Atomistry » Bromine » PDB 3bnr-3e01 » 3c51
Atomistry »
  Bromine »
    PDB 3bnr-3e01 »
      3c51 »

Bromine in PDB 3c51: Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A

Enzymatic activity of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A

All present enzymatic activity of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A:
2.7.11.14;

Protein crystallography data

The structure of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A, PDB code: 3c51 was solved by P.Singh, J.J.G.Tesmer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.88 / 3.55
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 58.657, 92.527, 259.383, 90.00, 90.00, 90.00
R / Rfree (%) 28.1 / n/a

Other elements in 3c51:

The structure of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A also contains other interesting chemical elements:

Magnesium (Mg) 4 atoms

Bromine Binding Sites:

The binding sites of Bromine atom in the Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A (pdb code 3c51). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 5 binding sites of Bromine where determined in the Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A, PDB code: 3c51:
Jump to Bromine binding site number: 1; 2; 3; 4; 5;

Bromine binding site 1 out of 5 in 3c51

Go back to Bromine Binding Sites List in 3c51
Bromine binding site 1 out of 5 in the Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Br565

b:0.9
occ:1.00
 NH2 B:ARG170 3.5 0.1 1.0
N A:LEU166 3.7 0.7 1.0
CG A:LEU166 3.8 0.8 1.0
NE2 B:GLN173 3.8 0.4 1.0
CD1 A:LEU166 3.9 0.2 1.0
CB A:LEU166 4.1 0.1 1.0
CB A:SER165 4.1 0.3 1.0
OE1 B:GLN173 4.2 0.8 1.0
CD B:GLN173 4.3 0.1 1.0
CA A:SER165 4.4 0.8 1.0
CE1 A:HIS79 4.5 0.2 1.0
NE2 A:HIS79 4.5 0.7 1.0
CA A:LEU166 4.6 0.2 1.0
C A:SER165 4.6 0.3 1.0
CE1 A:TYR167 4.6 0.0 1.0
CZ B:ARG170 4.7 0.1 1.0
CD1 A:TYR167 4.8 0.3 1.0
NE B:ARG170 5.0 1.0 1.0

Bromine binding site 2 out of 5 in 3c51

Go back to Bromine Binding Sites List in 3c51
Bromine binding site 2 out of 5 in the Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br566

b:0.7
occ:1.00
 N A:PHE389 2.9 0.9 1.0
N A:ARG390 3.1 0.9 1.0
N A:PRO388 3.3 0.9 1.0
CD A:PRO388 3.3 0.0 1.0
C A:GLY387 3.5 0.8 1.0
CG A:ARG390 3.5 0.5 1.0
CD A:ARG390 3.5 0.4 1.0
CA A:PHE389 3.6 0.3 1.0
CG A:PRO388 3.6 0.5 1.0
CB A:PHE389 3.6 0.4 1.0
C A:PRO388 3.7 0.6 1.0
CD1 A:PHE389 3.7 0.1 1.0
CA A:GLY387 3.7 0.7 1.0
CB A:ARG390 3.8 0.5 1.0
C A:PHE389 3.8 0.5 1.0
NE A:ARG390 3.9 0.8 1.0
CA A:PRO388 3.9 0.3 1.0
CG A:PHE389 4.0 0.5 1.0
CA A:ARG390 4.1 0.1 1.0
O A:GLY387 4.2 0.1 1.0
CB A:PRO388 4.3 0.2 1.0
CZ A:ARG390 4.3 0.4 1.0
O A:GLY354 4.4 0.2 1.0
NH1 A:ARG390 4.4 0.7 1.0
O A:PRO388 4.6 0.7 1.0
CE1 A:PHE389 4.7 0.1 1.0
O A:ARG390 4.8 0.1 1.0
CG1 A:VAL377 4.9 0.3 1.0
C A:ARG390 5.0 0.2 1.0

Bromine binding site 3 out of 5 in 3c51

Go back to Bromine Binding Sites List in 3c51
Bromine binding site 3 out of 5 in the Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 3 of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Br566

b:99.9
occ:1.00
 N B:LEU166 3.6 0.8 1.0
NE2 A:GLN173 3.6 0.8 1.0
NH2 A:ARG170 3.8 0.9 1.0
CD1 B:LEU166 3.8 0.9 1.0
CG B:LEU166 3.8 0.2 1.0
OE1 A:GLN173 4.0 0.9 1.0
CB B:LEU166 4.0 0.0 1.0
CB B:SER165 4.0 0.3 1.0
CE1 B:TYR167 4.1 0.6 1.0
CA B:SER165 4.2 0.7 1.0
CD A:GLN173 4.3 0.7 1.0
CD1 B:TYR167 4.3 0.5 1.0
CA B:LEU166 4.4 0.3 1.0
C B:SER165 4.5 0.2 1.0
OG B:SER165 4.5 0.0 1.0
CE1 B:HIS79 4.6 0.6 1.0
CZ A:ARG170 4.8 0.3 1.0
NE A:ARG170 4.9 0.8 1.0

Bromine binding site 4 out of 5 in 3c51

Go back to Bromine Binding Sites List in 3c51
Bromine binding site 4 out of 5 in the Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 4 of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br567

b:0.8
occ:1.00
 CD1 A:LEU212 3.7 0.4 1.0
CZ A:PHE190 3.8 0.3 1.0
CE1 A:PHE190 3.8 0.6 1.0
NH2 A:ARG191 4.0 0.2 1.0
ND2 A:ASN268 4.6 0.4 1.0
CZ A:ARG191 4.9 0.0 1.0
CG A:LEU212 4.9 0.8 1.0
NE A:ARG191 5.0 0.7 1.0

Bromine binding site 5 out of 5 in 3c51

Go back to Bromine Binding Sites List in 3c51
Bromine binding site 5 out of 5 in the Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 5 of Crystal Structure of G Protein Coupled Receptor Kinase 1 Bound to Adp and Magnesium Chloride at 3.55A within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br568

b:0.6
occ:1.00
 CG A:ARG532 3.5 0.4 1.0
N A:ARG532 3.8 1.0 1.0
N B:ARG532 3.8 0.1 1.0
CB B:TRP531 3.9 0.1 1.0
CG B:ARG532 4.0 0.4 1.0
O A:ARG532 4.0 0.8 1.0
CB A:TRP531 4.0 0.6 1.0
O B:ARG532 4.1 0.7 1.0
N B:TRP531 4.3 0.5 1.0
CD A:ARG532 4.5 1.0 1.0
CA B:TRP531 4.5 0.5 1.0
CA A:ARG532 4.5 0.5 1.0
N A:TRP531 4.6 0.7 1.0
C A:ARG532 4.6 0.6 1.0
CB A:ARG532 4.6 0.2 1.0
CA B:ARG532 4.6 0.4 1.0
C B:ARG532 4.7 0.5 1.0
CA A:TRP531 4.7 0.6 1.0
C B:TRP531 4.7 0.4 1.0
C A:TRP531 4.8 0.5 1.0
CD1 B:TRP531 4.8 0.4 1.0
CG B:TRP531 4.8 0.8 1.0
CB B:ARG532 4.9 0.1 1.0
CG A:TRP531 4.9 0.6 1.0
CD1 A:TRP531 4.9 0.9 1.0

Reference:

P.Singh, B.Wang, T.Maeda, K.Palczewski, J.J.Tesmer. Structures of Rhodopsin Kinase in Different Ligand States Reveal Key Elements Involved in G Protein-Coupled Receptor Kinase Activation. J.Biol.Chem. V. 283 14053 2008.
ISSN: ISSN 0021-9258
PubMed: 18339619
DOI: 10.1074/JBC.M708974200
Page generated: Wed Jul 10 19:11:50 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy