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Atomistry » Bromine » PDB 4i2a-4kk6 » 4k60 » |
Bromine in PDB 4k60: Crystal Structure of Human Chymase in Complex with Fragment 6-Bromo-1, 3-Dihydro-2H-Indol-2-OneEnzymatic activity of Crystal Structure of Human Chymase in Complex with Fragment 6-Bromo-1, 3-Dihydro-2H-Indol-2-One
All present enzymatic activity of Crystal Structure of Human Chymase in Complex with Fragment 6-Bromo-1, 3-Dihydro-2H-Indol-2-One:
3.4.21.39; Protein crystallography data
The structure of Crystal Structure of Human Chymase in Complex with Fragment 6-Bromo-1, 3-Dihydro-2H-Indol-2-One, PDB code: 4k60
was solved by
B.K.Collins,
A.K.Padyana,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4k60:
The structure of Crystal Structure of Human Chymase in Complex with Fragment 6-Bromo-1, 3-Dihydro-2H-Indol-2-One also contains other interesting chemical elements:
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of Human Chymase in Complex with Fragment 6-Bromo-1, 3-Dihydro-2H-Indol-2-One
(pdb code 4k60). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of Human Chymase in Complex with Fragment 6-Bromo-1, 3-Dihydro-2H-Indol-2-One, PDB code: 4k60: Bromine binding site 1 out of 1 in 4k60Go back to Bromine Binding Sites List in 4k60
Bromine binding site 1 out
of 1 in the Crystal Structure of Human Chymase in Complex with Fragment 6-Bromo-1, 3-Dihydro-2H-Indol-2-One
Mono view Stereo pair view
Reference:
S.J.Taylor,
A.K.Padyana,
A.Abeywardane,
S.Liang,
M.H.Hao,
S.De Lombaert,
J.Proudfoot,
B.S.Farmer,
X.Li,
B.Collins,
L.Martin,
D.R.Albaugh,
M.Hill-Drzewi,
S.S.Pullen,
H.Takahashi.
Discovery of Potent, Selective Chymase Inhibitors Via Fragment Linking Strategies. J.Med.Chem. V. 56 4465 2013.
Page generated: Wed Jul 10 21:44:23 2024
ISSN: ISSN 0022-2623 PubMed: 23659209 DOI: 10.1021/JM400138Z |
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