Atomistry » Bromine » PDB 101d-1e5a » 1dis
Atomistry »
  Bromine »
    PDB 101d-1e5a »
      1dis »

Bromine in PDB 1dis: Dihydrofolate Reductase (E.C.1.5.1.3) Complex with Brodimoprim-4,6-Dicarboxylate

Enzymatic activity of Dihydrofolate Reductase (E.C.1.5.1.3) Complex with Brodimoprim-4,6-Dicarboxylate

All present enzymatic activity of Dihydrofolate Reductase (E.C.1.5.1.3) Complex with Brodimoprim-4,6-Dicarboxylate:
1.5.1.3;

Bromine Binding Sites:

The binding sites of Bromine atom in the Dihydrofolate Reductase (E.C.1.5.1.3) Complex with Brodimoprim-4,6-Dicarboxylate (pdb code 1dis). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Dihydrofolate Reductase (E.C.1.5.1.3) Complex with Brodimoprim-4,6-Dicarboxylate, PDB code: 1dis:

Bromine binding site 1 out of 1 in 1dis

Go back to Bromine Binding Sites List in 1dis
Bromine binding site 1 out of 1 in the Dihydrofolate Reductase (E.C.1.5.1.3) Complex with Brodimoprim-4,6-Dicarboxylate


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Dihydrofolate Reductase (E.C.1.5.1.3) Complex with Brodimoprim-4,6-Dicarboxylate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br163

b:0.0
occ:1.00
BR11 A:BDM163 0.0 0.0 1.0
C11 A:BDM163 1.9 0.0 1.0
HD3 A:PRO50 2.5 0.0 1.0
HD2 A:PRO50 2.6 0.0 1.0
C12 A:BDM163 2.9 0.0 1.0
C10 A:BDM163 2.9 0.0 1.0
O10 A:BDM163 3.0 0.0 1.0
CD A:PRO50 3.0 0.0 1.0
O12 A:BDM163 3.0 0.0 1.0
HA A:PHE49 3.2 0.0 1.0
HD1 A:PHE49 3.2 0.0 1.0
HD21 A:LEU27 3.3 0.0 1.0
HD22 A:LEU27 3.4 0.0 1.0
HG2 A:PRO50 3.5 0.0 1.0
H143 A:BDM163 3.6 0.0 1.0
CG A:PRO50 3.8 0.0 1.0
C14 A:BDM163 3.9 0.0 1.0
CD2 A:LEU27 3.9 0.0 1.0
H161 A:BDM163 4.0 0.0 1.0
HG3 A:PRO50 4.2 0.0 1.0
C13 A:BDM163 4.2 0.0 1.0
C9 A:BDM163 4.2 0.0 1.0
H162 A:BDM163 4.2 0.0 1.0
C15 A:BDM163 4.3 0.0 1.0
CD1 A:PHE49 4.3 0.0 1.0
N A:PRO50 4.3 0.0 1.0
CA A:PHE49 4.3 0.0 1.0
H142 A:BDM163 4.4 0.0 1.0
C16 A:BDM163 4.5 0.0 1.0
HD23 A:LEU27 4.5 0.0 1.0
O A:SER48 4.5 0.0 1.0
C8 A:BDM163 4.7 0.0 1.0
HB3 A:PHE49 4.7 0.0 1.0
HD13 A:LEU19 4.7 0.0 1.0
H151 A:BDM163 4.8 0.0 1.0
H141 A:BDM163 4.8 0.0 1.0
C A:PHE49 4.8 0.0 1.0
HG A:LEU27 4.8 0.0 1.0
HD12 A:LEU19 4.9 0.0 1.0
CB A:PHE49 4.9 0.0 1.0
HE1 A:PHE49 4.9 0.0 1.0

Reference:

W.D.Morgan, B.Birdsall, V.I.Polshakov, D.Sali, I.Kompis, J.Feeney. Solution Structure of A Brodimoprim Analogue in Its Complex with Lactobacillus Casei Dihydrofolate Reductase. Biochemistry V. 34 11690 1995.
ISSN: ISSN 0006-2960
PubMed: 7547901
DOI: 10.1021/BI00037A006
Page generated: Wed Jul 10 16:25:01 2024

Last articles

Cl in 4NHT
Cl in 4NO7
Cl in 4NML
Cl in 4NN3
Cl in 4NMW
Cl in 4NM7
Cl in 4NM5
Cl in 4NM3
Cl in 4NM0
Cl in 4NHQ
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy