Atomistry » Bromine » PDB 3gw6-3jtk » 3h4b
Atomistry »
  Bromine »
    PDB 3gw6-3jtk »
      3h4b »

Bromine in PDB 3h4b: Ternary Complex of Human Dna Polymerase Iota with Template U/T and Incoming Datp

Enzymatic activity of Ternary Complex of Human Dna Polymerase Iota with Template U/T and Incoming Datp

All present enzymatic activity of Ternary Complex of Human Dna Polymerase Iota with Template U/T and Incoming Datp:
2.7.7.7;

Protein crystallography data

The structure of Ternary Complex of Human Dna Polymerase Iota with Template U/T and Incoming Datp, PDB code: 3h4b was solved by R.Jain, D.T.Nair, R.E.Johnson, L.Prakash, S.Prakash, A.K.Aggarwal, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 39.73 / 2.85
Space group P 65 2 2
Cell size a, b, c (Å), α, β, γ (°) 97.998, 97.998, 203.670, 90.00, 90.00, 120.00
R / Rfree (%) 24 / 28.1

Other elements in 3h4b:

The structure of Ternary Complex of Human Dna Polymerase Iota with Template U/T and Incoming Datp also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Bromine Binding Sites:

The binding sites of Bromine atom in the Ternary Complex of Human Dna Polymerase Iota with Template U/T and Incoming Datp (pdb code 3h4b). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Ternary Complex of Human Dna Polymerase Iota with Template U/T and Incoming Datp, PDB code: 3h4b:
Jump to Bromine binding site number: 1; 2;

Bromine binding site 1 out of 2 in 3h4b

Go back to Bromine Binding Sites List in 3h4b
Bromine binding site 1 out of 2 in the Ternary Complex of Human Dna Polymerase Iota with Template U/T and Incoming Datp


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Ternary Complex of Human Dna Polymerase Iota with Template U/T and Incoming Datp within 5.0Å range:
probe atom residue distance (Å) B Occ
T:Br840

b:0.8
occ:0.90
BR T:BRU840 0.0 0.8 0.9
C5 T:BRU840 1.9 43.8 0.9
C6 T:BRU840 2.8 45.9 0.9
C4 T:BRU840 2.9 43.3 0.9
O4 T:BRU840 3.1 43.2 0.9
C2' T:DT839 3.3 74.5 1.0
O2 T:BRU840 3.4 55.0 0.1
C3' T:DT839 3.7 72.1 1.0
O T:HOH170 3.8 32.6 1.0
C6 T:DT839 4.0 78.5 1.0
N1 T:BRU840 4.1 45.7 0.9
N3 T:BRU840 4.1 42.9 0.9
C2 T:BRU840 4.2 54.9 0.1
N3 T:BRU840 4.2 55.0 0.1
O T:HOH169 4.3 54.9 1.0
O5' T:DT839 4.4 75.5 1.0
C1' T:DT839 4.6 76.4 1.0
C7 T:DT839 4.6 79.7 1.0
O3' T:DT839 4.6 67.0 1.0
C2 T:BRU840 4.7 44.3 0.9
C5 T:DT839 4.7 79.1 1.0
N1 T:DT839 4.7 77.8 1.0
C4' T:DT839 4.8 74.4 1.0
C5' T:DT839 4.8 75.0 1.0
N7 T:DG841 4.8 28.4 1.0

Bromine binding site 2 out of 2 in 3h4b

Go back to Bromine Binding Sites List in 3h4b
Bromine binding site 2 out of 2 in the Ternary Complex of Human Dna Polymerase Iota with Template U/T and Incoming Datp


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Ternary Complex of Human Dna Polymerase Iota with Template U/T and Incoming Datp within 5.0Å range:
probe atom residue distance (Å) B Occ
T:Br840

b:72.1
occ:0.10
BR T:BRU840 0.0 72.1 0.1
N6 A:DTP875 1.8 62.4 0.9
C5 T:BRU840 1.9 55.1 0.1
C6 T:BRU840 2.8 55.0 0.1
O2 T:BRU840 2.9 44.7 0.9
C4 T:BRU840 2.9 55.0 0.1
C6 A:DTP875 3.1 63.4 0.9
O A:HOH530 3.1 58.6 1.0
O4 T:BRU840 3.2 54.9 0.1
C2 T:DG841 3.3 27.4 1.0
N2 T:DG841 3.4 25.8 1.0
N1 T:DG841 3.5 26.9 1.0
N3 T:DG841 3.7 28.8 1.0
N1 A:DTP875 3.7 63.3 0.9
C2 T:BRU840 3.8 44.3 0.9
N1 T:BRU840 4.1 54.9 0.1
N3 T:BRU840 4.1 55.0 0.1
OE1 A:GLN59 4.2 48.5 1.0
N3 T:BRU840 4.2 42.9 0.9
C6 T:DG841 4.2 28.4 1.0
C5 A:DTP875 4.2 64.8 0.9
C4 T:DG841 4.2 29.4 1.0
C5 T:DG841 4.5 27.5 1.0
CG1 A:VAL64 4.5 36.2 1.0
N7 A:DTP875 4.7 65.7 0.9
O2 P:DOC873 4.7 35.6 1.0
CB A:VAL64 4.7 37.8 1.0
C2 T:BRU840 4.7 54.9 0.1
O6 T:DG841 4.9 30.1 1.0
N3 P:DOC873 4.9 36.8 1.0

Reference:

R.Jain, D.T.Nair, R.E.Johnson, L.Prakash, S.Prakash, A.K.Aggarwal. Replication Across Template T/U By Human Dna Polymerase-Iota. Structure V. 17 974 2009.
ISSN: ISSN 0969-2126
PubMed: 19604477
DOI: 10.1016/J.STR.2009.04.011
Page generated: Sat Dec 12 02:12:15 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy