Bromine in PDB 4cv5: Yeast NOT1 CN9BD-CAF40 Complex

The structure of Yeast NOT1 CN9BD-CAF40 Complex, PDB code: 4cv5 was solved by J.Basquin, E.Conti, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.292 / 3.807
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	188.339, 188.339, 126.689, 90.00, 90.00, 90.00
R / Rfree (%)	27.64 / 29.52

The structure of Yeast NOT1 CN9BD-CAF40 Complex also contains other interesting chemical elements:

Tantalum

(Ta)

18 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 36;

Binding sites:

The binding sites of Bromine atom in the Yeast NOT1 CN9BD-CAF40 Complex (pdb code 4cv5). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 36 binding sites of Bromine where determined in the Yeast NOT1 CN9BD-CAF40 Complex, PDB code: 4cv5:
Jump to Bromine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Bromine binding site 1 out of 36 in the Yeast NOT1 CN9BD-CAF40 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Yeast NOT1 CN9BD-CAF40 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br2272 b:0.1 occ:0.29 BR1 A:TBR2272 0.0 0.1 0.3 TA2 A:TBR2272 2.6 0.5 0.3 TA1 A:TBR2272 2.6 0.1 0.3 BR2 A:TBR2272 3.6 0.5 0.3 BR5 A:TBR2272 3.6 0.4 0.3 BRC A:TBR2272 3.6 0.6 0.3 BR4 A:TBR2272 3.7 0.7 0.3 TA3 A:TBR2272 4.2 0.5 0.3 TA6 A:TBR2272 4.2 0.9 0.3 CD A:ARG1145 4.2 77.2 1.0 CB A:HIS1146 4.4 1.0 1.0 CG A:ARG1145 4.4 77.2 1.0 CA A:HIS1146 4.8 0.3 1.0 N A:HIS1146 5.0 0.1 1.0

Bromine binding site 2 out of 36 in the Yeast NOT1 CN9BD-CAF40 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Yeast NOT1 CN9BD-CAF40 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br2272 b:0.5 occ:0.29 BR2 A:TBR2272 0.0 0.5 0.3 TA1 A:TBR2272 2.6 0.1 0.3 TA3 A:TBR2272 2.6 0.5 0.3 ND1 A:HIS1146 2.9 0.3 1.0 BR1 A:TBR2272 3.6 0.1 0.3 CG A:HIS1146 3.6 0.5 1.0 BR3 A:TBR2272 3.6 0.9 0.3 BR6 A:TBR2272 3.6 0.7 0.3 BR5 A:TBR2272 3.6 0.4 0.3 CE1 A:HIS1146 3.7 0.3 1.0 CB A:HIS1146 3.9 1.0 1.0 TA2 A:TBR2272 4.2 0.5 0.3 TA5 A:TBR2272 4.2 0.1 0.3 CA A:HIS1146 4.3 0.3 1.0 CD2 A:HIS1146 4.5 0.2 1.0 NE2 A:HIS1146 4.5 0.9 1.0

Bromine binding site 3 out of 36 in the Yeast NOT1 CN9BD-CAF40 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 3 of Yeast NOT1 CN9BD-CAF40 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br2272 b:0.9 occ:0.29 BR3 A:TBR2272 0.0 0.9 0.3 TA1 A:TBR2272 2.6 0.1 0.3 TA5 A:TBR2272 2.6 0.1 0.3 BR6 A:TBR2272 3.6 0.7 0.3 BR4 A:TBR2272 3.6 0.7 0.3 BRB A:TBR2272 3.6 0.9 0.3 BR2 A:TBR2272 3.6 0.5 0.3 TA6 A:TBR2272 4.2 0.9 0.3 TA3 A:TBR2272 4.2 0.5 0.3 CB A:GLN1149 4.9 55.2 1.0 OE1 A:GLU1202 4.9 97.0 1.0

Bromine binding site 4 out of 36 in the Yeast NOT1 CN9BD-CAF40 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 4 of Yeast NOT1 CN9BD-CAF40 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br2272 b:0.7 occ:0.29 BR4 A:TBR2272 0.0 0.7 0.3 TA6 A:TBR2272 2.6 0.9 0.3 TA1 A:TBR2272 2.6 0.1 0.3 BR3 A:TBR2272 3.6 0.9 0.3 BRB A:TBR2272 3.6 0.9 0.3 BRC A:TBR2272 3.7 0.6 0.3 BR1 A:TBR2272 3.7 0.1 0.3 TA5 A:TBR2272 4.2 0.1 0.3 CE A:MET1206 4.2 65.4 1.0 TA2 A:TBR2272 4.2 0.5 0.3 SD A:MET1206 4.5 64.2 1.0 CD A:ARG1145 4.6 77.2 1.0

Bromine binding site 5 out of 36 in the Yeast NOT1 CN9BD-CAF40 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 5 of Yeast NOT1 CN9BD-CAF40 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br2272 b:0.4 occ:0.29 BR5 A:TBR2272 0.0 0.4 0.3 TA2 A:TBR2272 2.6 0.5 0.3 TA3 A:TBR2272 2.6 0.5 0.3 BR1 A:TBR2272 3.6 0.1 0.3 BRA A:TBR2272 3.6 0.6 0.3 BR9 A:TBR2272 3.6 0.6 0.3 BR2 A:TBR2272 3.6 0.5 0.3 TA4 A:TBR2272 4.2 0.1 0.3 TA1 A:TBR2272 4.2 0.1 0.3

Bromine binding site 6 out of 36 in the Yeast NOT1 CN9BD-CAF40 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 6 of Yeast NOT1 CN9BD-CAF40 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br2272 b:0.7 occ:0.29 BR6 A:TBR2272 0.0 0.7 0.3 TA5 A:TBR2272 2.6 0.1 0.3 TA3 A:TBR2272 2.6 0.5 0.3 BR3 A:TBR2272 3.6 0.9 0.3 BR7 A:TBR2272 3.6 0.9 0.3 BR2 A:TBR2272 3.6 0.5 0.3 BRA A:TBR2272 3.7 0.6 0.3 TA1 A:TBR2272 4.1 0.1 0.3 TA4 A:TBR2272 4.2 0.1 0.3

Bromine binding site 7 out of 36 in the Yeast NOT1 CN9BD-CAF40 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 7 of Yeast NOT1 CN9BD-CAF40 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br2272 b:0.9 occ:0.29 BR7 A:TBR2272 0.0 0.9 0.3 TA5 A:TBR2272 2.6 0.1 0.3 TA4 A:TBR2272 2.6 0.1 0.3 BR8 A:TBR2272 3.6 0.0 0.3 BRB A:TBR2272 3.6 0.9 0.3 BR6 A:TBR2272 3.6 0.7 0.3 BRA A:TBR2272 3.7 0.6 0.3 TA6 A:TBR2272 4.2 0.9 0.3 TA3 A:TBR2272 4.2 0.5 0.3

Bromine binding site 8 out of 36 in the Yeast NOT1 CN9BD-CAF40 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 8 of Yeast NOT1 CN9BD-CAF40 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br2272 b:0.0 occ:0.29 BR8 A:TBR2272 0.0 0.0 0.3 TA4 A:TBR2272 2.6 0.1 0.3 TA6 A:TBR2272 2.6 0.9 0.3 BR7 A:TBR2272 3.6 0.9 0.3 BR9 A:TBR2272 3.6 0.6 0.3 BRC A:TBR2272 3.6 0.6 0.3 BRB A:TBR2272 3.6 0.9 0.3 TA5 A:TBR2272 4.2 0.1 0.3 TA2 A:TBR2272 4.2 0.5 0.3 O D:GLU351 4.9 0.6 1.0 CB D:GLU351 4.9 0.1 1.0

Bromine binding site 9 out of 36 in the Yeast NOT1 CN9BD-CAF40 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 9 of Yeast NOT1 CN9BD-CAF40 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br2272 b:0.6 occ:0.29 BR9 A:TBR2272 0.0 0.6 0.3 TA4 A:TBR2272 2.6 0.1 0.3 TA2 A:TBR2272 2.6 0.5 0.3 BRC A:TBR2272 3.6 0.6 0.3 BRA A:TBR2272 3.6 0.6 0.3 BR5 A:TBR2272 3.6 0.4 0.3 BR8 A:TBR2272 3.6 0.0 0.3 TA6 A:TBR2272 4.2 0.9 0.3 TA3 A:TBR2272 4.2 0.5 0.3

Bromine binding site 10 out of 36 in the Yeast NOT1 CN9BD-CAF40 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 10 of Yeast NOT1 CN9BD-CAF40 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Br2272 b:0.6 occ:0.29 BRA A:TBR2272 0.0 0.6 0.3 TA3 A:TBR2272 2.6 0.5 0.3 TA4 A:TBR2272 2.6 0.1 0.3 BR9 A:TBR2272 3.6 0.6 0.3 BR5 A:TBR2272 3.6 0.4 0.3 BR6 A:TBR2272 3.7 0.7 0.3 BR7 A:TBR2272 3.7 0.9 0.3 TA2 A:TBR2272 4.2 0.5 0.3 TA5 A:TBR2272 4.2 0.1 0.3

H.Mathys, J.Basquin, S.Ozgur, M.Czarnocki-Cieciura, F.Bonneau, A.Aartse, A.Dziembowski, M.Nowotny, E.Conti, W.Filipowicz. Structural and Biochemical Insights to the Role of the CCR4-Not Complex and DDX6 Atpase in Microrna Repression. Mol.Cell V. 54 751 2014.
ISSN: ISSN 1097-2765
PubMed: 24768538
DOI: 10.1016/J.MOLCEL.2014.03.036