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Atomistry » Bromine » PDB 4x6i-4z8b » 4xy9 » |
Bromine in PDB 4xy9: Crystal Structure of the First Bromodomain of Human BRD4 in Complex with A 2-Amine-9H-Purine LigandProtein crystallography data
The structure of Crystal Structure of the First Bromodomain of Human BRD4 in Complex with A 2-Amine-9H-Purine Ligand, PDB code: 4xy9
was solved by
S.Picaud,
F.Von Delft,
A.M.Edwards,
C.H.Arrowsmith,
C.Bountra,
P.Filippakopoulos,
Structural Genomics Consortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of the First Bromodomain of Human BRD4 in Complex with A 2-Amine-9H-Purine Ligand
(pdb code 4xy9). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of the First Bromodomain of Human BRD4 in Complex with A 2-Amine-9H-Purine Ligand, PDB code: 4xy9: Bromine binding site 1 out of 1 in 4xy9Go back to Bromine Binding Sites List in 4xy9
Bromine binding site 1 out
of 1 in the Crystal Structure of the First Bromodomain of Human BRD4 in Complex with A 2-Amine-9H-Purine Ligand
Mono view Stereo pair view
Reference:
S.Picaud,
M.Strocchia,
S.Terracciano,
G.Lauro,
J.Mendez,
D.L.Daniels,
R.Riccio,
G.Bifulco,
I.Bruno,
P.Filippakopoulos.
The 9H-Purine Scaffold Reveals Induced-Fit Pocket Plasticity of the BRD9 Bromodomain. J.Med.Chem. 2015.
Page generated: Sat Dec 12 02:23:58 2020
ISSN: ISSN 0022-2623 PubMed: 25703523 DOI: 10.1021/JM501893K |
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