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Atomistry » Bromine » PDB 5ev3-5i5p » 5hex » |
Bromine in PDB 5hex: Crystal Structure of Human Hexokinase 2 with Cmpd 30, A 2-Amino-6- Benzenesulfonamide GlucosamineEnzymatic activity of Crystal Structure of Human Hexokinase 2 with Cmpd 30, A 2-Amino-6- Benzenesulfonamide Glucosamine
All present enzymatic activity of Crystal Structure of Human Hexokinase 2 with Cmpd 30, A 2-Amino-6- Benzenesulfonamide Glucosamine:
2.7.1.1; Protein crystallography data
The structure of Crystal Structure of Human Hexokinase 2 with Cmpd 30, A 2-Amino-6- Benzenesulfonamide Glucosamine, PDB code: 5hex
was solved by
N.Campobasso,
B.Zhao,
A.Smallwood,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of Human Hexokinase 2 with Cmpd 30, A 2-Amino-6- Benzenesulfonamide Glucosamine
(pdb code 5hex). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total 4 binding sites of Bromine where determined in the Crystal Structure of Human Hexokinase 2 with Cmpd 30, A 2-Amino-6- Benzenesulfonamide Glucosamine, PDB code: 5hex: Jump to Bromine binding site number: 1; 2; 3; 4; Bromine binding site 1 out of 4 in 5hexGo back to Bromine Binding Sites List in 5hex
Bromine binding site 1 out
of 4 in the Crystal Structure of Human Hexokinase 2 with Cmpd 30, A 2-Amino-6- Benzenesulfonamide Glucosamine
Mono view Stereo pair view
Bromine binding site 2 out of 4 in 5hexGo back to Bromine Binding Sites List in 5hex
Bromine binding site 2 out
of 4 in the Crystal Structure of Human Hexokinase 2 with Cmpd 30, A 2-Amino-6- Benzenesulfonamide Glucosamine
Mono view Stereo pair view
Bromine binding site 3 out of 4 in 5hexGo back to Bromine Binding Sites List in 5hex
Bromine binding site 3 out
of 4 in the Crystal Structure of Human Hexokinase 2 with Cmpd 30, A 2-Amino-6- Benzenesulfonamide Glucosamine
Mono view Stereo pair view
Bromine binding site 4 out of 4 in 5hexGo back to Bromine Binding Sites List in 5hex
Bromine binding site 4 out
of 4 in the Crystal Structure of Human Hexokinase 2 with Cmpd 30, A 2-Amino-6- Benzenesulfonamide Glucosamine
Mono view Stereo pair view
Reference:
H.Lin,
J.Zeng,
R.Xie,
M.J.Schulz,
R.Tedesco,
J.Qu,
K.F.Erhard,
J.F.Mack,
K.Raha,
A.R.Rendina,
L.M.Szewczuk,
P.M.Kratz,
A.J.Jurewicz,
T.Cecconie,
S.Martens,
P.J.Mcdevitt,
J.D.Martin,
S.B.Chen,
Y.Jiang,
L.Nickels,
B.J.Schwartz,
A.Smallwood,
B.Zhao,
N.Campobasso,
Y.Qian,
J.Briand,
C.M.Rominger,
C.Oleykowski,
M.A.Hardwicke,
J.I.Luengo.
Discovery of A Novel 2,6-Disubstituted Glucosamine Series of Potent and Selective Hexokinase 2 Inhibitors. Acs Med.Chem.Lett. V. 7 217 2016.
Page generated: Wed Jul 10 23:48:29 2024
ISSN: ISSN 1948-5875 PubMed: 26985301 DOI: 10.1021/ACSMEDCHEMLETT.5B00214 |
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