Bromine in PDB 5ev1: Structure I of Intact U2AF65 Recognizing A 3' Splice Site Signal

The structure of Structure I of Intact U2AF65 Recognizing A 3' Splice Site Signal, PDB code: 5ev1 was solved by A.A.Agrawal, J.L.Jenkins, C.L.Kielkopf, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.46 / 2.04
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	62.052, 114.241, 59.418, 90.00, 90.00, 90.00
R / Rfree (%)	17.3 / 22.8

The structure of Structure I of Intact U2AF65 Recognizing A 3' Splice Site Signal also contains other interesting chemical elements:

Sodium

(Na)

2 atoms

The binding sites of Bromine atom in the Structure I of Intact U2AF65 Recognizing A 3' Splice Site Signal (pdb code 5ev1). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Structure I of Intact U2AF65 Recognizing A 3' Splice Site Signal, PDB code: 5ev1:

Bromine binding site 1 out of 1 in the Structure I of Intact U2AF65 Recognizing A 3' Splice Site Signal


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Structure I of Intact U2AF65 Recognizing A 3' Splice Site Signal within 5.0Å range: probe atom residue distance (Å) B Occ B:Br7 b:63.6 occ:1.00 BR B:BRU7 0.0 63.6 1.0 C5 B:BRU7 1.9 40.9 1.0 C6 B:BRU7 2.8 31.9 1.0 OP1 B:DU6 3.0 31.9 1.0 C4 B:BRU7 3.0 29.2 1.0 O4 B:BRU7 3.2 28.6 1.0 O B:HOH204 3.2 41.6 1.0 O B:HOH207 3.6 38.6 1.0 CE2 A:TYR152 3.6 30.7 1.0 HE2 A:TYR152 3.7 36.9 1.0 CZ A:TYR152 3.7 28.9 1.0 P B:DU6 3.8 38.1 1.0 HE1 A:HIS230 3.9 55.6 1.0 HH A:TYR152 3.9 35.8 1.0 HE2 A:HIS230 3.9 55.8 1.0 OH A:TYR152 4.0 29.8 1.0 OP2 B:DU6 4.0 36.5 1.0 N1 B:BRU7 4.1 32.5 1.0 CD2 A:TYR152 4.2 30.4 1.0 HG3 A:ARG227 4.2 37.7 1.0 N3 B:BRU7 4.2 28.9 1.0 CE1 A:HIS230 4.3 46.3 1.0 OP2 B:BRU7 4.3 43.1 1.0 NE2 A:HIS230 4.3 46.5 1.0 CE1 A:TYR152 4.4 27.5 1.0 O5' B:DU6 4.5 37.1 1.0 HD2 A:TYR152 4.5 36.5 1.0 O5' B:BRU7 4.5 39.0 1.0 C2 B:BRU7 4.6 30.9 1.0 C5' B:DU6 4.6 35.1 1.0 C3' B:DU6 4.7 36.2 1.0 CG A:TYR152 4.7 31.2 1.0 CD1 A:TYR152 4.8 29.7 1.0 HE1 A:TYR152 4.8 33.0 1.0 HB2 A:ARG227 4.9 30.9 1.0

A.A.Agrawal, E.Salsi, R.Chatrikhi, S.Henderson, J.L.Jenkins, M.R.Green, D.N.Ermolenko, C.L.Kielkopf. An Extended U2AF(65)-Rna-Binding Domain Recognizes the 3' Splice Site Signal. Nat Commun V. 7 10950 2016.
ISSN: ESSN 2041-1723
PubMed: 26952537
DOI: 10.1038/NCOMMS10950