Atomistry » Bromine » PDB 5y94-6c2x » 5yc7
Atomistry »
  Bromine »
    PDB 5y94-6c2x »
      5yc7 »

Bromine in PDB 5yc7: The Crystal Structure of Upa in Complex with 4-Bromobenzylamirne at PH7.4

Enzymatic activity of The Crystal Structure of Upa in Complex with 4-Bromobenzylamirne at PH7.4

All present enzymatic activity of The Crystal Structure of Upa in Complex with 4-Bromobenzylamirne at PH7.4:
3.4.21.73;

Protein crystallography data

The structure of The Crystal Structure of Upa in Complex with 4-Bromobenzylamirne at PH7.4, PDB code: 5yc7 was solved by L.G.Jiang, X.Zhang, M.D.Huang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 60.79 / 2.00
Space group H 3
Cell size a, b, c (Å), α, β, γ (°) 121.575, 121.575, 42.212, 90.00, 90.00, 120.00
R / Rfree (%) 21.2 / 26.2

Bromine Binding Sites:

The binding sites of Bromine atom in the The Crystal Structure of Upa in Complex with 4-Bromobenzylamirne at PH7.4 (pdb code 5yc7). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the The Crystal Structure of Upa in Complex with 4-Bromobenzylamirne at PH7.4, PDB code: 5yc7:

Bromine binding site 1 out of 1 in 5yc7

Go back to Bromine Binding Sites List in 5yc7
Bromine binding site 1 out of 1 in the The Crystal Structure of Upa in Complex with 4-Bromobenzylamirne at PH7.4


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of The Crystal Structure of Upa in Complex with 4-Bromobenzylamirne at PH7.4 within 5.0Å range:
probe atom residue distance (Å) B Occ
U:Br301

b:0.6
occ:1.00
BR U:PZH301 0.0 0.6 1.0
CZ U:PZH301 1.9 94.2 1.0
CE1 U:PZH301 2.8 90.0 1.0
CE2 U:PZH301 2.9 87.0 1.0
OD2 U:ASP189 3.0 54.3 1.0
O U:SER190 3.3 52.0 1.0
OD1 U:ASP189 3.3 45.2 1.0
CG U:ASP189 3.4 49.1 1.0
OG U:SER190 3.4 48.2 1.0
O U:GLY219 3.6 55.5 1.0
CA U:GLY226 3.8 52.2 1.0
C U:SER190 4.0 46.3 1.0
CA U:GLY216 4.1 60.2 1.0
CD1 U:PZH301 4.1 83.8 1.0
CD2 U:PZH301 4.2 81.2 1.0
N U:GLY226 4.4 56.0 1.0
N U:GLY216 4.5 55.6 1.0
N U:SER190 4.5 46.1 1.0
CB U:SER190 4.5 48.0 1.0
O U:TRP215 4.5 53.8 1.0
CA U:SER190 4.6 45.9 1.0
CA U:CYS220 4.6 56.3 1.0
CB U:ASP189 4.6 47.2 1.0
CG U:PZH301 4.7 77.9 1.0
C U:GLY219 4.7 60.7 1.0
C U:TRP215 4.7 51.4 1.0
N U:CYS191 4.8 43.5 1.0
C U:GLY216 4.8 67.8 1.0
O U:PRO225 4.9 60.7 1.0
C U:PRO225 4.9 62.8 1.0

Reference:

L.G.Jiang, X.Zhang, Y.Zhou, Y.Y.Chen, Z.P.Luo, J.Y.Li, C.Yuan, M.D.Huang. Halogen Bonding For the Design of Inhibitors By Targeting the S1 Pocket of Serine Proteases Rsc Adv V. 8 28189 2018.
ISSN: ESSN 2046-2069
DOI: 10.1039/C8RA03145B
Page generated: Mon Jul 7 09:28:13 2025

Last articles

Ca in 1GPL
Ca in 1GP7
Ca in 1GKC
Ca in 1GKD
Ca in 1GN1
Ca in 1GMM
Ca in 1GM9
Ca in 1GM8
Ca in 1GLG
Ca in 1GM7
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy