Bromine in PDB 1roc: Crystal Structure of the Histone Deposition Protein ASF1

The structure of Crystal Structure of the Histone Deposition Protein ASF1, PDB code: 1roc was solved by S.M.Daganzo, J.P.Erzberger, W.M.Lam, E.Skordalakes, R.Zhang, A.A.Franco, S.J.Brill, P.D.Adams, J.M.Berger, P.D.Kaufman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.50
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	94.395, 31.702, 53.625, 90.00, 124.55, 90.00
R / Rfree (%)	19.8 / 24.6

The binding sites of Bromine atom in the Crystal Structure of the Histone Deposition Protein ASF1 (pdb code 1roc). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 9 binding sites of Bromine where determined in the Crystal Structure of the Histone Deposition Protein ASF1, PDB code: 1roc:
Jump to Bromine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9;

Bromine binding site 1 out of 9 in the Crystal Structure of the Histone Deposition Protein ASF1


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of the Histone Deposition Protein ASF1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Br201 b:29.6 occ:1.00 O A:HOH220 3.3 21.1 1.0 NH1 A:ARG145 3.4 21.7 1.0 CD2 A:LEU96 3.7 14.1 1.0 CG A:ARG145 3.9 15.5 1.0 CB A:ARG145 4.0 13.6 1.0 CD A:ARG145 4.0 18.5 1.0 CA A:GLY110 4.1 12.5 1.0 O A:ARG145 4.4 12.1 1.0 N A:GLY110 4.5 12.9 1.0 CZ A:ARG145 4.5 20.3 1.0 CD A:ARG108 4.6 25.5 1.0 NE A:ARG145 4.7 19.8 1.0 O A:HOH355 4.7 32.3 1.0

Bromine binding site 2 out of 9 in the Crystal Structure of the Histone Deposition Protein ASF1


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Crystal Structure of the Histone Deposition Protein ASF1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Br202 b:30.7 occ:1.00 N A:TYR117 3.4 15.2 1.0 O A:HOH347 3.5 29.2 1.0 CG A:ARG123 3.8 16.1 1.0 CA A:GLU116 3.9 17.6 1.0 CA A:ARG123 4.1 18.2 1.0 CD2 A:TYR117 4.1 19.4 1.0 C A:GLU116 4.1 16.8 1.0 CB A:TYR117 4.1 14.6 1.0 CB A:ARG123 4.2 17.6 1.0 CG A:GLU116 4.3 22.8 1.0 CA A:TYR117 4.4 14.9 1.0 CB A:GLU116 4.4 18.9 1.0 O A:ASN115 4.4 18.6 1.0 CB A:LEU89 4.4 23.9 1.0 O A:LEU89 4.5 24.0 1.0 CG A:TYR117 4.5 16.1 1.0 CD A:ARG123 4.6 16.6 1.0 CD1 A:LEU89 4.6 28.8 1.0 O A:ARG123 4.7 19.8 1.0 CG A:LEU89 4.8 26.0 1.0 C A:ARG123 4.9 19.2 1.0 O A:HOH287 5.0 22.6 1.0 N A:GLU116 5.0 17.5 1.0 C A:LEU89 5.0 23.4 1.0

Bromine binding site 3 out of 9 in the Crystal Structure of the Histone Deposition Protein ASF1


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 3 of Crystal Structure of the Histone Deposition Protein ASF1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Br203 b:39.9 occ:1.00 N A:GLU142 3.4 15.6 1.0 C A:LEU140 3.5 14.1 1.0 CA A:LEU140 3.6 14.5 1.0 CB A:GLU142 3.6 17.1 1.0 O A:HOH293 3.7 29.4 1.0 N A:ALA141 3.7 14.2 1.0 O A:HOH364 3.7 29.6 1.0 CB A:LEU140 3.8 14.9 1.0 CG A:GLU142 3.9 20.8 1.0 CA A:GLU142 3.9 16.6 1.0 O A:LEU140 4.0 13.5 1.0 CG A:LEU140 4.3 18.5 1.0 N A:LYS143 4.4 16.0 1.0 C A:GLU142 4.4 16.3 1.0 CG A:LYS143 4.4 20.8 1.0 C A:ALA141 4.5 15.5 1.0 CA A:ALA141 4.6 14.8 1.0 CD A:GLU142 4.8 26.9 1.0 O A:ILE139 4.9 14.7 1.0 N A:LEU140 5.0 13.6 1.0

Bromine binding site 4 out of 9 in the Crystal Structure of the Histone Deposition Protein ASF1


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 4 of Crystal Structure of the Histone Deposition Protein ASF1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Br204 b:46.3 occ:1.00 O A:HOH344 2.5 27.9 1.0 N A:ILE151 3.3 18.0 1.0 NE1 A:TRP153 3.3 18.3 1.0 O A:ILE151 3.3 17.7 1.0 CA A:ASN150 3.7 18.0 1.0 CA A:SER2 3.7 19.9 1.0 CB A:SER2 3.7 19.4 1.0 OG A:SER2 3.8 19.8 1.0 C A:ASN150 4.0 18.4 1.0 BR A:BR206 4.1 55.0 1.0 O A:PHE149 4.2 14.7 1.0 C A:ILE151 4.2 18.2 1.0 CG1 A:ILE151 4.2 17.8 1.0 CD1 A:TRP153 4.2 18.7 1.0 N A:SER2 4.2 21.9 1.0 CA A:ILE151 4.2 17.8 1.0 OD1 A:ASN150 4.2 26.5 1.0 CE2 A:TRP153 4.3 16.2 1.0 CB A:ASN150 4.3 18.2 1.0 CZ2 A:TRP153 4.5 15.0 1.0 N A:ASN150 4.7 16.5 1.0 CG A:ASN150 4.8 21.4 1.0 CB A:ILE151 4.8 17.3 1.0 C A:PHE149 4.9 15.6 1.0 C A:ALA1 5.0 25.3 1.0 C A:SER2 5.0 18.7 1.0

Bromine binding site 5 out of 9 in the Crystal Structure of the Histone Deposition Protein ASF1


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 5 of Crystal Structure of the Histone Deposition Protein ASF1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Br205 b:57.4 occ:1.00 CG2 A:VAL69 4.3 14.6 1.0 CB A:VAL69 4.9 13.7 1.0 CG1 A:VAL69 4.9 15.9 1.0

Bromine binding site 6 out of 9 in the Crystal Structure of the Histone Deposition Protein ASF1


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 6 of Crystal Structure of the Histone Deposition Protein ASF1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Br206 b:55.0 occ:1.00 OD1 A:ASN150 3.0 26.5 1.0 O A:HOH238 3.4 26.7 1.0 O A:HOH344 3.8 27.9 1.0 O A:PHE149 3.8 14.7 1.0 CG A:ASN150 3.9 21.4 1.0 C A:PHE149 4.0 15.6 1.0 CB A:ARG148 4.0 14.6 1.0 N A:ASN150 4.1 16.5 1.0 O A:HOH299 4.1 30.3 1.0 BR A:BR204 4.1 46.3 1.0 CA A:ASN150 4.1 18.0 1.0 CB A:SER2 4.2 19.4 1.0 N A:PHE149 4.6 14.3 1.0 CB A:ASN150 4.6 18.2 1.0 OG A:SER2 4.7 19.8 1.0 C A:ARG148 4.7 14.0 1.0 ND2 A:ASN150 4.7 24.4 1.0 CA A:PHE149 4.8 14.9 1.0 O A:HOH241 4.8 25.3 1.0 CG A:ARG148 4.8 15.1 1.0 CD A:ARG148 4.9 16.1 1.0 CA A:ARG148 5.0 14.0 1.0

Bromine binding site 7 out of 9 in the Crystal Structure of the Histone Deposition Protein ASF1


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 7 of Crystal Structure of the Histone Deposition Protein ASF1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Br207 b:53.9 occ:1.00 O A:HOH330 3.2 24.4 1.0 CD A:LYS10 3.9 24.6 1.0 NZ A:LYS10 4.6 32.7 1.0 OE1 A:GLU25 4.6 26.7 1.0 O A:HOH296 4.8 30.7 1.0 CE A:LYS10 4.8 29.0 1.0

Bromine binding site 8 out of 9 in the Crystal Structure of the Histone Deposition Protein ASF1


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 8 of Crystal Structure of the Histone Deposition Protein ASF1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Br208 b:64.5 occ:1.00 CD A:ARG104 3.4 15.1 1.0 N A:VAL152 3.4 18.4 1.0 CA A:ILE151 3.8 17.8 1.0 CB A:ILE151 4.1 17.3 1.0 NE A:ARG104 4.1 15.9 1.0 C A:ILE151 4.1 18.2 1.0 CB A:VAL152 4.3 19.0 1.0 CG2 A:ILE151 4.4 17.1 1.0 CA A:VAL152 4.5 19.2 1.0 CG A:ARG104 4.5 16.1 1.0 O A:ASN150 4.5 19.5 1.0 CG2 A:VAL152 4.5 20.4 1.0 CB A:ARG104 4.7 14.5 1.0 O A:HOH328 4.8 31.3 1.0 O A:VAL152 4.9 18.4 1.0 N A:ILE151 5.0 18.0 1.0

Bromine binding site 9 out of 9 in the Crystal Structure of the Histone Deposition Protein ASF1


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 9 of Crystal Structure of the Histone Deposition Protein ASF1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Br209 b:0.9 occ:1.00 ND2 A:ASN13 3.9 27.0 1.0 O A:HOH323 3.9 29.8 1.0 CD1 A:LEU12 4.3 19.9 1.0 CD2 A:LEU12 4.4 20.8 1.0 OD1 A:ASN13 4.5 29.0 1.0 CB A:LEU12 4.5 15.3 1.0 CG A:ASN13 4.5 23.8 1.0 OE1 A:GLU23 4.6 30.0 1.0 CG A:LEU12 4.7 18.0 1.0

S.M.Daganzo, J.P.Erzberger, W.M.Lam, E.Skordalakes, R.Zhang, A.A.Franco, S.J.Brill, P.D.Adams, J.M.Berger, P.D.Kaufman. Structure and Function of the Conserved Core of Histone Deposition Protein ASF1. Curr.Biol. V. 13 2148 2003.
ISSN: ISSN 0960-9822
PubMed: 14680630
DOI: 10.1016/J.CUB.2003.11.027