Bromine »
PDB 3u2d-3wk9 »
3u8i »
Bromine in PDB 3u8i: Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism
Enzymatic activity of Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism
All present enzymatic activity of Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism:
3.1.1.4;
3.1.1.4;
Protein crystallography data
The structure of Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism, PDB code: 3u8i
was solved by
L.K.Lee,
K.J.Bryant,
R.Bouveret,
P.-W.Lei,
A.P.Duff,
S.J.Harrop,
E.P.Huang,
R.P.Harvey,
M.H.Gelb,
P.P.Gray,
P.M.Curmi,
A.M.Cunningham,
W.B.Church,
K.F.Scott,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 34.31 / 1.10 |
| Space group | P 41 |
| Cell size a, b, c (Å), α, β, γ (°) | 70.426, 70.426, 47.301, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 16.4 / 18.6 |
Other elements in 3u8i:
The structure of Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism also contains other interesting chemical elements:
| Calcium | (Ca) | 4 atoms |
| Chlorine | (Cl) | 4 atoms |
| Sodium | (Na) | 4 atoms |
Bromine Binding Sites:
The binding sites of Bromine atom in the Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism
(pdb code 3u8i). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism, PDB code: 3u8i:
Jump to Bromine binding site number: 1; 2;
In total 2 binding sites of Bromine where determined in the Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism, PDB code: 3u8i:
Jump to Bromine binding site number: 1; 2;
Bromine binding site 1 out of 2 in 3u8i
Go back to
Bromine Binding Sites List in 3u8i
Bromine binding site 1 out
of 2 in the Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 1 of Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism within 5.0Å range:
|
Bromine binding site 2 out of 2 in 3u8i
Go back to
Bromine Binding Sites List in 3u8i
Bromine binding site 2 out
of 2 in the Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 2 of Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism within 5.0Å range:
|
Reference:
L.K.Lee,
K.J.Bryant,
R.Bouveret,
P.W.Lei,
A.P.Duff,
S.J.Harrop,
E.P.Huang,
R.P.Harvey,
M.H.Gelb,
P.P.Gray,
P.M.Curmi,
A.M.Cunningham,
W.B.Church,
K.F.Scott.
Selective Inhibition of Human Group Iia-Secreted Phospholipase A2 (Hgiia) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of Hgiia to Vimentin in Rheumatoid Synoviocytes. J.Biol.Chem. V. 288 15269 2013.
ISSN: ISSN 0021-9258
PubMed: 23482564
DOI: 10.1074/JBC.M112.397893
Page generated: Sat Dec 12 02:16:02 2020
ISSN: ISSN 0021-9258
PubMed: 23482564
DOI: 10.1074/JBC.M112.397893
Last articles
Zn in 8WB0Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
