Bromine in PDB 5h2z: Crystal Structure of Human Dihydroorotate Dehydrogenase (Dhodh) with 7GF

All present enzymatic activity of Crystal Structure of Human Dihydroorotate Dehydrogenase (Dhodh) with 7GF:
1.3.5.2;

The structure of Crystal Structure of Human Dihydroorotate Dehydrogenase (Dhodh) with 7GF, PDB code: 5h2z was solved by D.Wu, J.Huang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.40 / 1.58
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	90.875, 90.875, 123.170, 90.00, 90.00, 120.00
R / Rfree (%)	17 / 18.6

The binding sites of Bromine atom in the Crystal Structure of Human Dihydroorotate Dehydrogenase (Dhodh) with 7GF (pdb code 5h2z). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of Human Dihydroorotate Dehydrogenase (Dhodh) with 7GF, PDB code: 5h2z:

Bromine binding site 1 out of 1 in the Crystal Structure of Human Dihydroorotate Dehydrogenase (Dhodh) with 7GF


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of Human Dihydroorotate Dehydrogenase (Dhodh) with 7GF within 5.0Å range: probe atom residue distance (Å) B Occ A:Br407 b:30.9 occ:1.00 BR A:7GF407 0.0 30.9 1.0 C16 A:7GF407 2.0 18.7 1.0 C17 A:7GF407 2.8 26.5 1.0 C15 A:7GF407 2.8 23.9 1.0 CB A:ALA59 3.9 19.8 1.0 C18 A:7GF407 4.1 28.1 1.0 C14 A:7GF407 4.1 25.9 1.0 CD A:PRO364 4.1 21.2 1.0 CE1 A:PHE98 4.2 25.6 1.0 CG A:PRO364 4.2 21.4 1.0 CB A:LEU359 4.3 21.1 1.0 CD1 A:LEU359 4.3 28.2 1.0 CZ A:PHE98 4.3 26.4 1.0 CD2 A:LEU359 4.4 23.1 1.0 CE A:MET111 4.4 28.3 1.0 CG A:LEU359 4.6 23.0 1.0 C13 A:7GF407 4.7 29.3 1.0 O A:LEU359 4.7 23.3 1.0 OG1 A:THR63 4.7 20.0 1.0 N A:PRO364 4.8 22.2 1.0

J.Huang, D.Wu. Crystal Structure of Human Dihydroorotate Dehydrogenase (Dhodh) with 7GF To Be Published.