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Bromine in PDB 3hoz: Complete Rna Polymerase II Elongation Complex IV with A T-U Mismatch and A Frayed Rna 3'-Guanine

Enzymatic activity of Complete Rna Polymerase II Elongation Complex IV with A T-U Mismatch and A Frayed Rna 3'-Guanine

All present enzymatic activity of Complete Rna Polymerase II Elongation Complex IV with A T-U Mismatch and A Frayed Rna 3'-Guanine:
2.7.7.6;

Protein crystallography data

The structure of Complete Rna Polymerase II Elongation Complex IV with A T-U Mismatch and A Frayed Rna 3'-Guanine, PDB code: 3hoz was solved by J.F.Sydow, F.Brueckner, A.C.M.Cheung, G.E.Damsma, S.Dengl, E.Lehmann, D.Vassylyev, P.Cramer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 3.65
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 221.427, 393.750, 281.818, 90.00, 90.00, 90.00
R / Rfree (%) 21 / 25.3

Other elements in 3hoz:

The structure of Complete Rna Polymerase II Elongation Complex IV with A T-U Mismatch and A Frayed Rna 3'-Guanine also contains other interesting chemical elements:

Magnesium (Mg) 1 atom
Zinc (Zn) 8 atoms

Bromine Binding Sites:

The binding sites of Bromine atom in the Complete Rna Polymerase II Elongation Complex IV with A T-U Mismatch and A Frayed Rna 3'-Guanine (pdb code 3hoz). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Complete Rna Polymerase II Elongation Complex IV with A T-U Mismatch and A Frayed Rna 3'-Guanine, PDB code: 3hoz:

Bromine binding site 1 out of 1 in 3hoz

Go back to Bromine Binding Sites List in 3hoz
Bromine binding site 1 out of 1 in the Complete Rna Polymerase II Elongation Complex IV with A T-U Mismatch and A Frayed Rna 3'-Guanine


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Complete Rna Polymerase II Elongation Complex IV with A T-U Mismatch and A Frayed Rna 3'-Guanine within 5.0Å range:
probe atom residue distance (Å) B Occ
T:Br23

b:0.9
occ:1.00
BR T:BRU23 0.0 0.9 1.0
C5 T:BRU23 1.5 0.5 1.0
C6 T:BRU23 2.5 0.1 1.0
C4 T:BRU23 2.5 0.5 1.0
O4 T:BRU23 2.9 0.5 1.0
N1 T:DC22 3.4 0.1 1.0
C6 T:DC22 3.4 0.7 1.0
C2' T:DC22 3.5 0.9 1.0
C2 T:DC22 3.6 0.5 1.0
C5 T:DC22 3.7 0.4 1.0
N3 T:BRU23 3.8 0.4 1.0
N1 T:BRU23 3.8 0.6 1.0
N3 T:DC22 3.8 0.5 1.0
C4 T:DC22 3.8 0.0 1.0
C1' T:DC22 3.9 0.1 1.0
OP2 T:BRU23 4.2 0.7 1.0
O2 T:DC22 4.2 0.6 1.0
C2 T:BRU23 4.3 0.5 1.0
N4 T:DC22 4.6 0.3 1.0
C3' T:DC22 4.9 0.6 1.0
O4' T:BRU23 5.0 0.5 1.0
C1' T:BRU23 5.0 0.2 1.0

Reference:

J.F.Sydow, F.Brueckner, A.C.M.Cheung, G.E.Damsma, S.Dengl, E.Lehmann, D.Vassylyev, P.Cramer. Structural Basis of Transcription: Mismatch-Specific Fidelity Mechanisms and Paused Rna Polymerase II with Frayed Rna. Mol.Cell V. 34 710 2009.
ISSN: ISSN 1097-2765
PubMed: 19560423
DOI: 10.1016/J.MOLCEL.2009.06.002
Page generated: Wed Jul 10 19:40:48 2024

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