Bromine in PDB 2e4i: Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines
Bromine Binding Sites:
The binding sites of Bromine atom in the Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines
(pdb code 2e4i). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total 5 binding sites of Bromine where determined in the
Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines, PDB code: 2e4i:
Jump to Bromine binding site number:
1;
2;
3;
4;
5;
Bromine binding site 1 out
of 5 in 2e4i
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Bromine Binding Sites List in 2e4i
Bromine binding site 1 out
of 5 in the Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines
Mono view
Stereo pair view
|
A full contact list of Bromine with other atoms in the Br binding
site number 1 of Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Br2
b:0.0
occ:1.00
|
BR
|
A:BGM2
|
0.0
|
0.0
|
1.0
|
C8
|
A:BGM2
|
1.9
|
0.0
|
1.0
|
H4'
|
A:DA7
|
2.8
|
0.0
|
1.0
|
N7
|
A:BGM2
|
2.8
|
0.0
|
1.0
|
H1'
|
A:BGM2
|
2.9
|
0.0
|
1.0
|
N9
|
A:BGM2
|
2.9
|
0.0
|
1.0
|
H5''
|
A:DA7
|
2.9
|
0.0
|
1.0
|
H5'
|
A:DA7
|
2.9
|
0.0
|
1.0
|
O4
|
A:DT5
|
2.9
|
0.0
|
1.0
|
C5'
|
A:DA7
|
3.2
|
0.0
|
1.0
|
H22
|
A:BGM8
|
3.2
|
0.0
|
1.0
|
C4'
|
A:DA7
|
3.3
|
0.0
|
1.0
|
C1'
|
A:BGM2
|
3.3
|
0.0
|
1.0
|
O4'
|
A:DA7
|
3.5
|
0.0
|
1.0
|
O4'
|
A:BGM2
|
3.7
|
0.0
|
1.0
|
C4
|
A:DT5
|
3.8
|
0.0
|
1.0
|
HO5'
|
A:DA1
|
3.9
|
0.0
|
1.0
|
C5
|
A:BGM2
|
4.0
|
0.0
|
1.0
|
N2
|
A:BGM8
|
4.0
|
0.0
|
1.0
|
C4
|
A:BGM2
|
4.0
|
0.0
|
1.0
|
H21
|
A:BGM8
|
4.1
|
0.0
|
1.0
|
H72
|
A:DT5
|
4.2
|
0.0
|
1.0
|
O5'
|
A:DA1
|
4.3
|
0.0
|
1.0
|
H73
|
A:DT5
|
4.3
|
0.0
|
1.0
|
H1'
|
A:DG3
|
4.3
|
0.0
|
1.0
|
H3
|
A:DT5
|
4.4
|
0.0
|
1.0
|
N3
|
A:DT5
|
4.5
|
0.0
|
1.0
|
C7
|
A:DT5
|
4.6
|
0.0
|
1.0
|
C5
|
A:DT5
|
4.6
|
0.0
|
1.0
|
O5'
|
A:DA7
|
4.6
|
0.0
|
1.0
|
N3
|
A:DG3
|
4.6
|
0.0
|
1.0
|
H22
|
A:DG3
|
4.8
|
0.0
|
1.0
|
C3'
|
A:DA7
|
4.8
|
0.0
|
1.0
|
C2'
|
A:BGM2
|
4.8
|
0.0
|
1.0
|
H1
|
A:BGM8
|
4.8
|
0.0
|
1.0
|
C1'
|
A:DA7
|
4.9
|
0.0
|
1.0
|
H4'
|
A:DA1
|
5.0
|
0.0
|
1.0
|
|
Bromine binding site 2 out
of 5 in 2e4i
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Bromine Binding Sites List in 2e4i
Bromine binding site 2 out
of 5 in the Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines
Mono view
Stereo pair view
|
A full contact list of Bromine with other atoms in the Br binding
site number 2 of Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Br8
b:0.0
occ:1.00
|
BR
|
A:BGM8
|
0.0
|
0.0
|
1.0
|
C8
|
A:BGM8
|
1.9
|
0.0
|
1.0
|
H1'
|
A:BGM8
|
2.8
|
0.0
|
1.0
|
N7
|
A:BGM8
|
2.8
|
0.0
|
1.0
|
H3
|
A:DT17
|
2.9
|
0.0
|
1.0
|
N9
|
A:BGM8
|
2.9
|
0.0
|
1.0
|
C1'
|
A:BGM8
|
3.4
|
0.0
|
1.0
|
O4'
|
A:DG9
|
3.4
|
0.0
|
1.0
|
H22
|
A:DG16
|
3.4
|
0.0
|
1.0
|
H1'
|
A:DG9
|
3.4
|
0.0
|
1.0
|
H21
|
A:DG16
|
3.5
|
0.0
|
1.0
|
N2
|
A:DG16
|
3.8
|
0.0
|
1.0
|
N3
|
A:DT17
|
3.8
|
0.0
|
1.0
|
C1'
|
A:DG9
|
3.8
|
0.0
|
1.0
|
C5
|
A:BGM8
|
4.0
|
0.0
|
1.0
|
H4'
|
A:DG9
|
4.0
|
0.0
|
1.0
|
O4'
|
A:BGM8
|
4.1
|
0.0
|
1.0
|
C4
|
A:BGM8
|
4.1
|
0.0
|
1.0
|
O5'
|
A:DG9
|
4.1
|
0.0
|
1.0
|
N9
|
A:DG9
|
4.1
|
0.0
|
1.0
|
O2
|
A:DT17
|
4.2
|
0.0
|
1.0
|
C4'
|
A:DG9
|
4.2
|
0.0
|
1.0
|
C2
|
A:DT17
|
4.4
|
0.0
|
1.0
|
OP1
|
A:DG9
|
4.4
|
0.0
|
1.0
|
C4
|
A:DG9
|
4.6
|
0.0
|
1.0
|
O4
|
A:DT17
|
4.6
|
0.0
|
1.0
|
C2'
|
A:BGM8
|
4.7
|
0.0
|
1.0
|
C4
|
A:DT17
|
4.7
|
0.0
|
1.0
|
H2''
|
A:BGM8
|
4.7
|
0.0
|
1.0
|
N3
|
A:DG9
|
4.7
|
0.0
|
1.0
|
C8
|
A:DG9
|
4.7
|
0.0
|
1.0
|
C5'
|
A:DG9
|
4.8
|
0.0
|
1.0
|
OP1
|
A:DG10
|
4.8
|
0.0
|
1.0
|
H8
|
A:DG9
|
5.0
|
0.0
|
1.0
|
P
|
A:DG9
|
5.0
|
0.0
|
1.0
|
|
Bromine binding site 3 out
of 5 in 2e4i
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Bromine Binding Sites List in 2e4i
Bromine binding site 3 out
of 5 in the Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines
Mono view
Stereo pair view
|
A full contact list of Bromine with other atoms in the Br binding
site number 3 of Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Br14
b:0.0
occ:1.00
|
BR
|
A:BGM14
|
0.0
|
0.0
|
1.0
|
C8
|
A:BGM14
|
1.9
|
0.0
|
1.0
|
H1'
|
A:BGM14
|
2.8
|
0.0
|
1.0
|
N7
|
A:BGM14
|
2.8
|
0.0
|
1.0
|
N9
|
A:BGM14
|
2.9
|
0.0
|
1.0
|
C1'
|
A:BGM14
|
3.4
|
0.0
|
1.0
|
O4'
|
A:BGM15
|
3.4
|
0.0
|
1.0
|
H22
|
A:DG10
|
3.8
|
0.0
|
1.0
|
H21
|
A:DG10
|
3.9
|
0.0
|
1.0
|
H1'
|
A:BGM15
|
3.9
|
0.0
|
1.0
|
O4'
|
A:BGM14
|
4.0
|
0.0
|
1.0
|
C5
|
A:BGM14
|
4.0
|
0.0
|
1.0
|
N9
|
A:BGM15
|
4.0
|
0.0
|
1.0
|
C1'
|
A:BGM15
|
4.0
|
0.0
|
1.0
|
C4
|
A:BGM14
|
4.1
|
0.0
|
1.0
|
N2
|
A:DG10
|
4.2
|
0.0
|
1.0
|
C4
|
A:BGM15
|
4.3
|
0.0
|
1.0
|
C8
|
A:BGM15
|
4.4
|
0.0
|
1.0
|
H4'
|
A:BGM15
|
4.5
|
0.0
|
1.0
|
C4'
|
A:BGM15
|
4.5
|
0.0
|
1.0
|
H8
|
A:DA13
|
4.6
|
0.0
|
1.0
|
N3
|
A:BGM15
|
4.6
|
0.0
|
1.0
|
O5'
|
A:BGM15
|
4.7
|
0.0
|
1.0
|
C2'
|
A:BGM14
|
4.7
|
0.0
|
1.0
|
C5
|
A:BGM15
|
4.8
|
0.0
|
1.0
|
H2''
|
A:BGM14
|
4.8
|
0.0
|
1.0
|
N7
|
A:BGM15
|
4.9
|
0.0
|
1.0
|
|
Bromine binding site 4 out
of 5 in 2e4i
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Bromine Binding Sites List in 2e4i
Bromine binding site 4 out
of 5 in the Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines
Mono view
Stereo pair view
|
A full contact list of Bromine with other atoms in the Br binding
site number 4 of Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Br15
b:0.0
occ:1.00
|
BR
|
A:BGM15
|
0.0
|
0.0
|
1.0
|
C8
|
A:BGM15
|
1.9
|
0.0
|
1.0
|
H1'
|
A:BGM15
|
2.8
|
0.0
|
1.0
|
N7
|
A:BGM15
|
2.8
|
0.0
|
1.0
|
N9
|
A:BGM15
|
2.9
|
0.0
|
1.0
|
H5'
|
A:DG16
|
2.9
|
0.0
|
1.0
|
O4'
|
A:DG16
|
2.9
|
0.0
|
1.0
|
H73
|
A:DT17
|
3.1
|
0.0
|
1.0
|
C1'
|
A:BGM15
|
3.3
|
0.0
|
1.0
|
C5'
|
A:DG16
|
3.8
|
0.0
|
1.0
|
C4'
|
A:DG16
|
3.8
|
0.0
|
1.0
|
H2''
|
A:BGM15
|
3.9
|
0.0
|
1.0
|
H22
|
A:DG9
|
3.9
|
0.0
|
1.0
|
H21
|
A:DG9
|
4.0
|
0.0
|
1.0
|
C5
|
A:BGM15
|
4.0
|
0.0
|
1.0
|
H4'
|
A:DG16
|
4.0
|
0.0
|
1.0
|
C7
|
A:DT17
|
4.0
|
0.0
|
1.0
|
C4
|
A:BGM15
|
4.1
|
0.0
|
1.0
|
C1'
|
A:DG16
|
4.1
|
0.0
|
1.0
|
H71
|
A:DT17
|
4.1
|
0.0
|
1.0
|
N9
|
A:DG16
|
4.1
|
0.0
|
1.0
|
C2'
|
A:BGM15
|
4.2
|
0.0
|
1.0
|
N2
|
A:DG9
|
4.3
|
0.0
|
1.0
|
H1'
|
A:DG16
|
4.4
|
0.0
|
1.0
|
C8
|
A:DG16
|
4.5
|
0.0
|
1.0
|
O5'
|
A:DG16
|
4.5
|
0.0
|
1.0
|
O4'
|
A:BGM15
|
4.6
|
0.0
|
1.0
|
C4
|
A:DG16
|
4.6
|
0.0
|
1.0
|
H5''
|
A:DG16
|
4.6
|
0.0
|
1.0
|
H72
|
A:DT17
|
4.6
|
0.0
|
1.0
|
H8
|
A:DG16
|
4.7
|
0.0
|
1.0
|
H2'
|
A:BGM15
|
4.7
|
0.0
|
1.0
|
H22
|
A:DG10
|
4.8
|
0.0
|
1.0
|
N3
|
A:DG16
|
5.0
|
0.0
|
1.0
|
N2
|
A:DG10
|
5.0
|
0.0
|
1.0
|
H21
|
A:DG10
|
5.0
|
0.0
|
1.0
|
|
Bromine binding site 5 out
of 5 in 2e4i
Go back to
Bromine Binding Sites List in 2e4i
Bromine binding site 5 out
of 5 in the Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines
Mono view
Stereo pair view
|
A full contact list of Bromine with other atoms in the Br binding
site number 5 of Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Br20
b:0.0
occ:1.00
|
BR
|
A:BGM20
|
0.0
|
0.0
|
1.0
|
C8
|
A:BGM20
|
1.9
|
0.0
|
1.0
|
H1'
|
A:BGM20
|
2.8
|
0.0
|
1.0
|
N7
|
A:BGM20
|
2.8
|
0.0
|
1.0
|
N9
|
A:BGM20
|
2.9
|
0.0
|
1.0
|
C1'
|
A:BGM20
|
3.4
|
0.0
|
1.0
|
O4'
|
A:DG21
|
3.8
|
0.0
|
1.0
|
H21
|
A:BGM2
|
3.8
|
0.0
|
1.0
|
H22
|
A:BGM2
|
3.9
|
0.0
|
1.0
|
C5
|
A:BGM20
|
4.0
|
0.0
|
1.0
|
C4
|
A:BGM20
|
4.1
|
0.0
|
1.0
|
H2
|
A:DA1
|
4.1
|
0.0
|
1.0
|
O4'
|
A:BGM20
|
4.1
|
0.0
|
1.0
|
H5'
|
A:DG21
|
4.2
|
0.0
|
1.0
|
N2
|
A:BGM2
|
4.2
|
0.0
|
1.0
|
N3
|
A:DG21
|
4.3
|
0.0
|
1.0
|
C4
|
A:DG21
|
4.4
|
0.0
|
1.0
|
O5'
|
A:DG21
|
4.5
|
0.0
|
1.0
|
OP1
|
A:DG21
|
4.5
|
0.0
|
1.0
|
C2'
|
A:BGM20
|
4.6
|
0.0
|
1.0
|
H2''
|
A:BGM20
|
4.6
|
0.0
|
1.0
|
N9
|
A:DG21
|
4.6
|
0.0
|
1.0
|
C5'
|
A:DG21
|
4.7
|
0.0
|
1.0
|
C4'
|
A:DG21
|
4.7
|
0.0
|
1.0
|
C2
|
A:DG21
|
4.8
|
0.0
|
1.0
|
C1'
|
A:DG21
|
4.8
|
0.0
|
1.0
|
H4'
|
A:DG21
|
4.9
|
0.0
|
1.0
|
C2
|
A:DA1
|
4.9
|
0.0
|
1.0
|
N3
|
A:DA1
|
5.0
|
0.0
|
1.0
|
|
Reference:
A.Matsugami,
Y.Xu,
Y.Noguchi,
H.Sugiyama,
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ISSN: ISSN 1742-464X
PubMed: 17561958
DOI: 10.1111/J.1742-4658.2007.05881.X
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