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Atomistry » Bromine » PDB 4alv-4d46 » 4bgh » |
Bromine in PDB 4bgh: Crystal Structure of CDK2 in Complex with Pan-Cdk InhibitorEnzymatic activity of Crystal Structure of CDK2 in Complex with Pan-Cdk Inhibitor
All present enzymatic activity of Crystal Structure of CDK2 in Complex with Pan-Cdk Inhibitor:
2.7.11.22; Protein crystallography data
The structure of Crystal Structure of CDK2 in Complex with Pan-Cdk Inhibitor, PDB code: 4bgh
was solved by
U.Luecking,
R.Jautelat,
M.Krueger,
T.Brumby,
P.Lienau,
M.Schaefer,
H.Briem,
J.Schulze,
A.Hillisch,
A.Reichel,
G.Siemeister,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of CDK2 in Complex with Pan-Cdk Inhibitor
(pdb code 4bgh). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of CDK2 in Complex with Pan-Cdk Inhibitor, PDB code: 4bgh: Bromine binding site 1 out of 1 in 4bghGo back to Bromine Binding Sites List in 4bgh
Bromine binding site 1 out
of 1 in the Crystal Structure of CDK2 in Complex with Pan-Cdk Inhibitor
Mono view Stereo pair view
Reference:
U.Lucking,
R.Jautelat,
M.Kruger,
T.Brumby,
P.Lienau,
M.Schafer,
H.Briem,
J.Schulze,
A.Hillisch,
A.Reichel,
A.M.Wengner,
G.Siemeister.
The Lab Oddity Prevails: Discovery of Pan-Cdk Inhibitor (R)- S-Cyclopropyl-S-(4-{[4-{[(1R,2R)-2-Hydroxy-1- Methylpropyl]Oxy}-5-(Trifluoromethyl)Pyrimidin-2- Yl]Amino}Phenyl)Sulfoximide (Bay 1000394) For the Treatment of Cancer. Chemmedchem V. 8 1067 2013.
Page generated: Sat Dec 12 02:18:19 2020
ISSN: ISSN 1860-7179 PubMed: 23671017 DOI: 10.1002/CMDC.201300096 |
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