Bromine in PDB 1gqp: APC10/DOC1 Subunit of S. Cerevisiae

The structure of APC10/DOC1 Subunit of S. Cerevisiae, PDB code: 1gqp was solved by S.W.N.Au, X.Leng, J.W.A.D.E.Harper, D.Barford, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.24 / 2.20
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	91.065, 91.065, 114.171, 90.00, 90.00, 120.00
R / Rfree (%)	21.3 / 24.4

The binding sites of Bromine atom in the APC10/DOC1 Subunit of S. Cerevisiae (pdb code 1gqp). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 6 binding sites of Bromine where determined in the APC10/DOC1 Subunit of S. Cerevisiae, PDB code: 1gqp:
Jump to Bromine binding site number: 1; 2; 3; 4; 5; 6;

Bromine binding site 1 out of 6 in the APC10/DOC1 Subunit of S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of APC10/DOC1 Subunit of S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ A:Br301 b:34.5 occ:1.00 O A:HOH477 3.2 31.8 1.0 NZ A:LYS243 3.5 32.3 1.0 CA A:GLY151 3.9 23.3 1.0 N A:GLN152 4.0 24.5 1.0 CG A:LYS243 4.2 21.6 1.0 CG A:GLN152 4.4 23.8 1.0 C A:GLY151 4.5 25.5 1.0 CE A:LYS243 4.6 28.6 1.0 CD A:LYS243 4.7 23.7 1.0 CD A:GLN152 4.8 22.3 1.0 CB A:GLN152 4.9 23.2 1.0 O A:GLY150 4.9 19.2 1.0 OE1 A:GLN152 5.0 23.3 1.0 O A:HOH431 5.0 29.9 1.0

Bromine binding site 2 out of 6 in the APC10/DOC1 Subunit of S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of APC10/DOC1 Subunit of S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ A:Br302 b:25.0 occ:1.00 N A:GLY131 3.4 26.7 1.0 CE1 A:PHE128 3.9 29.4 1.0 CD A:PRO133 4.0 26.1 1.0 CB A:PRO133 4.0 23.8 1.0 CG A:PRO133 4.1 23.6 1.0 CA A:GLY131 4.2 27.4 1.0 CD2 A:LEU130 4.2 25.7 1.0 CA A:LEU130 4.4 27.3 1.0 C A:LEU130 4.4 25.4 1.0 CD1 A:PHE128 4.6 26.9 1.0 N A:PRO133 4.7 24.2 1.0 C A:GLY131 4.7 27.3 1.0 N A:ASN132 4.7 25.5 1.0 CZ A:PHE128 4.8 25.9 1.0 CA A:PRO133 4.9 22.5 1.0

Bromine binding site 3 out of 6 in the APC10/DOC1 Subunit of S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 3 of APC10/DOC1 Subunit of S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ A:Br303 b:58.5 occ:1.00 CA A:HIS192 3.5 42.2 1.0 N A:GLN229 3.6 38.5 1.0 CD A:ARG163 3.7 59.3 1.0 O A:GLY191 3.7 38.3 1.0 CA A:CYS228 3.8 40.3 1.0 CB A:HIS192 3.8 43.0 1.0 N A:HIS192 3.8 40.6 1.0 C A:GLY191 3.9 38.6 1.0 C A:CYS228 4.0 39.3 1.0 CG A:ARG163 4.1 57.2 1.0 CB A:GLN229 4.2 39.0 1.0 NE A:ARG163 4.2 61.4 1.0 O A:LYS227 4.4 47.5 1.0 CA A:GLN229 4.5 38.3 1.0 CB A:ARG163 4.5 54.2 1.0 N A:CYS228 4.7 44.3 1.0 CB A:CYS228 4.7 41.0 1.0 CA A:GLY191 4.9 37.8 1.0 C A:HIS192 4.9 42.8 1.0 C A:LYS227 4.9 47.5 1.0 O A:CYS228 5.0 37.6 1.0

Bromine binding site 4 out of 6 in the APC10/DOC1 Subunit of S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 4 of APC10/DOC1 Subunit of S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ B:Br301 b:28.7 occ:1.00 CG B:PRO133 3.3 27.2 1.0 N B:GLY131 3.3 24.3 1.0 CE1 B:PHE128 3.8 28.6 1.0 CA B:GLY131 4.1 24.9 1.0 CD B:PRO133 4.1 26.2 1.0 CB B:PRO133 4.2 25.0 1.0 CD1 B:LEU130 4.2 27.6 1.0 C B:LEU130 4.3 24.7 1.0 CA B:LEU130 4.3 25.6 1.0 CD1 B:PHE128 4.5 27.6 1.0 N B:ASN132 4.6 24.9 1.0 N B:PRO133 4.6 24.9 1.0 C B:GLY131 4.6 26.2 1.0 CZ B:PHE128 4.8 26.6 1.0 CA B:PRO133 4.8 23.8 1.0 CG B:LEU130 4.9 27.9 1.0 O B:LYS129 5.0 24.2 1.0

Bromine binding site 5 out of 6 in the APC10/DOC1 Subunit of S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 5 of APC10/DOC1 Subunit of S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ B:Br302 b:44.7 occ:1.00 O B:HOH463 3.2 40.8 1.0 ND2 B:ASN82 3.2 34.3 1.0 OE1 B:GLN89 3.5 55.8 1.0 O B:HOH403 3.6 33.2 1.0 NE2 B:GLN89 3.6 56.5 1.0 CB B:GLN104 3.8 24.7 1.0 O A:HOH480 3.8 25.7 1.0 CD B:GLN89 4.0 57.0 1.0 CG B:GLN104 4.1 27.9 1.0 CG B:ASN82 4.2 36.5 1.0 CB B:ASN82 4.3 36.5 1.0 CG B:MET101 4.4 31.3 1.0 CA B:MET101 4.4 30.9 1.0 CA B:ASN82 4.5 39.0 1.0 CD2 B:HIS100 4.7 35.6 1.0 CB B:MET101 4.8 31.7 1.0 N B:GLY83 4.8 40.9 1.0 NE2 B:GLN104 4.8 23.0 1.0 NE2 B:HIS100 5.0 36.5 1.0 CD B:GLN104 5.0 26.5 1.0

Bromine binding site 6 out of 6 in the APC10/DOC1 Subunit of S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 6 of APC10/DOC1 Subunit of S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ B:Br303 b:55.0 occ:1.00 N B:GLN229 3.7 38.5 1.0 CA B:HIS192 3.7 44.4 1.0 CG B:ARG163 3.8 52.1 1.0 CA B:CYS228 3.8 42.4 1.0 CB B:HIS192 3.9 49.1 1.0 N B:HIS192 3.9 42.3 1.0 O B:GLY191 3.9 39.6 1.0 C B:GLY191 4.0 39.6 1.0 C B:CYS228 4.0 40.6 1.0 NE B:ARG163 4.0 57.6 1.0 CD B:ARG163 4.2 54.5 1.0 CB B:GLN229 4.2 39.1 1.0 ND1 B:HIS192 4.3 55.7 1.0 CB B:ARG163 4.5 49.4 1.0 O B:LYS227 4.6 47.8 1.0 CA B:GLN229 4.6 36.8 1.0 CG B:HIS192 4.6 53.6 1.0 N B:CYS228 4.7 44.6 1.0 CB B:CYS228 4.8 42.9 1.0 CA B:GLY191 4.9 38.6 1.0 O B:CYS228 4.9 41.4 1.0 C B:LYS227 5.0 47.5 1.0

S.W.N.Au, X.Leng, J.W.A.D.E.Harper, D.Barford. Implications For the Ubiquitination Reaction of the Anaphase-Promoting Complex From the Crystal Structure of the DOC1/APC10 Subunit. J.Mol.Biol. V. 316 955 2002.
ISSN: ISSN 0022-2836
PubMed: 11884135
DOI: 10.1006/JMBI.2002.5399