Bromine in PDB 5il0: Crystal Structural of the METTL3-METTL14 Complex For N6-Adenosine Methylation

All present enzymatic activity of Crystal Structural of the METTL3-METTL14 Complex For N6-Adenosine Methylation:
2.1.1.62;

The structure of Crystal Structural of the METTL3-METTL14 Complex For N6-Adenosine Methylation, PDB code: 5il0 was solved by X.Wang, Z.Guan, T.Zou, P.Yin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.27 / 1.88
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	101.695, 101.695, 116.478, 90.00, 90.00, 90.00
R / Rfree (%)	17.5 / 20.5

The binding sites of Bromine atom in the Crystal Structural of the METTL3-METTL14 Complex For N6-Adenosine Methylation (pdb code 5il0). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structural of the METTL3-METTL14 Complex For N6-Adenosine Methylation, PDB code: 5il0:

Bromine binding site 1 out of 1 in the Crystal Structural of the METTL3-METTL14 Complex For N6-Adenosine Methylation


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structural of the METTL3-METTL14 Complex For N6-Adenosine Methylation within 5.0Å range: probe atom residue distance (Å) B Occ B:Br502 b:38.5 occ:1.00 NZ B:LYS250 3.4 24.8 1.0 N B:ASP222 3.5 21.9 1.0 CB B:ASP222 3.5 36.9 1.0 N B:ILE221 3.8 22.8 1.0 CD1 B:TRP251 3.8 19.6 1.0 CA B:GLU220 3.8 23.5 1.0 C B:GLU220 3.9 24.5 1.0 CE B:LYS250 4.0 25.5 1.0 O B:LEU219 4.1 24.0 1.0 CA B:ASP222 4.1 30.9 1.0 CD B:LYS250 4.1 18.8 1.0 O B:LYS250 4.1 23.3 1.0 CA B:TRP251 4.1 22.3 1.0 C B:ILE221 4.5 24.3 1.0 CB B:GLU220 4.6 26.9 1.0 O B:GLU220 4.6 26.1 1.0 CA B:ILE221 4.6 20.7 1.0 CG B:TRP251 4.7 19.0 1.0 O B:TRP251 4.7 23.1 1.0 C B:LYS250 4.8 21.4 1.0 CB B:TRP251 4.8 19.5 1.0 NE1 B:TRP251 4.8 22.9 1.0 C B:TRP251 4.8 26.5 1.0 N B:TRP251 4.8 19.8 1.0 CG B:ASP222 4.8 49.6 1.0 N B:GLU220 4.9 26.2 1.0 C B:LEU219 4.9 26.1 1.0 N B:GLU223 4.9 23.8 1.0 C B:ASP222 5.0 31.2 1.0

X.Wang, J.Feng, Y.Xue, Z.Guan, D.Zhang, Z.Liu, Z.Gong, Q.Wang, J.Huang, C.Tang, T.Zou, P.Yin. Structural Basis of N6-Adenosine Methylation By the METTL3-METTL14 Complex Nature V. 534 575 2016.
ISSN: ISSN 0028-0836
PubMed: 27281194
DOI: 10.1038/NATURE18298