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Atomistry » Bromine » PDB 2vot-2xo8 » 2xag | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Bromine » PDB 2vot-2xo8 » 2xag » |
Bromine in PDB 2xag: Crystal Structure of LSD1-Corest in Complex with Para-Bromo- (-)-Trans-2-Phenylcyclopropyl-1-AmineProtein crystallography data
The structure of Crystal Structure of LSD1-Corest in Complex with Para-Bromo- (-)-Trans-2-Phenylcyclopropyl-1-Amine, PDB code: 2xag
was solved by
C.Binda,
S.Valente,
M.Romanenghi,
S.Pilotto,
R.Cirilli,
A.Karytinos,
G.Ciossani,
O.A.Botrugno,
F.Forneris,
M.Tardugno,
D.E.Edmondson,
S.Minucci,
A.Mattevi,
A.Mai,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of LSD1-Corest in Complex with Para-Bromo- (-)-Trans-2-Phenylcyclopropyl-1-Amine
(pdb code 2xag). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of LSD1-Corest in Complex with Para-Bromo- (-)-Trans-2-Phenylcyclopropyl-1-Amine, PDB code: 2xag: Bromine binding site 1 out of 1 in 2xagGo back to Bromine Binding Sites List in 2xag
Bromine binding site 1 out
of 1 in the Crystal Structure of LSD1-Corest in Complex with Para-Bromo- (-)-Trans-2-Phenylcyclopropyl-1-Amine
Mono view Stereo pair view
Reference:
C.Binda,
S.Valente,
M.Romanenghi,
S.Pilotto,
R.Cirilli,
A.Karytinos,
G.Ciossani,
O.A.Botrugno,
F.Forneris,
M.Tardugno,
D.E.Edmondson,
S.Minucci,
A.Mattevi,
A.Mai.
Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives As Inhibitors of Histone Demethylases LSD1 and LSD2. J.Am.Chem.Soc. V. 132 6827 2010.
Page generated: Sat Dec 12 02:09:43 2020
ISSN: ISSN 0002-7863 PubMed: 20415477 DOI: 10.1021/JA101557K |
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