Bromine in PDB 2pf8: Complex of Aldose Reductase with Nadp+ and Simaltaneously Bound Competetive Inhibitors Fidarestat and IDD594. Concentration of Fidarestat in Soaking Solution Is Equal to Concentration of IDD594.

Enzymatic activity of Complex of Aldose Reductase with Nadp+ and Simaltaneously Bound Competetive Inhibitors Fidarestat and IDD594. Concentration of Fidarestat in Soaking Solution Is Equal to Concentration of IDD594.

Protein crystallography data

Other elements in 2pf8:

Bromine Binding Sites:

Bromine binding site 1 out of 1 in 2pf8

Bromine Binding Sites List in 2pf8

Bromine binding site 1 out of 1 in the Complex of Aldose Reductase with Nadp+ and Simaltaneously Bound Competetive Inhibitors Fidarestat and IDD594. Concentration of Fidarestat in Soaking Solution Is Equal to Concentration of IDD594.


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Complex of Aldose Reductase with Nadp+ and Simaltaneously Bound Competetive Inhibitors Fidarestat and IDD594. Concentration of Fidarestat in Soaking Solution Is Equal to Concentration of IDD594. within 5.0Å range: probe atom residue distance (Å) B Occ A:Br320 b:5.4 occ:0.60 BR8 A:LDT320 0.0 5.4 0.6 CD2 A:LEU300 1.0 8.9 0.4 C25 A:LDT320 1.9 4.7 0.6 CG A:LEU300 2.5 8.1 0.4 C29 A:LDT320 2.8 4.8 0.6 C28 A:LDT320 2.8 4.8 0.6 OG1 A:THR113 2.9 6.1 1.0 CD1 A:LEU300 3.1 10.2 0.4 CB A:LEU300 3.6 7.4 0.4 SG A:CYS303 3.8 10.2 0.4 CE3 A:TRP111 3.8 5.3 1.0 CB A:CYS303 3.8 9.7 0.4 CD2 A:TRP111 3.9 5.2 1.0 CG A:TRP111 3.9 5.3 1.0 CZ A:PHE115 3.9 6.0 1.0 CB A:CYS303 4.0 6.4 0.6 CB A:TRP111 4.0 5.3 1.0 CB A:THR113 4.0 5.8 1.0 CG2 A:THR113 4.0 6.7 1.0 SG A:CYS303 4.1 6.7 0.6 C27 A:LDT320 4.1 4.7 0.6 C26 A:LDT320 4.1 4.6 0.6 CE1 A:PHE115 4.2 6.2 1.0 CD1 A:TYR309 4.4 5.9 0.6 CZ3 A:TRP111 4.6 5.7 1.0 CE1 A:TYR309 4.6 6.1 0.6 CE2 A:TRP111 4.7 5.6 1.0 C24 A:LDT320 4.7 4.7 0.6 CD1 A:TRP111 4.7 5.8 1.0 SG A:CYS80 4.7 4.7 1.0 CA A:LEU300 5.0 8.1 0.4

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