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Atomistry » Bromine » PDB 2xpn-3bnq » 2ze1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Bromine » PDB 2xpn-3bnq » 2ze1 » |
Bromine in PDB 2ze1: X-Ray Structure of Bace-1 in Complex with Compound 6GEnzymatic activity of X-Ray Structure of Bace-1 in Complex with Compound 6G
All present enzymatic activity of X-Ray Structure of Bace-1 in Complex with Compound 6G:
3.4.23.46; Protein crystallography data
The structure of X-Ray Structure of Bace-1 in Complex with Compound 6G, PDB code: 2ze1
was solved by
R.Chopra,
A.Olland,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the X-Ray Structure of Bace-1 in Complex with Compound 6G
(pdb code 2ze1). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the X-Ray Structure of Bace-1 in Complex with Compound 6G, PDB code: 2ze1: Bromine binding site 1 out of 1 in 2ze1Go back to![]() ![]()
Bromine binding site 1 out
of 1 in the X-Ray Structure of Bace-1 in Complex with Compound 6G
![]() Mono view ![]() Stereo pair view
Reference:
D.C.Cole,
J.R.Stock,
R.Chopra,
R.Cowling,
J.W.Ellingboe,
K.Y.Fan,
B.L.Harrison,
Y.Hu,
S.Jacobsen,
L.D.Jennings,
G.Jin,
P.A.Lohse,
M.S.Malamas,
E.S.Manas,
W.J.Moore,
M.M.O'donnell,
A.M.Olland,
A.J.Robichaud,
K.Svenson,
J.Wu,
E.Wagner,
J.Bard.
Acylguanidine Inhibitors of Beta-Secretase: Optimization of the Pyrrole Ring Substituents Extending Into the S1 and S3 Substrate Binding Pockets. Bioorg.Med.Chem.Lett. V. 18 1063 2008.
Page generated: Mon Jul 7 04:59:34 2025
ISSN: ISSN 0960-894X PubMed: 18162398 DOI: 10.1016/J.BMCL.2007.12.010 |
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