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Atomistry » Bromine » PDB 1p2x-1to3 » 1rsi » |
Bromine in PDB 1rsi: Dhna Complex with 2-Amino-5-Bromo-3-Hydroxy-6-PhenylpyrimidineEnzymatic activity of Dhna Complex with 2-Amino-5-Bromo-3-Hydroxy-6-Phenylpyrimidine
All present enzymatic activity of Dhna Complex with 2-Amino-5-Bromo-3-Hydroxy-6-Phenylpyrimidine:
4.1.2.25; Protein crystallography data
The structure of Dhna Complex with 2-Amino-5-Bromo-3-Hydroxy-6-Phenylpyrimidine, PDB code: 1rsi
was solved by
W.J.Sanders,
V.L.Nienaber,
C.G.Lerner,
J.O.Mccall,
S.M.Merrick,
S.J.Swanson,
J.E.Harlan,
V.S.Stoll,
G.F.Stamper,
S.F.Betz,
K.R.Condroski,
R.P.Meadows,
J.M.Severin,
K.A.Walter,
P.Magdalinos,
C.G.Jakob,
R.Wagner,
B.A.Beutel,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the Dhna Complex with 2-Amino-5-Bromo-3-Hydroxy-6-Phenylpyrimidine
(pdb code 1rsi). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Dhna Complex with 2-Amino-5-Bromo-3-Hydroxy-6-Phenylpyrimidine, PDB code: 1rsi: Bromine binding site 1 out of 1 in 1rsiGo back to Bromine Binding Sites List in 1rsi
Bromine binding site 1 out
of 1 in the Dhna Complex with 2-Amino-5-Bromo-3-Hydroxy-6-Phenylpyrimidine
Mono view Stereo pair view
Reference:
W.J.Sanders,
V.L.Nienaber,
C.G.Lerner,
J.O.Mccall,
S.M.Merrick,
S.J.Swanson,
J.E.Harlan,
V.S.Stoll,
G.F.Stamper,
S.F.Betz,
K.R.Condroski,
R.P.Meadows,
J.M.Severin,
K.A.Walter,
P.Magdalinos,
C.G.Jakob,
R.Wagner,
B.A.Beutel.
Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using Crystalead High-Throughput X-Ray Crystallographic Screening and Structure-Directed Lead Optimization. J.Med.Chem. V. 47 1709 2004.
Page generated: Sat Dec 12 02:03:54 2020
ISSN: ISSN 0022-2623 PubMed: 15027862 DOI: 10.1021/JM030497Y |
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