Bromine in PDB 5f9z: Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp

The structure of Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp, PDB code: 5f9z was solved by Seattle Structural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.61 / 2.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	89.400, 108.720, 126.350, 90.00, 90.00, 90.00
R / Rfree (%)	20.8 / 23.4

The structure of Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp also contains other interesting chemical elements:

Chlorine	(Cl)	2 atoms
Zinc	(Zn)	2 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Bromine atom in the Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp (pdb code 5f9z). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp, PDB code: 5f9z:
Jump to Bromine binding site number: 1; 2;

Bromine binding site 1 out of 2 in the Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp within 5.0Å range: probe atom residue distance (Å) B Occ A:Br702 b:55.6 occ:1.00 BR1 A:HFG702 0.0 55.6 1.0 C7 A:HFG702 2.0 46.0 1.0 C6 A:HFG702 2.9 42.8 1.0 C8 A:HFG702 2.9 41.2 1.0 O A:PHE276 3.2 84.0 1.0 CL1 A:HFG702 3.3 43.5 1.0 CG2 A:VAL280 3.4 33.0 1.0 CB A:GLU279 3.8 38.7 1.0 CB A:PRO299 3.8 31.2 1.0 N A:PHE276 3.9 93.9 1.0 N A:VAL280 3.9 36.6 1.0 CG A:PRO299 3.9 31.5 1.0 C A:PHE276 4.0 86.2 1.0 C A:GLU279 4.1 39.1 1.0 C5 A:HFG702 4.2 39.9 1.0 C9 A:HFG702 4.2 38.2 1.0 CA A:VAL280 4.3 34.5 1.0 OE1 A:GLU279 4.3 37.8 1.0 CB A:VAL280 4.4 34.2 1.0 CA A:GLU279 4.4 40.7 1.0 O A:GLU279 4.5 38.0 1.0 CA A:PHE276 4.5 91.8 1.0 C10 A:HFG702 4.7 38.3 1.0 CA A:GLY275 4.8 89.5 1.0 C A:GLY275 4.8 91.9 1.0 N A:GLU279 4.8 45.2 1.0 CG A:GLU279 4.9 38.7 1.0

Bromine binding site 2 out of 2 in the Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp within 5.0Å range: probe atom residue distance (Å) B Occ B:Br703 b:52.7 occ:1.00 BR1 B:HFG703 0.0 52.7 1.0 C7 B:HFG703 2.0 42.0 1.0 C8 B:HFG703 2.9 36.4 1.0 C6 B:HFG703 2.9 39.0 1.0 CL1 B:HFG703 3.3 40.9 1.0 CG2 B:VAL280 3.4 39.3 1.0 CG B:PRO299 3.6 37.2 1.0 CB B:PRO299 3.7 36.2 1.0 CB B:SER277 3.8 52.2 1.0 CB B:GLU279 3.9 37.2 1.0 OG B:SER277 3.9 53.7 1.0 N B:VAL280 4.2 36.2 1.0 OE1 B:GLU279 4.2 36.9 1.0 C5 B:HFG703 4.2 35.4 1.0 C9 B:HFG703 4.2 32.6 1.0 C B:GLU279 4.3 35.8 1.0 CA B:VAL280 4.5 34.6 1.0 CB B:VAL280 4.6 39.7 1.0 CA B:GLU279 4.6 45.1 1.0 O B:GLU279 4.7 34.2 1.0 C10 B:HFG703 4.7 32.9 1.0 CD1 B:PHE276 4.8 60.6 1.0 CE1 B:PHE276 4.8 60.6 1.0 N B:GLU279 4.9 45.9 1.0 CG B:GLU279 4.9 39.2 1.0

Seattle Structural Genomics Center For Infectious Disease(Ssgcid), D.M.Dranow, D.Fox Iii, D.Lorimer, T.E.Edwards. Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp To Be Published.