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Atomistry » Bromine » PDB 2xpn-3bnq » 2zjl » |
Bromine in PDB 2zjl: Crystal Structure of the Human BACE1 Catalytic Domain in Complex with N-[1-(5-Bromo-2,3-Dimethoxy-Benzyl)-Piperidin- 4-Yl]-4-Mercapto-ButyramideEnzymatic activity of Crystal Structure of the Human BACE1 Catalytic Domain in Complex with N-[1-(5-Bromo-2,3-Dimethoxy-Benzyl)-Piperidin- 4-Yl]-4-Mercapto-Butyramide
All present enzymatic activity of Crystal Structure of the Human BACE1 Catalytic Domain in Complex with N-[1-(5-Bromo-2,3-Dimethoxy-Benzyl)-Piperidin- 4-Yl]-4-Mercapto-Butyramide:
3.4.23.46; Protein crystallography data
The structure of Crystal Structure of the Human BACE1 Catalytic Domain in Complex with N-[1-(5-Bromo-2,3-Dimethoxy-Benzyl)-Piperidin- 4-Yl]-4-Mercapto-Butyramide, PDB code: 2zjl
was solved by
M.Randal,
M.B.Lam,
W.Lu,
M.J.Romanowski,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of the Human BACE1 Catalytic Domain in Complex with N-[1-(5-Bromo-2,3-Dimethoxy-Benzyl)-Piperidin- 4-Yl]-4-Mercapto-Butyramide
(pdb code 2zjl). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of the Human BACE1 Catalytic Domain in Complex with N-[1-(5-Bromo-2,3-Dimethoxy-Benzyl)-Piperidin- 4-Yl]-4-Mercapto-Butyramide, PDB code: 2zjl: Bromine binding site 1 out of 1 in 2zjlGo back to![]() ![]()
Bromine binding site 1 out
of 1 in the Crystal Structure of the Human BACE1 Catalytic Domain in Complex with N-[1-(5-Bromo-2,3-Dimethoxy-Benzyl)-Piperidin- 4-Yl]-4-Mercapto-Butyramide
![]() Mono view ![]() Stereo pair view
Reference:
W.Yang,
R.V.Fucini,
B.T.Fahr,
M.Randal,
K.E.Lind,
M.B.Lam,
W.Lu,
Y.Lu,
D.R.Cary,
M.J.Romanowski.
Fragment-Based Discovery of Novel BACE1 Inhibitors Using Tethering Technology To Be Published.
Page generated: Mon Jul 7 04:59:50 2025
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