Atomistry » Bromine » PDB 1z76-2cej » 2b63
Atomistry »
  Bromine »
    PDB 1z76-2cej »
      2b63 »

Bromine in PDB 2b63: Complete Rna Polymerase II-Rna Inhibitor Complex

Enzymatic activity of Complete Rna Polymerase II-Rna Inhibitor Complex

All present enzymatic activity of Complete Rna Polymerase II-Rna Inhibitor Complex:
2.7.7.6;

Protein crystallography data

The structure of Complete Rna Polymerase II-Rna Inhibitor Complex, PDB code: 2b63 was solved by H.Kettenberger, A.Eisenfuehr, F.Brueckner, M.Theis, M.Famulok, P.Cramer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 3.80
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 224.585, 399.815, 286.727, 90.00, 90.00, 90.00
R / Rfree (%) 25.2 / 27.3

Other elements in 2b63:

The structure of Complete Rna Polymerase II-Rna Inhibitor Complex also contains other interesting chemical elements:

Magnesium (Mg) 1 atom
Zinc (Zn) 8 atoms

Bromine Binding Sites:

The binding sites of Bromine atom in the Complete Rna Polymerase II-Rna Inhibitor Complex (pdb code 2b63). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 4 binding sites of Bromine where determined in the Complete Rna Polymerase II-Rna Inhibitor Complex, PDB code: 2b63:
Jump to Bromine binding site number: 1; 2; 3; 4;

Bromine binding site 1 out of 4 in 2b63

Go back to Bromine Binding Sites List in 2b63
Bromine binding site 1 out of 4 in the Complete Rna Polymerase II-Rna Inhibitor Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Complete Rna Polymerase II-Rna Inhibitor Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Br12

b:0.3
occ:1.00
BR R:5BU12 0.0 0.3 1.0
C5 R:5BU12 2.0 0.6 1.0
C4 R:5BU12 3.0 0.6 1.0
C6 R:5BU12 3.0 0.3 1.0
O4 R:5BU12 3.2 0.9 1.0
O2' R:A10 4.0 1.0 1.0
OP2 R:U11 4.1 0.7 1.0
C2' R:A10 4.2 0.1 1.0
N3 R:5BU12 4.2 0.9 1.0
N1 R:5BU12 4.3 0.2 1.0
C2 R:5BU12 4.8 0.6 1.0
OE2 B:GLU1120 4.9 99.4 1.0
C5' R:U11 4.9 0.0 1.0
O3' R:A10 5.0 0.2 1.0

Bromine binding site 2 out of 4 in 2b63

Go back to Bromine Binding Sites List in 2b63
Bromine binding site 2 out of 4 in the Complete Rna Polymerase II-Rna Inhibitor Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Complete Rna Polymerase II-Rna Inhibitor Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Br17

b:0.3
occ:1.00
BR R:5BU17 0.0 0.3 1.0
C5 R:5BU17 1.9 0.6 1.0
C6 R:5BU17 2.8 0.0 1.0
C4 R:5BU17 2.9 0.3 1.0
C4 R:G16 3.1 95.6 1.0
O4 R:5BU17 3.2 0.8 1.0
C5 R:G16 3.2 96.8 1.0
N9 R:G16 3.2 94.3 1.0
C8 R:G16 3.3 96.0 1.0
N7 R:G16 3.4 96.9 1.0
N3 R:G16 3.7 95.6 1.0
C3' R:G16 3.8 90.8 1.0
C2' R:G16 3.8 91.0 1.0
C6 R:G16 3.9 97.0 1.0
C1' R:G16 4.0 91.9 1.0
N1 R:5BU17 4.1 0.3 1.0
N3 R:5BU17 4.1 0.8 1.0
C2 R:G16 4.2 96.2 1.0
N1 R:G16 4.3 96.2 1.0
O5' R:5BU17 4.4 90.9 1.0
O5' R:G16 4.4 88.2 1.0
OP2 R:5BU17 4.6 88.8 1.0
O4' R:G16 4.7 91.2 1.0
O6 R:G16 4.7 98.0 1.0
C2 R:5BU17 4.7 0.9 1.0
C4' R:G16 4.7 90.5 1.0
O3' R:G16 4.8 90.5 1.0
O4' R:5BU17 4.9 0.8 1.0
P R:5BU17 4.9 90.2 1.0

Bromine binding site 3 out of 4 in 2b63

Go back to Bromine Binding Sites List in 2b63
Bromine binding site 3 out of 4 in the Complete Rna Polymerase II-Rna Inhibitor Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 3 of Complete Rna Polymerase II-Rna Inhibitor Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Br27

b:0.2
occ:1.00
BR R:5BU27 0.0 0.2 1.0
C5 R:5BU27 1.9 0.4 1.0
C6 R:5BU27 2.8 0.1 1.0
C4 R:5BU27 3.0 0.3 1.0
O4 R:5BU27 3.3 0.2 1.0
BR R:5BU28 3.3 0.2 1.0
C2 R:C26 3.8 0.4 1.0
N1 R:C26 3.8 0.3 1.0
N3 R:C26 3.8 0.7 1.0
C4 R:C26 3.8 0.7 1.0
C6 R:C26 3.8 0.7 1.0
C5 R:C26 3.8 0.6 1.0
C3' R:C26 3.8 0.9 1.0
C2' R:C26 4.0 0.8 1.0
O5' R:5BU27 4.0 0.9 1.0
N1 R:5BU27 4.1 0.3 1.0
N3 R:5BU27 4.2 0.4 1.0
C5 R:5BU28 4.2 0.4 1.0
O2 R:C26 4.4 0.8 1.0
O3' R:C26 4.4 0.9 1.0
N4 R:C26 4.5 0.0 1.0
O4 R:5BU28 4.5 0.4 1.0
C1' R:C26 4.5 0.5 1.0
C4 R:5BU28 4.6 1.0 1.0
C5' R:5BU27 4.6 0.8 1.0
C2 R:5BU27 4.8 0.2 1.0
O4' R:5BU27 4.9 0.2 1.0
P R:5BU27 5.0 0.1 1.0

Bromine binding site 4 out of 4 in 2b63

Go back to Bromine Binding Sites List in 2b63
Bromine binding site 4 out of 4 in the Complete Rna Polymerase II-Rna Inhibitor Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 4 of Complete Rna Polymerase II-Rna Inhibitor Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Br28

b:0.2
occ:1.00
BR R:5BU28 0.0 0.2 1.0
C5 R:5BU28 2.1 0.4 1.0
C4 R:5BU28 3.0 1.0 1.0
C6 R:5BU28 3.1 0.3 1.0
O4 R:5BU28 3.3 0.4 1.0
BR R:5BU27 3.3 0.2 1.0
C5 R:5BU27 3.6 0.4 1.0
C6 R:5BU27 4.0 0.1 1.0
C4 R:5BU27 4.3 0.3 1.0
N3 R:5BU28 4.3 0.9 1.0
N1 R:5BU28 4.4 0.4 1.0
C5' R:5BU27 4.4 0.8 1.0
O4 R:5BU27 4.6 0.2 1.0
N1 R:5BU27 4.8 0.3 1.0
O5' R:5BU27 4.8 0.9 1.0
C2 R:5BU28 4.9 0.8 1.0

Reference:

H.Kettenberger, A.Eisenfuehr, F.Brueckner, M.Theis, M.Famulok, P.Cramer. Structure of An Rna Polymerase II-Rna Inhibitor Complex Elucidates Transcription Regulation By Noncoding Rnas Nat.Struct.Mol.Biol. V. 13 44 2006.
ISSN: ISSN 1545-9993
PubMed: 16341226
DOI: 10.1038/NSMB1032
Page generated: Sat Dec 12 02:05:19 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy