Bromine in PDB 2ja6: Cpd Lesion Containing Rna Polymerase II Elongation Complex B

All present enzymatic activity of Cpd Lesion Containing Rna Polymerase II Elongation Complex B:
2.7.7.6;

The structure of Cpd Lesion Containing Rna Polymerase II Elongation Complex B, PDB code: 2ja6 was solved by F.Brueckner, U.Hennecke, T.Carell, P.Cramer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 4.00
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	223.580, 393.491, 283.505, 90.00, 90.00, 90.00
R / Rfree (%)	29.2 / 30.1

The structure of Cpd Lesion Containing Rna Polymerase II Elongation Complex B also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Zinc	(Zn)	8 atoms

The binding sites of Bromine atom in the Cpd Lesion Containing Rna Polymerase II Elongation Complex B (pdb code 2ja6). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Cpd Lesion Containing Rna Polymerase II Elongation Complex B, PDB code: 2ja6:

Bromine binding site 1 out of 1 in the Cpd Lesion Containing Rna Polymerase II Elongation Complex B


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Cpd Lesion Containing Rna Polymerase II Elongation Complex B within 5.0Å range: probe atom residue distance (Å) B Occ T:Br22 b:0.3 occ:1.00 BR T:BRU22 0.0 0.3 1.0 C5 T:BRU22 1.9 0.0 1.0 C6 T:BRU22 2.8 0.9 1.0 C4 T:BRU22 2.9 0.1 1.0 O4 T:BRU22 3.1 0.9 1.0 C5 T:DC21 3.4 0.2 1.0 C6 T:DC21 3.6 0.4 1.0 OP2 T:BRU22 4.0 0.9 1.0 C4 T:DC21 4.1 0.5 1.0 N3 T:BRU22 4.1 0.9 1.0 N1 T:BRU22 4.2 0.7 1.0 N1 T:DC21 4.3 0.9 1.0 C3' T:DC21 4.3 0.5 1.0 N7 T:DG23 4.6 0.3 1.0 C2' T:DC21 4.6 0.5 1.0 N4 T:DC21 4.6 0.8 1.0 N3 T:DC21 4.7 0.3 1.0 C2 T:BRU22 4.7 0.8 1.0 C2 T:DC21 4.8 0.3 1.0 P T:BRU22 5.0 0.7 1.0

F.Brueckner, U.Hennecke, T.Carell, P.Cramer. Cpd Damage Recognition By Transcribing Rna Polymerase II. Science V. 315 859 2007.
ISSN: ESSN 1095-9203
PubMed: 17290000
DOI: 10.1126/SCIENCE.1135400