Bromine in PDB 3hox: Complete Rna Polymerase II Elongation Complex V

All present enzymatic activity of Complete Rna Polymerase II Elongation Complex V:
2.7.7.6;

The structure of Complete Rna Polymerase II Elongation Complex V, PDB code: 3hox was solved by J.F.Sydow, F.Brueckner, A.C.M.Cheung, G.E.Damsma, S.Dengl, E.Lehmann, D.Vassylyev, P.Cramer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 3.65
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	221.617, 393.716, 282.576, 90.00, 90.00, 90.00
R / Rfree (%)	21.2 / 25

The structure of Complete Rna Polymerase II Elongation Complex V also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Zinc	(Zn)	8 atoms

The binding sites of Bromine atom in the Complete Rna Polymerase II Elongation Complex V (pdb code 3hox). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Complete Rna Polymerase II Elongation Complex V, PDB code: 3hox:

Bromine binding site 1 out of 1 in the Complete Rna Polymerase II Elongation Complex V


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Complete Rna Polymerase II Elongation Complex V within 5.0Å range: probe atom residue distance (Å) B Occ T:Br23 b:0.4 occ:1.00 BR T:BRU23 0.0 0.4 1.0 C5 T:BRU23 1.5 0.9 1.0 C6 T:BRU23 2.5 0.8 1.0 C4 T:BRU23 2.6 0.6 1.0 O4 T:BRU23 2.9 0.6 1.0 N1 T:DC22 3.4 0.3 1.0 C2' T:DC22 3.5 0.5 1.0 C6 T:DC22 3.6 0.1 1.0 C2 T:DC22 3.6 0.5 1.0 C5 T:DC22 3.7 0.2 1.0 N3 T:DC22 3.8 0.2 1.0 N3 T:BRU23 3.8 1.0 1.0 N1 T:BRU23 3.8 0.2 1.0 C4 T:DC22 3.8 0.6 1.0 C1' T:DC22 4.0 0.1 1.0 OP2 T:BRU23 4.0 0.9 1.0 O2 T:DC22 4.2 0.3 1.0 C2 T:BRU23 4.4 0.4 1.0 N4 T:DC22 4.6 0.1 1.0 C3' T:DC22 4.9 0.8 1.0 O4' T:BRU23 5.0 0.4 1.0

J.F.Sydow, F.Brueckner, A.C.M.Cheung, G.E.Damsma, S.Dengl, E.Lehmann, D.Vassylyev, P.Cramer. Structural Basis of Transcription: Mismatch-Specific Fidelity Mechanisms and Paused Rna Polymerase II with Frayed Rna. Mol.Cell V. 34 710 2009.
ISSN: ISSN 1097-2765
PubMed: 19560423
DOI: 10.1016/J.MOLCEL.2009.06.002