Bromine in PDB 2e4i: Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines

The binding sites of Bromine atom in the Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines (pdb code 2e4i). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 5 binding sites of Bromine where determined in the Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines, PDB code: 2e4i:
Jump to Bromine binding site number: 1; 2; 3; 4; 5;

Bromine binding site 1 out of 5 in the Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines within 5.0Å range: probe atom residue distance (Å) B Occ A:Br2 b:0.0 occ:1.00 BR A:BGM2 0.0 0.0 1.0 C8 A:BGM2 1.9 0.0 1.0 H4' A:DA7 2.8 0.0 1.0 N7 A:BGM2 2.8 0.0 1.0 H1' A:BGM2 2.9 0.0 1.0 N9 A:BGM2 2.9 0.0 1.0 H5'' A:DA7 2.9 0.0 1.0 H5' A:DA7 2.9 0.0 1.0 O4 A:DT5 2.9 0.0 1.0 C5' A:DA7 3.2 0.0 1.0 H22 A:BGM8 3.2 0.0 1.0 C4' A:DA7 3.3 0.0 1.0 C1' A:BGM2 3.3 0.0 1.0 O4' A:DA7 3.5 0.0 1.0 O4' A:BGM2 3.7 0.0 1.0 C4 A:DT5 3.8 0.0 1.0 HO5' A:DA1 3.9 0.0 1.0 C5 A:BGM2 4.0 0.0 1.0 N2 A:BGM8 4.0 0.0 1.0 C4 A:BGM2 4.0 0.0 1.0 H21 A:BGM8 4.1 0.0 1.0 H72 A:DT5 4.2 0.0 1.0 O5' A:DA1 4.3 0.0 1.0 H73 A:DT5 4.3 0.0 1.0 H1' A:DG3 4.3 0.0 1.0 H3 A:DT5 4.4 0.0 1.0 N3 A:DT5 4.5 0.0 1.0 C7 A:DT5 4.6 0.0 1.0 C5 A:DT5 4.6 0.0 1.0 O5' A:DA7 4.6 0.0 1.0 N3 A:DG3 4.6 0.0 1.0 H22 A:DG3 4.8 0.0 1.0 C3' A:DA7 4.8 0.0 1.0 C2' A:BGM2 4.8 0.0 1.0 H1 A:BGM8 4.8 0.0 1.0 C1' A:DA7 4.9 0.0 1.0 H4' A:DA1 5.0 0.0 1.0

Bromine binding site 2 out of 5 in the Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines within 5.0Å range: probe atom residue distance (Å) B Occ A:Br8 b:0.0 occ:1.00 BR A:BGM8 0.0 0.0 1.0 C8 A:BGM8 1.9 0.0 1.0 H1' A:BGM8 2.8 0.0 1.0 N7 A:BGM8 2.8 0.0 1.0 H3 A:DT17 2.9 0.0 1.0 N9 A:BGM8 2.9 0.0 1.0 C1' A:BGM8 3.4 0.0 1.0 O4' A:DG9 3.4 0.0 1.0 H22 A:DG16 3.4 0.0 1.0 H1' A:DG9 3.4 0.0 1.0 H21 A:DG16 3.5 0.0 1.0 N2 A:DG16 3.8 0.0 1.0 N3 A:DT17 3.8 0.0 1.0 C1' A:DG9 3.8 0.0 1.0 C5 A:BGM8 4.0 0.0 1.0 H4' A:DG9 4.0 0.0 1.0 O4' A:BGM8 4.1 0.0 1.0 C4 A:BGM8 4.1 0.0 1.0 O5' A:DG9 4.1 0.0 1.0 N9 A:DG9 4.1 0.0 1.0 O2 A:DT17 4.2 0.0 1.0 C4' A:DG9 4.2 0.0 1.0 C2 A:DT17 4.4 0.0 1.0 OP1 A:DG9 4.4 0.0 1.0 C4 A:DG9 4.6 0.0 1.0 O4 A:DT17 4.6 0.0 1.0 C2' A:BGM8 4.7 0.0 1.0 C4 A:DT17 4.7 0.0 1.0 H2'' A:BGM8 4.7 0.0 1.0 N3 A:DG9 4.7 0.0 1.0 C8 A:DG9 4.7 0.0 1.0 C5' A:DG9 4.8 0.0 1.0 OP1 A:DG10 4.8 0.0 1.0 H8 A:DG9 5.0 0.0 1.0 P A:DG9 5.0 0.0 1.0

Bromine binding site 3 out of 5 in the Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 3 of Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines within 5.0Å range: probe atom residue distance (Å) B Occ A:Br14 b:0.0 occ:1.00 BR A:BGM14 0.0 0.0 1.0 C8 A:BGM14 1.9 0.0 1.0 H1' A:BGM14 2.8 0.0 1.0 N7 A:BGM14 2.8 0.0 1.0 N9 A:BGM14 2.9 0.0 1.0 C1' A:BGM14 3.4 0.0 1.0 O4' A:BGM15 3.4 0.0 1.0 H22 A:DG10 3.8 0.0 1.0 H21 A:DG10 3.9 0.0 1.0 H1' A:BGM15 3.9 0.0 1.0 O4' A:BGM14 4.0 0.0 1.0 C5 A:BGM14 4.0 0.0 1.0 N9 A:BGM15 4.0 0.0 1.0 C1' A:BGM15 4.0 0.0 1.0 C4 A:BGM14 4.1 0.0 1.0 N2 A:DG10 4.2 0.0 1.0 C4 A:BGM15 4.3 0.0 1.0 C8 A:BGM15 4.4 0.0 1.0 H4' A:BGM15 4.5 0.0 1.0 C4' A:BGM15 4.5 0.0 1.0 H8 A:DA13 4.6 0.0 1.0 N3 A:BGM15 4.6 0.0 1.0 O5' A:BGM15 4.7 0.0 1.0 C2' A:BGM14 4.7 0.0 1.0 C5 A:BGM15 4.8 0.0 1.0 H2'' A:BGM14 4.8 0.0 1.0 N7 A:BGM15 4.9 0.0 1.0

Bromine binding site 4 out of 5 in the Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 4 of Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines within 5.0Å range: probe atom residue distance (Å) B Occ A:Br15 b:0.0 occ:1.00 BR A:BGM15 0.0 0.0 1.0 C8 A:BGM15 1.9 0.0 1.0 H1' A:BGM15 2.8 0.0 1.0 N7 A:BGM15 2.8 0.0 1.0 N9 A:BGM15 2.9 0.0 1.0 H5' A:DG16 2.9 0.0 1.0 O4' A:DG16 2.9 0.0 1.0 H73 A:DT17 3.1 0.0 1.0 C1' A:BGM15 3.3 0.0 1.0 C5' A:DG16 3.8 0.0 1.0 C4' A:DG16 3.8 0.0 1.0 H2'' A:BGM15 3.9 0.0 1.0 H22 A:DG9 3.9 0.0 1.0 H21 A:DG9 4.0 0.0 1.0 C5 A:BGM15 4.0 0.0 1.0 H4' A:DG16 4.0 0.0 1.0 C7 A:DT17 4.0 0.0 1.0 C4 A:BGM15 4.1 0.0 1.0 C1' A:DG16 4.1 0.0 1.0 H71 A:DT17 4.1 0.0 1.0 N9 A:DG16 4.1 0.0 1.0 C2' A:BGM15 4.2 0.0 1.0 N2 A:DG9 4.3 0.0 1.0 H1' A:DG16 4.4 0.0 1.0 C8 A:DG16 4.5 0.0 1.0 O5' A:DG16 4.5 0.0 1.0 O4' A:BGM15 4.6 0.0 1.0 C4 A:DG16 4.6 0.0 1.0 H5'' A:DG16 4.6 0.0 1.0 H72 A:DT17 4.6 0.0 1.0 H8 A:DG16 4.7 0.0 1.0 H2' A:BGM15 4.7 0.0 1.0 H22 A:DG10 4.8 0.0 1.0 N3 A:DG16 5.0 0.0 1.0 N2 A:DG10 5.0 0.0 1.0 H21 A:DG10 5.0 0.0 1.0

Bromine binding site 5 out of 5 in the Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 5 of Human Telomeric Dna Mixed-Parallel/Antiparallel Quadruplex Under Physiological Ionic Conditions Stabilized By Proper Incorporation of 8-Bromoguanosines within 5.0Å range: probe atom residue distance (Å) B Occ A:Br20 b:0.0 occ:1.00 BR A:BGM20 0.0 0.0 1.0 C8 A:BGM20 1.9 0.0 1.0 H1' A:BGM20 2.8 0.0 1.0 N7 A:BGM20 2.8 0.0 1.0 N9 A:BGM20 2.9 0.0 1.0 C1' A:BGM20 3.4 0.0 1.0 O4' A:DG21 3.8 0.0 1.0 H21 A:BGM2 3.8 0.0 1.0 H22 A:BGM2 3.9 0.0 1.0 C5 A:BGM20 4.0 0.0 1.0 C4 A:BGM20 4.1 0.0 1.0 H2 A:DA1 4.1 0.0 1.0 O4' A:BGM20 4.1 0.0 1.0 H5' A:DG21 4.2 0.0 1.0 N2 A:BGM2 4.2 0.0 1.0 N3 A:DG21 4.3 0.0 1.0 C4 A:DG21 4.4 0.0 1.0 O5' A:DG21 4.5 0.0 1.0 OP1 A:DG21 4.5 0.0 1.0 C2' A:BGM20 4.6 0.0 1.0 H2'' A:BGM20 4.6 0.0 1.0 N9 A:DG21 4.6 0.0 1.0 C5' A:DG21 4.7 0.0 1.0 C4' A:DG21 4.7 0.0 1.0 C2 A:DG21 4.8 0.0 1.0 C1' A:DG21 4.8 0.0 1.0 H4' A:DG21 4.9 0.0 1.0 C2 A:DA1 4.9 0.0 1.0 N3 A:DA1 5.0 0.0 1.0

A.Matsugami, Y.Xu, Y.Noguchi, H.Sugiyama, M.Katahira. Structure of A Human Telomeric Dna Sequence Stabilized By 8-Bromoguanosine Substitutions, As Determined By uc(Nmr) in A K+ Solution Febs J. V. 274 3545 2007.
ISSN: ISSN 1742-464X
PubMed: 17561958
DOI: 10.1111/J.1742-4658.2007.05881.X