Bromine in PDB 3frc: Tetramerization and Cooperativity in Plasmodium Falciparum Glutathione Transferase Are Mediated By the Atypic Loop 113-118

All present enzymatic activity of Tetramerization and Cooperativity in Plasmodium Falciparum Glutathione Transferase Are Mediated By the Atypic Loop 113-118:
2.5.1.18;

The structure of Tetramerization and Cooperativity in Plasmodium Falciparum Glutathione Transferase Are Mediated By the Atypic Loop 113-118, PDB code: 3frc was solved by M.Perbandt, E.Liebau, G.Ricci, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.71 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	57.472, 69.407, 123.323, 90.00, 90.00, 90.00
R / Rfree (%)	22 / 26.8

The binding sites of Bromine atom in the Tetramerization and Cooperativity in Plasmodium Falciparum Glutathione Transferase Are Mediated By the Atypic Loop 113-118 (pdb code 3frc). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Tetramerization and Cooperativity in Plasmodium Falciparum Glutathione Transferase Are Mediated By the Atypic Loop 113-118, PDB code: 3frc:
Jump to Bromine binding site number: 1; 2;

Bromine binding site 1 out of 2 in the Tetramerization and Cooperativity in Plasmodium Falciparum Glutathione Transferase Are Mediated By the Atypic Loop 113-118


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Tetramerization and Cooperativity in Plasmodium Falciparum Glutathione Transferase Are Mediated By the Atypic Loop 113-118 within 5.0Å range: probe atom residue distance (Å) B Occ A:Br212 b:28.8 occ:0.80 BR A:0HG212 0.0 28.8 0.8 C4 A:0HG212 1.9 28.2 0.8 C5 A:0HG212 2.8 27.9 0.8 C3 A:0HG212 2.9 27.9 0.8 ND2 A:ASN111 3.3 27.7 1.0 O A:HOH315 3.5 22.5 1.0 CG A:ASN111 3.6 27.1 1.0 CD1 A:LEU115 3.8 36.9 1.0 OD1 A:ASN111 3.9 27.1 1.0 CG A:LYS15 4.1 24.0 1.0 CA A:GLY14 4.1 24.9 1.0 C6 A:0HG212 4.1 27.8 0.8 C2 A:0HG212 4.2 28.1 0.8 CB A:ASN111 4.2 27.2 1.0 C A:GLY14 4.3 24.5 1.0 O A:HOH264 4.4 34.5 1.0 N A:LYS15 4.4 23.6 1.0 NZ A:LYS15 4.5 27.9 1.0 CE A:LYS15 4.6 26.0 1.0 C11 A:0HG212 4.7 28.0 0.8 O A:HOH314 4.7 29.1 1.0 OH A:TYR9 4.8 22.0 1.0 O A:GLY14 4.9 24.8 1.0 CD A:LYS15 4.9 25.3 1.0 CZ A:PHE116 5.0 39.3 1.0

Bromine binding site 2 out of 2 in the Tetramerization and Cooperativity in Plasmodium Falciparum Glutathione Transferase Are Mediated By the Atypic Loop 113-118


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Tetramerization and Cooperativity in Plasmodium Falciparum Glutathione Transferase Are Mediated By the Atypic Loop 113-118 within 5.0Å range: probe atom residue distance (Å) B Occ B:Br212 b:34.0 occ:0.80 BR B:0HG212 0.0 34.0 0.8 C4 B:0HG212 1.9 32.8 0.8 C5 B:0HG212 2.8 32.6 0.8 C3 B:0HG212 2.8 33.1 0.8 ND2 B:ASN111 3.4 27.1 1.0 CG B:ASN111 3.5 27.8 1.0 CD1 B:LEU115 3.6 42.8 1.0 OD1 B:ASN111 3.7 27.1 1.0 O B:HOH341 4.1 32.8 1.0 CG B:LYS15 4.1 21.5 1.0 C6 B:0HG212 4.1 32.6 0.8 C2 B:0HG212 4.1 32.7 0.8 CA B:GLY14 4.1 21.3 1.0 CB B:ASN111 4.3 28.2 1.0 N B:LYS15 4.3 20.6 1.0 C B:TYR211 4.4 48.9 1.0 NZ B:LYS15 4.4 28.1 1.0 C B:GLY14 4.4 20.8 1.0 CD B:LYS15 4.5 25.0 1.0 OH B:TYR9 4.6 18.3 1.0 O B:HOH297 4.6 42.1 1.0 C11 B:0HG212 4.6 32.1 0.8 O B:TYR211 4.8 49.0 1.0 CG B:LEU115 5.0 41.9 1.0

M.Perbandt, E.Liebau, G.Ricci. Tetramerization and Cooperativity in Plasmodium Falciparum Glutathione Transferase Are Mediated By the Atypic Loop 113-118 To Be Published.