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Atomistry » Bromine » PDB 1m9t-1p1y » 1oon » |
Bromine in PDB 1oon: Nitroreductase From E-Coli in Complex with the Dinitrobenzamide Prodrug SN27217Enzymatic activity of Nitroreductase From E-Coli in Complex with the Dinitrobenzamide Prodrug SN27217
All present enzymatic activity of Nitroreductase From E-Coli in Complex with the Dinitrobenzamide Prodrug SN27217:
1.6.99.7; Protein crystallography data
The structure of Nitroreductase From E-Coli in Complex with the Dinitrobenzamide Prodrug SN27217, PDB code: 1oon
was solved by
E.Johansson,
G.N.Parkinson,
W.A.Denny,
S.Neidle,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the Nitroreductase From E-Coli in Complex with the Dinitrobenzamide Prodrug SN27217
(pdb code 1oon). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Nitroreductase From E-Coli in Complex with the Dinitrobenzamide Prodrug SN27217, PDB code: 1oon: Jump to Bromine binding site number: 1; 2; Bromine binding site 1 out of 2 in 1oonGo back to![]() ![]()
Bromine binding site 1 out
of 2 in the Nitroreductase From E-Coli in Complex with the Dinitrobenzamide Prodrug SN27217
![]() Mono view ![]() Stereo pair view
Bromine binding site 2 out of 2 in 1oonGo back to![]() ![]()
Bromine binding site 2 out
of 2 in the Nitroreductase From E-Coli in Complex with the Dinitrobenzamide Prodrug SN27217
![]() Mono view ![]() Stereo pair view
Reference:
E.Johansson,
G.N.Parkinson,
W.A.Denny,
S.Neidle.
Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs and of the Enzyme Active Form J.Med.Chem. V. 46 4009 2003.
Page generated: Mon Jul 7 03:37:36 2025
ISSN: ISSN 0022-2623 PubMed: 12954054 DOI: 10.1021/JM030843B |
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