complex with ZG111 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Br301
b:120.5
occ:1.00
|
BR1
|
E:7SR301
|
0.0
|
120.5
|
1.0
|
C39
|
E:7SR301
|
2.0
|
115.8
|
1.0
|
C38
|
E:7SR301
|
2.9
|
115.6
|
1.0
|
C41
|
E:7SR301
|
2.9
|
113.6
|
1.0
|
CD1
|
F:ILE75
|
3.3
|
76.6
|
1.0
|
CB
|
E:PHE105
|
3.6
|
83.9
|
1.0
|
N
|
F:LEU79
|
3.8
|
88.6
|
1.0
|
O
|
F:ILE75
|
3.9
|
72.5
|
1.0
|
CA
|
F:LEU79
|
3.9
|
88.2
|
1.0
|
CD1
|
E:PHE105
|
3.9
|
88.3
|
1.0
|
CB
|
F:LEU79
|
3.9
|
87.1
|
1.0
|
CG
|
E:PHE105
|
4.0
|
88.3
|
1.0
|
CG
|
F:ARG78
|
4.0
|
84.7
|
1.0
|
C37
|
E:7SR301
|
4.2
|
114.1
|
1.0
|
CD1
|
F:LEU79
|
4.2
|
89.4
|
1.0
|
C42
|
E:7SR301
|
4.2
|
111.5
|
1.0
|
O
|
E:ALA101
|
4.2
|
80.6
|
1.0
|
C
|
F:ARG78
|
4.2
|
86.0
|
1.0
|
CA
|
E:PHE105
|
4.3
|
82.8
|
1.0
|
CB
|
F:ARG78
|
4.3
|
83.9
|
1.0
|
CG1
|
F:ILE75
|
4.3
|
78.4
|
1.0
|
CG
|
F:LEU79
|
4.6
|
88.9
|
1.0
|
NH1
|
F:ARG78
|
4.6
|
103.8
|
1.0
|
O
|
F:ARG78
|
4.7
|
90.1
|
1.0
|
C36
|
E:7SR301
|
4.7
|
110.7
|
1.0
|
N
|
E:PHE105
|
4.7
|
82.0
|
1.0
|
C
|
F:ILE75
|
4.9
|
78.2
|
1.0
|
CA
|
F:ARG78
|
4.9
|
83.7
|
1.0
|
CE1
|
E:PHE105
|
5.0
|
89.8
|
1.0
|
|
Bromine binding site 7 out
of 14 in 7vp9
Go back to
Bromine Binding Sites List in 7vp9
Bromine binding site 7 out
of 14 in the Crystal Structure of Human Clpp in Complex with ZG111
Mono view
Stereo pair view
|
A full contact list of Bromine with other atoms in the Br binding
site number 7 of Crystal Structure of Human Clpp in Complex with ZG111 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Br301
b:116.5
occ:1.00
|
BR1
|
G:7SR301
|
0.0
|
116.5
|
1.0
|
C39
|
G:7SR301
|
2.0
|
106.4
|
1.0
|
C38
|
G:7SR301
|
2.9
|
102.9
|
1.0
|
C41
|
G:7SR301
|
2.9
|
101.5
|
1.0
|
O
|
G:ILE75
|
3.6
|
74.3
|
1.0
|
CG1
|
G:ILE75
|
3.6
|
77.0
|
1.0
|
CB
|
F:PHE105
|
3.7
|
84.3
|
1.0
|
CG
|
G:LEU79
|
3.7
|
76.4
|
1.0
|
CG
|
G:ARG78
|
3.8
|
81.4
|
1.0
|
N
|
G:LEU79
|
3.9
|
75.9
|
1.0
|
O
|
F:ALA101
|
4.0
|
66.2
|
1.0
|
CB
|
G:ARG78
|
4.2
|
82.5
|
1.0
|
CA
|
G:LEU79
|
4.2
|
74.3
|
1.0
|
C37
|
G:7SR301
|
4.2
|
99.2
|
1.0
|
C42
|
G:7SR301
|
4.2
|
98.2
|
1.0
|
CD2
|
G:LEU79
|
4.3
|
78.6
|
1.0
|
C
|
G:ARG78
|
4.3
|
78.7
|
1.0
|
CD1
|
G:ILE75
|
4.3
|
78.1
|
1.0
|
CB
|
G:LEU79
|
4.4
|
74.8
|
1.0
|
CG
|
F:PHE105
|
4.4
|
90.7
|
1.0
|
CA
|
F:PHE105
|
4.5
|
80.3
|
1.0
|
C
|
G:ILE75
|
4.6
|
74.5
|
1.0
|
CD1
|
G:LEU79
|
4.7
|
76.0
|
1.0
|
CD1
|
F:PHE105
|
4.7
|
90.5
|
1.0
|
C36
|
G:7SR301
|
4.7
|
95.8
|
1.0
|
O
|
G:ARG78
|
4.7
|
77.3
|
1.0
|
N
|
F:PHE105
|
4.8
|
77.0
|
1.0
|
CA
|
G:ILE75
|
4.8
|
76.5
|
1.0
|
C
|
F:ALA101
|
4.8
|
65.7
|
1.0
|
CA
|
G:ARG78
|
4.9
|
80.9
|
1.0
|
CB
|
G:ILE75
|
4.9
|
76.5
|
1.0
|
|
Bromine binding site 8 out
of 14 in 7vp9
Go back to
Bromine Binding Sites List in 7vp9
Bromine binding site 8 out
of 14 in the Crystal Structure of Human Clpp in Complex with ZG111
Mono view
Stereo pair view
|
A full contact list of Bromine with other atoms in the Br binding
site number 8 of Crystal Structure of Human Clpp in Complex with ZG111 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
H:Br301
b:64.6
occ:1.00
|
BR1
|
H:7SR301
|
0.0
|
64.6
|
1.0
|
C39
|
H:7SR301
|
2.0
|
64.4
|
1.0
|
C41
|
H:7SR301
|
2.9
|
64.1
|
1.0
|
C38
|
H:7SR301
|
2.9
|
59.9
|
1.0
|
CG
|
H:ARG78
|
3.6
|
39.8
|
1.0
|
O
|
H:ILE75
|
3.6
|
40.6
|
1.0
|
CG1
|
H:ILE75
|
3.7
|
36.7
|
1.0
|
CG
|
H:LEU79
|
3.8
|
51.4
|
1.0
|
N
|
H:LEU79
|
3.8
|
45.6
|
1.0
|
CB
|
N:PHE105
|
3.9
|
49.4
|
1.0
|
CB
|
H:ARG78
|
3.9
|
41.7
|
1.0
|
CA
|
H:LEU79
|
4.1
|
45.8
|
1.0
|
C
|
H:ARG78
|
4.1
|
45.9
|
1.0
|
C42
|
H:7SR301
|
4.2
|
58.4
|
1.0
|
C37
|
H:7SR301
|
4.2
|
55.8
|
1.0
|
CD1
|
N:PHE105
|
4.3
|
46.8
|
1.0
|
CD1
|
H:ILE75
|
4.4
|
39.5
|
1.0
|
CB
|
H:LEU79
|
4.4
|
47.8
|
1.0
|
O
|
N:ALA101
|
4.4
|
50.9
|
1.0
|
CG
|
N:PHE105
|
4.4
|
46.1
|
1.0
|
CD2
|
H:LEU79
|
4.4
|
50.7
|
1.0
|
CA
|
N:PHE105
|
4.5
|
48.3
|
1.0
|
C
|
H:ILE75
|
4.6
|
40.3
|
1.0
|
O
|
H:ARG78
|
4.6
|
46.9
|
1.0
|
CD1
|
H:LEU79
|
4.6
|
54.2
|
1.0
|
CA
|
H:ARG78
|
4.7
|
44.0
|
1.0
|
C36
|
H:7SR301
|
4.7
|
52.9
|
1.0
|
CA
|
H:ILE75
|
4.8
|
42.4
|
1.0
|
CB
|
H:ILE75
|
4.9
|
38.6
|
1.0
|
N
|
N:PHE105
|
4.9
|
49.0
|
1.0
|
CD
|
H:ARG78
|
5.0
|
45.1
|
1.0
|
|
Bromine binding site 9 out
of 14 in 7vp9
Go back to
Bromine Binding Sites List in 7vp9
Bromine binding site 9 out
of 14 in the Crystal Structure of Human Clpp in Complex with ZG111
Mono view
Stereo pair view
|
A full contact list of Bromine with other atoms in the Br binding
site number 9 of Crystal Structure of Human Clpp in Complex with ZG111 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:Br301
b:59.0
occ:1.00
|
BR1
|
I:7SR301
|
0.0
|
59.0
|
1.0
|
C39
|
I:7SR301
|
1.9
|
42.4
|
1.0
|
C41
|
I:7SR301
|
2.9
|
38.2
|
1.0
|
C38
|
I:7SR301
|
2.9
|
35.1
|
1.0
|
CG
|
J:ARG78
|
3.5
|
38.3
|
1.0
|
CG1
|
J:ILE75
|
3.6
|
34.4
|
1.0
|
O
|
J:ILE75
|
3.7
|
37.7
|
1.0
|
CB
|
I:PHE105
|
3.8
|
32.1
|
1.0
|
N
|
J:LEU79
|
3.9
|
39.3
|
1.0
|
CB
|
J:ARG78
|
3.9
|
41.5
|
1.0
|
CG
|
J:LEU79
|
4.0
|
45.9
|
1.0
|
C37
|
I:7SR301
|
4.2
|
33.0
|
1.0
|
C
|
J:ARG78
|
4.2
|
41.5
|
1.0
|
C42
|
I:7SR301
|
4.2
|
37.5
|
1.0
|
CD1
|
I:PHE105
|
4.2
|
31.7
|
1.0
|
CA
|
J:LEU79
|
4.2
|
41.2
|
1.0
|
CD1
|
J:ILE75
|
4.3
|
34.4
|
1.0
|
CG
|
I:PHE105
|
4.3
|
33.4
|
1.0
|
CA
|
I:PHE105
|
4.4
|
32.6
|
1.0
|
O
|
I:ALA101
|
4.4
|
30.7
|
1.0
|
CB
|
J:LEU79
|
4.5
|
41.0
|
1.0
|
CD2
|
J:LEU79
|
4.6
|
45.8
|
1.0
|
O
|
J:ARG78
|
4.6
|
42.5
|
1.0
|
C
|
J:ILE75
|
4.6
|
38.9
|
1.0
|
C36
|
I:7SR301
|
4.6
|
36.8
|
1.0
|
CA
|
J:ARG78
|
4.7
|
43.3
|
1.0
|
CA
|
J:ILE75
|
4.8
|
41.9
|
1.0
|
N
|
I:PHE105
|
4.8
|
36.4
|
1.0
|
CB
|
J:ILE75
|
4.8
|
35.9
|
1.0
|
CD
|
J:ARG78
|
4.9
|
38.8
|
1.0
|
|
Bromine binding site 10 out
of 14 in 7vp9
Go back to
Bromine Binding Sites List in 7vp9
Bromine binding site 10 out
of 14 in the Crystal Structure of Human Clpp in Complex with ZG111
Mono view
Stereo pair view
|
A full contact list of Bromine with other atoms in the Br binding
site number 10 of Crystal Structure of Human Clpp in Complex with ZG111 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:Br302
b:53.8
occ:1.00
|
BR1
|
I:7SR302
|
0.0
|
53.8
|
1.0
|
C39
|
I:7SR302
|
1.9
|
46.0
|
1.0
|
C41
|
I:7SR302
|
2.8
|
40.7
|
1.0
|
C38
|
I:7SR302
|
2.8
|
41.9
|
1.0
|
CG
|
I:ARG78
|
3.6
|
36.1
|
1.0
|
CG1
|
I:ILE75
|
3.6
|
41.2
|
1.0
|
O
|
I:ILE75
|
3.7
|
32.7
|
1.0
|
CB
|
H:PHE105
|
3.7
|
37.8
|
1.0
|
N
|
I:LEU79
|
3.9
|
35.1
|
1.0
|
CD1
|
I:LEU79
|
3.9
|
40.0
|
1.0
|
CB
|
I:ARG78
|
4.0
|
36.6
|
1.0
|
C37
|
I:7SR302
|
4.1
|
38.7
|
1.0
|
C42
|
I:7SR302
|
4.1
|
40.4
|
1.0
|
O
|
H:ALA101
|
4.2
|
34.9
|
1.0
|
CA
|
I:LEU79
|
4.2
|
37.0
|
1.0
|
C
|
I:ARG78
|
4.2
|
37.5
|
1.0
|
CD1
|
H:PHE105
|
4.2
|
42.0
|
1.0
|
CD1
|
I:ILE75
|
4.3
|
45.2
|
1.0
|
CG
|
H:PHE105
|
4.3
|
39.3
|
1.0
|
CA
|
H:PHE105
|
4.4
|
41.0
|
1.0
|
CB
|
I:LEU79
|
4.4
|
36.6
|
1.0
|
C36
|
I:7SR302
|
4.6
|
37.3
|
1.0
|
O
|
I:ARG78
|
4.6
|
37.8
|
1.0
|
C
|
I:ILE75
|
4.6
|
40.8
|
1.0
|
CA
|
I:ARG78
|
4.7
|
41.7
|
1.0
|
CG
|
I:LEU79
|
4.7
|
40.2
|
1.0
|
N
|
H:PHE105
|
4.7
|
40.0
|
1.0
|
CA
|
I:ILE75
|
4.8
|
38.2
|
1.0
|
CB
|
I:ILE75
|
4.9
|
40.1
|
1.0
|
C
|
H:ALA101
|
5.0
|
37.4
|
1.0
|
|
Reference:
P.Wang,
T.Zhang,
X.Wang,
H.Xiao,
H.Li,
L.L.Zhou,
T.Yang,
B.Wei,
Z.Zhu,
L.Zhou,
S.Yang,
X.Lu,
Y.Zhang,
Y.Huang,
J.Gan,
C.G.Yang.
Aberrant Human Clpp Activation Disturbs Mitochondrial Proteome Homeostasis to Suppress Pancreatic Ductal Adenocarcinoma. Cell Chem Biol V. 29 1396 2022.
ISSN: ESSN 2451-9456
PubMed: 35905743
DOI: 10.1016/J.CHEMBIOL.2022.07.002
Page generated: Thu Jul 11 04:39:47 2024
|