Bromine in PDB 1m5c: X-Ray Structure of the GLUR2 Ligand Binding Core (S1S2J) in Complex with Br-Hibo at 1.65 A Resolution

The structure of X-Ray Structure of the GLUR2 Ligand Binding Core (S1S2J) in Complex with Br-Hibo at 1.65 A Resolution, PDB code: 1m5c was solved by A.Hogner, J.S.Kastrup, R.Jin, T.Liljefors, M.L.Mayer, J.Egebjerg, I.K.Larsen, E.Gouaux, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.50 / 1.65
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	87.878, 64.009, 48.032, 90.00, 90.00, 90.00
R / Rfree (%)	19.2 / 22.1

The binding sites of Bromine atom in the X-Ray Structure of the GLUR2 Ligand Binding Core (S1S2J) in Complex with Br-Hibo at 1.65 A Resolution (pdb code 1m5c). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the X-Ray Structure of the GLUR2 Ligand Binding Core (S1S2J) in Complex with Br-Hibo at 1.65 A Resolution, PDB code: 1m5c:

Bromine binding site 1 out of 1 in the X-Ray Structure of the GLUR2 Ligand Binding Core (S1S2J) in Complex with Br-Hibo at 1.65 A Resolution


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of X-Ray Structure of the GLUR2 Ligand Binding Core (S1S2J) in Complex with Br-Hibo at 1.65 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Br611 b:19.3 occ:1.00 BR1 A:BRH611 0.0 19.3 1.0 C5 A:BRH611 1.8 14.8 1.0 C4 A:BRH611 2.9 15.3 1.0 C6 A:BRH611 3.0 19.7 1.0 OE2 A:GLU13 3.3 16.9 1.0 O3 A:BRH611 3.4 20.6 1.0 O A:HOH751 3.5 25.6 1.0 OG1 A:THR174 3.6 16.7 1.0 C3 A:BRH611 3.6 14.2 1.0 OH A:TYR61 3.6 16.4 1.0 O A:HOH637 3.7 18.6 1.0 CD A:GLU13 3.8 16.7 1.0 CE A:MET196 3.8 18.5 1.0 CE2 A:TYR61 3.8 12.5 1.0 CD2 A:LEU138 3.9 17.1 1.0 CZ A:TYR61 3.9 13.7 1.0 OE1 A:GLU13 4.0 19.4 1.0 O4 A:BRH611 4.1 17.1 1.0 N2 A:BRH611 4.1 17.8 1.0 O A:HOH672 4.3 19.2 1.0 CG A:GLU13 4.7 17.3 1.0 OE1 A:GLU193 4.7 14.2 1.0 CD2 A:TYR61 4.8 13.6 1.0 SD A:MET196 4.8 17.2 1.0 C2 A:BRH611 4.8 12.3 1.0 CG A:MET196 4.9 17.9 1.0 CE1 A:TYR61 4.9 12.4 1.0 N1 A:BRH611 4.9 11.7 1.0 CB A:THR174 5.0 17.3 1.0

A.Hogner, J.S.Kastrup, R.Jin, T.Liljefors, M.L.Mayer, J.Egebjerg, I.K.Larsen, E.Gouaux. Structural Basis For Ampa Receptor Activation and Ligand Selectivity: Crystal Structures of Five Agonist Complexes with the GLUR2 Ligand-Binding Core J.Mol.Biol. V. 322 93 2002.
ISSN: ISSN 0022-2836
PubMed: 12215417
DOI: 10.1016/S0022-2836(02)00650-2