Bromine in PDB 5t5a: Crystal Structure of the Twister Sister (Ts) Ribozyme at 2.0 Angstrom

The structure of Crystal Structure of the Twister Sister (Ts) Ribozyme at 2.0 Angstrom, PDB code: 5t5a was solved by D.M.J.Lilley, Y.Liu, T.J.Wilson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.16 / 2.00
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	39.304, 39.304, 228.413, 90.00, 90.00, 90.00
R / Rfree (%)	17 / 21.7

The structure of Crystal Structure of the Twister Sister (Ts) Ribozyme at 2.0 Angstrom also contains other interesting chemical elements:

Magnesium

(Mg)

9 atoms

The binding sites of Bromine atom in the Crystal Structure of the Twister Sister (Ts) Ribozyme at 2.0 Angstrom (pdb code 5t5a). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Crystal Structure of the Twister Sister (Ts) Ribozyme at 2.0 Angstrom, PDB code: 5t5a:
Jump to Bromine binding site number: 1; 2;

Bromine binding site 1 out of 2 in the Crystal Structure of the Twister Sister (Ts) Ribozyme at 2.0 Angstrom


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of the Twister Sister (Ts) Ribozyme at 2.0 Angstrom within 5.0Å range: probe atom residue distance (Å) B Occ A:Br37 b:44.7 occ:1.00 BR A:CBV37 0.0 44.7 1.0 C5 A:CBV37 1.9 40.2 1.0 C6 A:CBV37 2.8 40.0 1.0 C4 A:CBV37 2.9 38.0 1.0 N4 A:CBV37 3.0 37.4 1.0 N7 A:G36 3.4 35.1 1.0 C5 A:G36 3.5 33.5 1.0 C8 A:G36 3.6 36.7 1.0 O2P A:CBV37 3.8 46.3 1.0 C4 A:G36 3.8 33.4 1.0 N9 A:G36 3.9 36.2 1.0 C6 A:G36 4.1 31.7 1.0 N3 A:CBV37 4.1 37.1 1.0 N1 A:CBV37 4.1 39.0 1.0 C3' A:G36 4.4 42.8 1.0 C2' A:G36 4.5 41.9 1.0 O6 A:G36 4.5 31.5 1.0 O5' A:CBV37 4.6 44.4 1.0 C2 A:CBV37 4.6 37.1 1.0 C5 A:C38 4.6 32.7 1.0 N3 A:G36 4.6 31.5 1.0 N1 A:G36 4.7 30.9 1.0 C1' A:G36 4.8 39.4 1.0 P A:CBV37 4.8 45.6 1.0 C2 A:G36 5.0 31.0 1.0

Bromine binding site 2 out of 2 in the Crystal Structure of the Twister Sister (Ts) Ribozyme at 2.0 Angstrom


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Crystal Structure of the Twister Sister (Ts) Ribozyme at 2.0 Angstrom within 5.0Å range: probe atom residue distance (Å) B Occ A:Br39 b:32.6 occ:1.00 BR A:CBV39 0.0 32.6 1.0 C5 A:CBV39 1.9 30.0 1.0 C6 A:CBV39 2.8 29.6 1.0 C4 A:CBV39 3.0 28.7 1.0 N4 A:CBV39 3.2 28.8 1.0 C5 A:C38 3.5 32.7 1.0 C4 A:C38 3.6 32.6 1.0 C6 A:C38 3.6 33.5 1.0 O A:HOH303 3.7 41.2 1.0 N3 A:C38 3.8 33.1 1.0 O1P A:CBV39 3.8 36.0 1.0 N1 A:C38 3.9 34.6 1.0 C2 A:C38 3.9 33.9 1.0 N1 A:CBV39 4.1 29.0 1.0 N4 A:C38 4.1 33.2 1.0 N3 A:CBV39 4.2 28.3 1.0 C5 A:C40 4.3 29.1 1.0 C2' A:C38 4.4 37.7 1.0 C3' A:C38 4.5 38.2 1.0 O5' A:CBV39 4.6 33.4 1.0 C2 A:CBV39 4.7 28.3 1.0 O2 A:C38 4.7 33.1 1.0 C1' A:C38 4.8 36.3 1.0 P A:CBV39 4.8 36.0 1.0 C6 A:C40 5.0 31.1 1.0

Y.Liu, T.J.Wilson, D.M.Lilley. The Structure of A Nucleolytic Ribozyme That Employs A Catalytic Metal Ion. Nat. Chem. Biol. V. 13 508 2017.
ISSN: ESSN 1552-4469
PubMed: 28263963
DOI: 10.1038/NCHEMBIO.2333