Bromine in PDB 2v6q: Crystal Structure of A Bhrf-1 : Bim BH3 Complex

The structure of Crystal Structure of A Bhrf-1 : Bim BH3 Complex, PDB code: 2v6q was solved by M.Kvansakul, D.C.S.Huang, P.M.Colman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.22 / 2.70
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	62.736, 62.736, 92.523, 90.00, 90.00, 120.00
R / Rfree (%)	20.6 / 24.9

The binding sites of Bromine atom in the Crystal Structure of A Bhrf-1 : Bim BH3 Complex (pdb code 2v6q). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 5 binding sites of Bromine where determined in the Crystal Structure of A Bhrf-1 : Bim BH3 Complex, PDB code: 2v6q:
Jump to Bromine binding site number: 1; 2; 3; 4; 5;

Bromine binding site 1 out of 5 in the Crystal Structure of A Bhrf-1 : Bim BH3 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of A Bhrf-1 : Bim BH3 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br1157 b:58.2 occ:1.00 O A:GLU77 3.4 42.1 1.0 N A:VAL79 3.5 34.2 1.0 CG2 A:VAL79 3.6 31.9 1.0 CD1 A:LEU128 3.7 18.5 1.0 CA A:HIS78 3.7 38.1 1.0 C A:GLU77 3.9 41.8 1.0 C A:HIS78 4.1 36.0 1.0 CE2 A:TYR124 4.2 24.7 1.0 N A:HIS78 4.2 39.9 1.0 CB A:VAL79 4.3 30.9 1.0 CA A:VAL79 4.5 31.7 1.0 CD2 A:TYR124 4.6 24.1 1.0 CB A:HIS78 4.9 39.0 1.0 CG A:LEU128 5.0 17.8 1.0

Bromine binding site 2 out of 5 in the Crystal Structure of A Bhrf-1 : Bim BH3 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Crystal Structure of A Bhrf-1 : Bim BH3 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br1158 b:46.5 occ:1.00 CB A:SER62 3.4 23.9 1.0 OG A:SER62 3.5 22.3 1.0 O A:ILE58 3.9 27.9 1.0 CG2 A:ILE58 4.0 25.0 1.0 CG A:GLU59 4.1 31.4 1.0 CA A:SER62 4.1 23.9 1.0 CA A:GLU59 4.3 29.0 1.0 C A:ILE58 4.4 27.1 1.0 N A:GLU59 4.6 28.1 1.0 CB A:GLU59 4.8 29.3 1.0 OE2 A:GLU55 4.9 30.5 1.0

Bromine binding site 3 out of 5 in the Crystal Structure of A Bhrf-1 : Bim BH3 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 3 of Crystal Structure of A Bhrf-1 : Bim BH3 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br1159 b:90.6 occ:1.00 OG A:SER41 3.2 40.0 1.0 CB A:SER41 3.6 40.6 1.0 CD A:PRO42 3.9 39.5 1.0 CA A:SER41 4.1 39.9 1.0 CG A:PRO42 4.7 39.6 1.0 N A:PRO42 4.7 39.2 1.0 C A:SER41 4.9 39.4 1.0

Bromine binding site 4 out of 5 in the Crystal Structure of A Bhrf-1 : Bim BH3 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 4 of Crystal Structure of A Bhrf-1 : Bim BH3 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br1160 b:83.5 occ:1.00 NH1 A:ARG60 2.3 39.8 1.0 OD1 A:ASN61 3.3 26.5 1.0 CZ A:ARG60 3.6 41.0 1.0 CG2 B:ILE65 3.7 38.8 1.0 CD A:ARG60 4.0 37.4 1.0 CG A:ASN61 4.2 24.2 1.0 CG1 A:ILE57 4.2 27.9 1.0 CG2 A:ILE57 4.2 26.3 1.0 NE A:ARG60 4.2 40.6 1.0 ND2 A:ASN61 4.3 22.8 1.0 O B:ILE65 4.3 42.2 1.0 CB A:ARG60 4.3 29.3 1.0 CB B:PHE69 4.4 56.1 1.0 CD1 B:PHE69 4.5 53.9 1.0 CA A:ILE57 4.5 27.1 1.0 CB A:ILE57 4.6 27.2 1.0 NH2 A:ARG60 4.6 44.0 1.0 CA B:PHE69 4.7 57.7 1.0 N B:PHE69 4.7 56.8 1.0 O A:ILE57 4.7 25.6 1.0 CG A:ARG60 4.9 32.2 1.0 CB B:ILE65 4.9 39.5 1.0 CB B:GLU68 5.0 55.0 1.0 CG B:PHE69 5.0 55.1 1.0

Bromine binding site 5 out of 5 in the Crystal Structure of A Bhrf-1 : Bim BH3 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 5 of Crystal Structure of A Bhrf-1 : Bim BH3 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br1161 b:89.4 occ:1.00 ND1 A:HIS92 4.3 62.1 1.0 CE1 A:HIS92 4.5 62.8 1.0 O A:HOH2014 4.6 32.6 1.0 CG A:HIS92 4.7 59.1 1.0 NE2 A:HIS92 4.9 61.9 1.0

M.Kvansakul, A.H.Wei, J.I.Fletcher, S.N.Willis, L.Chen, A.W.Roberts, D.C.Huang, P.M.Colman. Structural Basis For Apoptosis Inhibition By Epstein-Barr Virus BHRF1. Plos Pathog. V. 6 1236 2010.
ISSN: ISSN 1553-7366
PubMed: 21203485
DOI: 10.1371/JOURNAL.PPAT.1001236