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Atomistry » Bromine » PDB 4mye-4p5b » 4nfn | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Bromine » PDB 4mye-4p5b » 4nfn » |
Bromine in PDB 4nfn: Human Tau Tubulin Kinase 1 (TTBK1) Complexed with 3-({5-[(4-Amino-4- Methylpiperidin-1-Yl)Methyl]Pyrrolo[2,1-F][1,2,4]Triazin-4-Yl}Amino)- 5-BromophenolEnzymatic activity of Human Tau Tubulin Kinase 1 (TTBK1) Complexed with 3-({5-[(4-Amino-4- Methylpiperidin-1-Yl)Methyl]Pyrrolo[2,1-F][1,2,4]Triazin-4-Yl}Amino)- 5-Bromophenol
All present enzymatic activity of Human Tau Tubulin Kinase 1 (TTBK1) Complexed with 3-({5-[(4-Amino-4- Methylpiperidin-1-Yl)Methyl]Pyrrolo[2,1-F][1,2,4]Triazin-4-Yl}Amino)- 5-Bromophenol:
2.7.11.1; Protein crystallography data
The structure of Human Tau Tubulin Kinase 1 (TTBK1) Complexed with 3-({5-[(4-Amino-4- Methylpiperidin-1-Yl)Methyl]Pyrrolo[2,1-F][1,2,4]Triazin-4-Yl}Amino)- 5-Bromophenol, PDB code: 4nfn
was solved by
S.Sheriff,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the Human Tau Tubulin Kinase 1 (TTBK1) Complexed with 3-({5-[(4-Amino-4- Methylpiperidin-1-Yl)Methyl]Pyrrolo[2,1-F][1,2,4]Triazin-4-Yl}Amino)- 5-Bromophenol
(pdb code 4nfn). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Human Tau Tubulin Kinase 1 (TTBK1) Complexed with 3-({5-[(4-Amino-4- Methylpiperidin-1-Yl)Methyl]Pyrrolo[2,1-F][1,2,4]Triazin-4-Yl}Amino)- 5-Bromophenol, PDB code: 4nfn: Bromine binding site 1 out of 1 in 4nfnGo back to Bromine Binding Sites List in 4nfn
Bromine binding site 1 out
of 1 in the Human Tau Tubulin Kinase 1 (TTBK1) Complexed with 3-({5-[(4-Amino-4- Methylpiperidin-1-Yl)Methyl]Pyrrolo[2,1-F][1,2,4]Triazin-4-Yl}Amino)- 5-Bromophenol
Mono view Stereo pair view
Reference:
S.E.Kiefer,
C.J.Chang,
S.R.Kimura,
M.Gao,
D.Xie,
Y.Zhang,
G.Zhang,
M.B.Gill,
H.Mastalerz,
L.A.Thompson,
A.M.Cacace,
S.Sheriff.
The Structure of Human Tau-Tubulin Kinase 1 Both in the Apo Form and in Complex with An Inhibitor. Acta Crystallogr F Struct V. 70 173 2014BIOL Commun.
Page generated: Sat Dec 12 02:21:48 2020
ISSN: ISSN 1744-3091 PubMed: 24637750 DOI: 10.1107/S2053230X14000144 |
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