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Atomistry » Bromine » PDB 5o62-5q0c » 5q06 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Bromine » PDB 5o62-5q0c » 5q06 » |
Bromine in PDB 5q06: Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(5-Bromo-1,3-Thiazol-2-Yl)-3-[4-(2-Methyl-1,3-Thiazol-4-Yl) Phenyl]SulfonylureaEnzymatic activity of Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(5-Bromo-1,3-Thiazol-2-Yl)-3-[4-(2-Methyl-1,3-Thiazol-4-Yl) Phenyl]Sulfonylurea
All present enzymatic activity of Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(5-Bromo-1,3-Thiazol-2-Yl)-3-[4-(2-Methyl-1,3-Thiazol-4-Yl) Phenyl]Sulfonylurea:
3.1.3.11; Protein crystallography data
The structure of Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(5-Bromo-1,3-Thiazol-2-Yl)-3-[4-(2-Methyl-1,3-Thiazol-4-Yl) Phenyl]Sulfonylurea, PDB code: 5q06
was solved by
A.Ruf,
C.Joseph,
A.Alker,
D.Banner,
T.Tetaz,
J.Benz,
B.Kuhn,
M.G.Rudolph,
H.Yang,
C.Shao,
S.K.Burley,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Bromine Binding Sites:
The binding sites of Bromine atom in the Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(5-Bromo-1,3-Thiazol-2-Yl)-3-[4-(2-Methyl-1,3-Thiazol-4-Yl) Phenyl]Sulfonylurea
(pdb code 5q06). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total 4 binding sites of Bromine where determined in the Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(5-Bromo-1,3-Thiazol-2-Yl)-3-[4-(2-Methyl-1,3-Thiazol-4-Yl) Phenyl]Sulfonylurea, PDB code: 5q06: Jump to Bromine binding site number: 1; 2; 3; 4; Bromine binding site 1 out of 4 in 5q06Go back to Bromine Binding Sites List in 5q06
Bromine binding site 1 out
of 4 in the Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(5-Bromo-1,3-Thiazol-2-Yl)-3-[4-(2-Methyl-1,3-Thiazol-4-Yl) Phenyl]Sulfonylurea
Mono view Stereo pair view
Bromine binding site 2 out of 4 in 5q06Go back to Bromine Binding Sites List in 5q06
Bromine binding site 2 out
of 4 in the Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(5-Bromo-1,3-Thiazol-2-Yl)-3-[4-(2-Methyl-1,3-Thiazol-4-Yl) Phenyl]Sulfonylurea
Mono view Stereo pair view
Bromine binding site 3 out of 4 in 5q06Go back to Bromine Binding Sites List in 5q06
Bromine binding site 3 out
of 4 in the Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(5-Bromo-1,3-Thiazol-2-Yl)-3-[4-(2-Methyl-1,3-Thiazol-4-Yl) Phenyl]Sulfonylurea
Mono view Stereo pair view
Bromine binding site 4 out of 4 in 5q06Go back to Bromine Binding Sites List in 5q06
Bromine binding site 4 out
of 4 in the Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(5-Bromo-1,3-Thiazol-2-Yl)-3-[4-(2-Methyl-1,3-Thiazol-4-Yl) Phenyl]Sulfonylurea
Mono view Stereo pair view
Reference:
A.Ruf,
C.Joseph,
A.Alker,
D.Banner,
T.Tetaz,
J.Benz,
B.Kuhn,
M.G.Rudolph.
Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(5-Bromo-1,3-Thiazol-2-Yl)-3-[4-(2-Methyl-1, 3-Thiazol-4-Yl)Phenyl]Sulfonylurea To Be Published.
Page generated: Thu Jul 11 00:44:35 2024
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