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Atomistry » Bromine » PDB 4alv-4d46 » 4bcw » |
Bromine in PDB 4bcw: Carbonic Anhydrase IX Mimic in Complex with (E)-2-(5-Bromo-2- Hydroxyphenyl)Ethenesulfonic AcidEnzymatic activity of Carbonic Anhydrase IX Mimic in Complex with (E)-2-(5-Bromo-2- Hydroxyphenyl)Ethenesulfonic Acid
All present enzymatic activity of Carbonic Anhydrase IX Mimic in Complex with (E)-2-(5-Bromo-2- Hydroxyphenyl)Ethenesulfonic Acid:
4.2.1.1; Protein crystallography data
The structure of Carbonic Anhydrase IX Mimic in Complex with (E)-2-(5-Bromo-2- Hydroxyphenyl)Ethenesulfonic Acid, PDB code: 4bcw
was solved by
K.Tars,
J.Leitans,
A.Kazaks,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4bcw:
The structure of Carbonic Anhydrase IX Mimic in Complex with (E)-2-(5-Bromo-2- Hydroxyphenyl)Ethenesulfonic Acid also contains other interesting chemical elements:
Bromine Binding Sites:
The binding sites of Bromine atom in the Carbonic Anhydrase IX Mimic in Complex with (E)-2-(5-Bromo-2- Hydroxyphenyl)Ethenesulfonic Acid
(pdb code 4bcw). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Carbonic Anhydrase IX Mimic in Complex with (E)-2-(5-Bromo-2- Hydroxyphenyl)Ethenesulfonic Acid, PDB code: 4bcw: Bromine binding site 1 out of 1 in 4bcwGo back to Bromine Binding Sites List in 4bcw
Bromine binding site 1 out
of 1 in the Carbonic Anhydrase IX Mimic in Complex with (E)-2-(5-Bromo-2- Hydroxyphenyl)Ethenesulfonic Acid
Mono view Stereo pair view
Reference:
K.Tars,
D.Vullo,
A.Kazaks,
J.Leitans,
A.Lends,
A.Grandane,
R.Zalubovskis,
A.Scozzafava,
C.T.Supuran.
Sulfocoumarins (1,2-Benzoxathiine-2,2-Dioxides): A Class of Potent and Isoform-Selective Inhibitors of Tumor-Associated Carbonic Anhydrases. J.Med.Chem. V. 56 293 2013.
Page generated: Sat Dec 12 02:18:18 2020
ISSN: ISSN 0022-2623 PubMed: 23241068 DOI: 10.1021/JM301625S |
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