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Atomistry » Bromine » PDB 4alu-4d45 » 4anm | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Bromine » PDB 4alu-4d45 » 4anm » |
Bromine in PDB 4anm: Complex of CK2 with A CDC7 InhibitorEnzymatic activity of Complex of CK2 with A CDC7 Inhibitor
All present enzymatic activity of Complex of CK2 with A CDC7 Inhibitor:
2.7.11.1; Protein crystallography data
The structure of Complex of CK2 with A CDC7 Inhibitor, PDB code: 4anm
was solved by
T.J.Stout,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the Complex of CK2 with A CDC7 Inhibitor
(pdb code 4anm). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Complex of CK2 with A CDC7 Inhibitor, PDB code: 4anm: Bromine binding site 1 out of 1 in 4anmGo back to![]() ![]()
Bromine binding site 1 out
of 1 in the Complex of CK2 with A CDC7 Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
E.S.Koltun,
A.L.Tsuhako,
D.S.Brown,
N.Aay,
A.Arcalas,
V.Chan,
H.Du,
S.Engst,
K.Ferguson,
M.Franzini,
A.Galan,
C.R.Holst,
P.Huang,
B.Kane,
M.H.Kim,
J.Li,
D.Markby,
M.Mohan,
K.Noson,
A.Plonowski,
S.J.Richards,
S.Robertson,
K.Shaw,
G.Stott,
T.J.Stout,
J.Young,
P.Yu,
C.A.Zaharia,
W.Zhang,
P.Zhou,
J.M.Nuss,
W.Xu,
P.C.Kearney.
Discovery of XL413, A Potent and Selective CDC7 Inhibitor. Bioorg.Med.Chem.Lett. V. 22 3727 2012.
Page generated: Sat Dec 12 02:18:10 2020
ISSN: ISSN 0960-894X PubMed: 22560567 DOI: 10.1016/J.BMCL.2012.04.024 |
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