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Atomistry » Bromine » PDB 2qc6-2vo5 » 2qq7 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Bromine » PDB 2qc6-2vo5 » 2qq7 » |
Bromine in PDB 2qq7: Crystal Structure of Drug Resistant Src Kinase Domain with Irreversible InhibitorEnzymatic activity of Crystal Structure of Drug Resistant Src Kinase Domain with Irreversible Inhibitor
All present enzymatic activity of Crystal Structure of Drug Resistant Src Kinase Domain with Irreversible Inhibitor:
2.7.10.2; Protein crystallography data
The structure of Crystal Structure of Drug Resistant Src Kinase Domain with Irreversible Inhibitor, PDB code: 2qq7
was solved by
A.Michalczyk,
H.B.Rode,
C.Gruetter,
D.Rauh,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of Drug Resistant Src Kinase Domain with Irreversible Inhibitor
(pdb code 2qq7). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Crystal Structure of Drug Resistant Src Kinase Domain with Irreversible Inhibitor, PDB code: 2qq7: Jump to Bromine binding site number: 1; 2; Bromine binding site 1 out of 2 in 2qq7Go back to Bromine Binding Sites List in 2qq7
Bromine binding site 1 out
of 2 in the Crystal Structure of Drug Resistant Src Kinase Domain with Irreversible Inhibitor
Mono view Stereo pair view
Bromine binding site 2 out of 2 in 2qq7Go back to Bromine Binding Sites List in 2qq7
Bromine binding site 2 out
of 2 in the Crystal Structure of Drug Resistant Src Kinase Domain with Irreversible Inhibitor
Mono view Stereo pair view
Reference:
A.Michalczyk,
S.Kluter,
H.B.Rode,
J.R.Simard,
C.Grutter,
M.Rabiller,
D.Rauh.
Structural Insights Into How Irreversible Inhibitors Can Overcome Drug Resistance in Egfr. Bioorg.Med.Chem. V. 16 3482 2008.
Page generated: Sat Dec 12 02:08:01 2020
ISSN: ISSN 0968-0896 PubMed: 18316192 DOI: 10.1016/J.BMC.2008.02.053 |
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