Bromine in PDB 3hov: Complete Rna Polymerase II Elongation Complex II

All present enzymatic activity of Complete Rna Polymerase II Elongation Complex II:
2.7.7.6;

The structure of Complete Rna Polymerase II Elongation Complex II, PDB code: 3hov was solved by J.F.Sydow, F.Brueckner, A.C.M.Cheung, G.E.Damsma, S.Dengl, E.Lehmann, D.Vassylyev, P.Cramer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 3.50
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	222.252, 393.383, 283.091, 90.00, 90.00, 90.00
R / Rfree (%)	21 / 22.6

The structure of Complete Rna Polymerase II Elongation Complex II also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Zinc	(Zn)	8 atoms

The binding sites of Bromine atom in the Complete Rna Polymerase II Elongation Complex II (pdb code 3hov). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Complete Rna Polymerase II Elongation Complex II, PDB code: 3hov:

Bromine binding site 1 out of 1 in the Complete Rna Polymerase II Elongation Complex II


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Complete Rna Polymerase II Elongation Complex II within 5.0Å range: probe atom residue distance (Å) B Occ T:Br23 b:0.8 occ:1.00 BR T:BRU23 0.0 0.8 1.0 C5 T:BRU23 1.5 0.0 1.0 C6 T:BRU23 2.5 0.3 1.0 C4 T:BRU23 2.5 0.5 1.0 O4 T:BRU23 2.9 0.2 1.0 C2 T:DC22 3.6 0.2 1.0 N3 T:DC22 3.6 0.5 1.0 N1 T:DC22 3.6 0.8 1.0 C4 T:DC22 3.7 0.4 1.0 C6 T:DC22 3.8 0.7 1.0 C5 T:DC22 3.8 0.8 1.0 N3 T:BRU23 3.8 0.2 1.0 N1 T:BRU23 3.8 0.9 1.0 C2' T:DC22 3.8 0.2 1.0 O2 T:DC22 4.2 0.2 1.0 C1' T:DC22 4.3 0.7 1.0 N4 T:DC22 4.3 0.6 1.0 C2 T:BRU23 4.3 0.9 1.0 OP2 T:BRU23 4.7 0.9 1.0 C1' T:BRU23 5.0 0.7 1.0

J.F.Sydow, F.Brueckner, A.C.M.Cheung, G.E.Damsma, S.Dengl, E.Lehmann, D.Vassylyev, P.Cramer. Structural Basis of Transcription: Mismatch-Specific Fidelity Mechanisms and Paused Rna Polymerase II with Frayed Rna. Mol.Cell V. 34 710 2009.
ISSN: ISSN 1097-2765
PubMed: 19560423
DOI: 10.1016/J.MOLCEL.2009.06.002