Bromine in PDB 3tq6: Crystal Structure of Human Mitochondrial Transcription Factor A, Tfam or Mttfa, Bound to the Light Strand Promoter Lsp

The structure of Crystal Structure of Human Mitochondrial Transcription Factor A, Tfam or Mttfa, Bound to the Light Strand Promoter Lsp, PDB code: 3tq6 was solved by A.Rubio-Cosials, J.F.Sydow, N.Jimenez-Menendez, P.Fernandez-Millan, J.Montoya, H.T.Jacobs, M.Coll, P.Bernado, M.Sola, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.84 / 2.45
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	113.900, 117.200, 56.530, 90.00, 90.00, 90.00
R / Rfree (%)	18.2 / 22.8

The binding sites of Bromine atom in the Crystal Structure of Human Mitochondrial Transcription Factor A, Tfam or Mttfa, Bound to the Light Strand Promoter Lsp (pdb code 3tq6). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Crystal Structure of Human Mitochondrial Transcription Factor A, Tfam or Mttfa, Bound to the Light Strand Promoter Lsp, PDB code: 3tq6:
Jump to Bromine binding site number: 1; 2;

Bromine binding site 1 out of 2 in the Crystal Structure of Human Mitochondrial Transcription Factor A, Tfam or Mttfa, Bound to the Light Strand Promoter Lsp


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of Human Mitochondrial Transcription Factor A, Tfam or Mttfa, Bound to the Light Strand Promoter Lsp within 5.0Å range: probe atom residue distance (Å) B Occ C:Br19 b:28.0 occ:0.35 BR C:BRU19 0.0 28.0 0.3 C5 C:BRU19 1.9 27.1 1.0 C6 C:BRU19 2.9 26.0 1.0 C4 C:BRU19 3.0 28.1 1.0 O4 C:BRU19 3.2 32.7 1.0 C6 C:DC18 3.7 30.1 1.0 O C:HOH531 3.9 36.5 1.0 C5 C:DC18 3.9 29.7 1.0 O C:HOH534 4.1 29.0 1.0 N1 C:BRU19 4.2 29.6 1.0 C2' C:DC18 4.2 29.7 1.0 N3 C:BRU19 4.2 26.7 1.0 N1 C:DC18 4.3 29.0 1.0 C2 C:BRU19 4.7 29.3 1.0 C1' C:DC18 4.8 29.8 1.0 C4 C:DC18 4.8 28.8 1.0

Bromine binding site 2 out of 2 in the Crystal Structure of Human Mitochondrial Transcription Factor A, Tfam or Mttfa, Bound to the Light Strand Promoter Lsp


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Crystal Structure of Human Mitochondrial Transcription Factor A, Tfam or Mttfa, Bound to the Light Strand Promoter Lsp within 5.0Å range: probe atom residue distance (Å) B Occ E:Br19 b:35.8 occ:0.37 BR E:BRU19 0.0 35.8 0.4 C5 E:BRU19 1.9 35.3 1.0 C6 E:BRU19 2.9 34.2 1.0 C4 E:BRU19 2.9 35.3 1.0 O E:HOH636 3.0 39.1 1.0 O4 E:BRU19 3.1 34.9 1.0 C6 E:DC18 3.8 31.4 1.0 C2' E:DC18 4.0 35.4 1.0 O E:HOH610 4.1 39.7 1.0 O E:HOH582 4.1 40.6 1.0 C5 E:DC18 4.2 31.7 1.0 N1 E:BRU19 4.2 34.2 1.0 N3 E:BRU19 4.2 36.2 1.0 N1 E:DC18 4.3 32.7 1.0 C1' E:DC18 4.7 34.8 1.0 C2 E:BRU19 4.7 34.8 1.0 C4 E:DC18 4.9 33.0 1.0 C2 E:DC18 5.0 31.1 1.0

A.Rubio-Cosials, J.F.Sidow, N.Jimenez-Menendez, P.Fernandez-Millan, J.Montoya, H.T.Jacobs, M.Coll, P.Bernado, M.Sola. Human Mitochondrial Transcription Factor A Induces A U-Turn Structure in the Light Strand Promoter. Nat.Struct.Mol.Biol. V. 18 1281 2011.
ISSN: ISSN 1545-9993
PubMed: 22037172
DOI: 10.1038/NSMB.2160