Bromine in PDB 8wea: Human L-Type Voltage-Gated Calcium Channel CAV1.2 (Class II) in the Presence of Pinaverium at 3.2 Angstrom Resolution

The structure of Human L-Type Voltage-Gated Calcium Channel CAV1.2 (Class II) in the Presence of Pinaverium at 3.2 Angstrom Resolution also contains other interesting chemical elements:

Calcium

(Ca)

2 atoms

The binding sites of Bromine atom in the Human L-Type Voltage-Gated Calcium Channel CAV1.2 (Class II) in the Presence of Pinaverium at 3.2 Angstrom Resolution (pdb code 8wea). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Human L-Type Voltage-Gated Calcium Channel CAV1.2 (Class II) in the Presence of Pinaverium at 3.2 Angstrom Resolution, PDB code: 8wea:

Bromine binding site 1 out of 1 in the Human L-Type Voltage-Gated Calcium Channel CAV1.2 (Class II) in the Presence of Pinaverium at 3.2 Angstrom Resolution


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Human L-Type Voltage-Gated Calcium Channel CAV1.2 (Class II) in the Presence of Pinaverium at 3.2 Angstrom Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Br2303 b:20.0 occ:1.00 BR1 A:WB92303 0.0 20.0 1.0 C26 A:WB92303 1.9 20.0 1.0 C21 A:WB92303 2.9 20.0 1.0 C25 A:WB92303 2.9 20.0 1.0 C20 A:WB92303 3.1 20.0 1.0 C19 A:WB92303 3.5 20.0 1.0 C18 A:WB92303 3.5 20.0 1.0 N14 A:WB92303 3.7 20.0 1.0 C15 A:WB92303 4.0 20.0 1.0 C24 A:WB92303 4.2 20.0 1.0 C22 A:WB92303 4.2 20.0 1.0 C23 A:WB92303 4.7 20.0 1.0 O17 A:WB92303 4.8 20.0 1.0

S.Gao, X.Yao, J.Chen, G.Huang, X.Fan, L.Xue, Z.Li, T.Wu, Y.Zheng, J.Huang, X.Jin, Y.Wang, Z.Wang, Y.Yu, L.Liu, X.Pan, C.Song, N.Yan. Structural Basis For Human Ca V 1.2 Inhibition By Multiple Drugs and the Neurotoxin Calciseptine. Cell V. 186 5363 2023.
ISSN: ISSN 1097-4172
PubMed: 37972591
DOI: 10.1016/J.CELL.2023.10.007