Bromine in PDB 1m5d: X-Ray Structure of the GLUR2 Ligand Binding Core (S1S2J-Y702F) in Complex with Br-Hibo at 1.73 A Resolution

The structure of X-Ray Structure of the GLUR2 Ligand Binding Core (S1S2J-Y702F) in Complex with Br-Hibo at 1.73 A Resolution, PDB code: 1m5d was solved by A.Hogner, J.S.Kastrup, R.Jin, T.Liljefors, M.L.Mayer, J.Egebjerg, I.K.Larsen, E.Gouaux, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.59 / 1.73
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	87.139, 63.681, 47.914, 90.00, 90.00, 90.00
R / Rfree (%)	18.6 / 21.5

The binding sites of Bromine atom in the X-Ray Structure of the GLUR2 Ligand Binding Core (S1S2J-Y702F) in Complex with Br-Hibo at 1.73 A Resolution (pdb code 1m5d). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the X-Ray Structure of the GLUR2 Ligand Binding Core (S1S2J-Y702F) in Complex with Br-Hibo at 1.73 A Resolution, PDB code: 1m5d:

Bromine binding site 1 out of 1 in the X-Ray Structure of the GLUR2 Ligand Binding Core (S1S2J-Y702F) in Complex with Br-Hibo at 1.73 A Resolution


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of X-Ray Structure of the GLUR2 Ligand Binding Core (S1S2J-Y702F) in Complex with Br-Hibo at 1.73 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Br611 b:44.2 occ:1.00 BR1 A:BRH611 0.0 44.2 1.0 C5 A:BRH611 1.8 36.7 1.0 C4 A:BRH611 2.8 31.9 1.0 C6 A:BRH611 3.0 37.5 1.0 OH A:TYR61 3.3 26.1 1.0 OE2 A:GLU13 3.4 30.7 1.0 O3 A:BRH611 3.4 40.7 1.0 C3 A:BRH611 3.5 26.6 1.0 CE A:MET196 3.6 36.3 1.0 CZ A:TYR61 3.7 21.5 1.0 CD1 A:LEU138 3.7 24.4 1.0 OG1 A:THR174 3.8 25.6 1.0 CE2 A:TYR61 3.8 20.9 1.0 CD A:GLU13 3.9 28.2 1.0 O4 A:BRH611 4.0 34.2 1.0 N2 A:BRH611 4.1 35.8 1.0 OE1 A:GLU193 4.3 19.0 1.0 SD A:MET196 4.3 36.1 1.0 OE1 A:GLU13 4.4 30.8 1.0 N1 A:BRH611 4.4 18.1 1.0 CG A:GLU13 4.5 23.4 1.0 C2 A:BRH611 4.5 19.1 1.0 CE1 A:TYR61 4.6 20.4 1.0 CG A:MET196 4.7 28.7 1.0 O A:HOH668 4.8 35.3 1.0 CD2 A:TYR61 4.8 20.5 1.0 CG A:LEU138 5.0 24.1 1.0

A.Hogner, J.S.Kastrup, R.Jin, T.Liljefors, M.L.Mayer, J.Egebjerg, I.K.Larsen, E.Gouaux. Structural Basis For Ampa Receptor Activation and Ligand Selectivity: Crystal Structures of Five Agonist Complexes with the GLUR2 Ligand-Binding Core J.Mol.Biol. V. 322 93 2002.
ISSN: ISSN 0022-2836
PubMed: 12215417
DOI: 10.1016/S0022-2836(02)00650-2