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Atomistry » Bromine » PDB 2jlt-2qbs » 2pev » |
Bromine in PDB 2pev: Complex of Aldose Reductase with Nadp+ and Simaltaneously Bound Competetive Inhibitors Fidarestat and IDD594. Concentration of Fidarestat in Soaking Solution Exceeds Concentration of IDD594.Enzymatic activity of Complex of Aldose Reductase with Nadp+ and Simaltaneously Bound Competetive Inhibitors Fidarestat and IDD594. Concentration of Fidarestat in Soaking Solution Exceeds Concentration of IDD594.
All present enzymatic activity of Complex of Aldose Reductase with Nadp+ and Simaltaneously Bound Competetive Inhibitors Fidarestat and IDD594. Concentration of Fidarestat in Soaking Solution Exceeds Concentration of IDD594.:
1.1.1.21; Protein crystallography data
The structure of Complex of Aldose Reductase with Nadp+ and Simaltaneously Bound Competetive Inhibitors Fidarestat and IDD594. Concentration of Fidarestat in Soaking Solution Exceeds Concentration of IDD594., PDB code: 2pev
was solved by
T.Petrova,
I.Hazemann,
A.Cousido,
A.Mitschler,
S.Ginell,
A.Joachimiak,
A.Podjarny,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2pev:
The structure of Complex of Aldose Reductase with Nadp+ and Simaltaneously Bound Competetive Inhibitors Fidarestat and IDD594. Concentration of Fidarestat in Soaking Solution Exceeds Concentration of IDD594. also contains other interesting chemical elements:
Bromine Binding Sites:
The binding sites of Bromine atom in the Complex of Aldose Reductase with Nadp+ and Simaltaneously Bound Competetive Inhibitors Fidarestat and IDD594. Concentration of Fidarestat in Soaking Solution Exceeds Concentration of IDD594.
(pdb code 2pev). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Complex of Aldose Reductase with Nadp+ and Simaltaneously Bound Competetive Inhibitors Fidarestat and IDD594. Concentration of Fidarestat in Soaking Solution Exceeds Concentration of IDD594., PDB code: 2pev: Bromine binding site 1 out of 1 in 2pevGo back to Bromine Binding Sites List in 2pev
Bromine binding site 1 out
of 1 in the Complex of Aldose Reductase with Nadp+ and Simaltaneously Bound Competetive Inhibitors Fidarestat and IDD594. Concentration of Fidarestat in Soaking Solution Exceeds Concentration of IDD594.
Mono view Stereo pair view
Reference:
A.Cousido-Siah,
T.Petrova,
I.Hazemann,
A.Mitschler,
F.X.Ruiz,
E.Howard,
S.Ginell,
C.Atmanene,
A.Van Dorsselaer,
S.Sanglier-Cianferani,
A.Joachimiak,
A.Podjarny.
Crystal Packing Modifies Ligand Binding Affinity: the Case of Aldose Reductase. Proteins V. 80 2552 2012.
Page generated: Sat Dec 12 02:07:27 2020
ISSN: ISSN 0887-3585 PubMed: 22752989 DOI: 10.1002/PROT.24136 |
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