Bromine in PDB 6a1c: Crystal Structure of the CK2A1-GO289 Complex

Enzymatic activity of Crystal Structure of the CK2A1-GO289 Complex

All present enzymatic activity of Crystal Structure of the CK2A1-GO289 Complex:
2.7.11.1;

Protein crystallography data

The structure of Crystal Structure of the CK2A1-GO289 Complex, PDB code: 6a1c was solved by T.Kinoshita, M.Tsuyuguchi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 55.94 / 1.68
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 51.657, 78.831, 79.403, 90.00, 90.00, 90.00
R / Rfree (%) 13.8 / 19.6

Other elements in 6a1c:

The structure of Crystal Structure of the CK2A1-GO289 Complex also contains other interesting chemical elements:

Sodium (Na) 1 atom

Bromine Binding Sites:

The binding sites of Bromine atom in the Crystal Structure of the CK2A1-GO289 Complex (pdb code 6a1c). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total only one binding site of Bromine was determined in the Crystal Structure of the CK2A1-GO289 Complex, PDB code: 6a1c:

Bromine binding site 1 out of 1 in 6a1c

Go back to Bromine Binding Sites List in 6a1c
Bromine binding site 1 out of 1 in the Crystal Structure of the CK2A1-GO289 Complex


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Crystal Structure of the CK2A1-GO289 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Br401

b:29.7
occ:1.00
BR9 A:9NX401 0.0 29.7 1.0
C3 A:9NX401 1.8 25.2 1.0
C2 A:9NX401 2.7 27.1 1.0
C4 A:9NX401 2.8 23.1 1.0
C11 A:9NX401 3.2 30.4 1.0
O A:HOH544 3.3 35.4 1.0
CB A:PHE113 3.8 14.3 1.0
CD1 A:ILE95 3.9 11.6 1.0
CG1 A:ILE95 3.9 11.8 1.0
CG A:PHE113 3.9 13.2 1.0
C1 A:9NX401 4.0 27.4 1.0
S19 A:9NX401 4.0 63.6 1.0
C5 A:9NX401 4.1 29.1 1.0
CG2 A:ILE174 4.1 13.4 1.0
CG1 A:VAL66 4.1 18.7 1.0
CD2 A:PHE113 4.1 13.4 1.0
SD A:MET163 4.2 33.0 1.0
CB A:VAL66 4.2 19.2 1.0
O A:GLU114 4.4 16.0 1.0
N12 A:9NX401 4.5 27.6 1.0
CD1 A:PHE113 4.5 14.5 1.0
C6 A:9NX401 4.5 27.2 1.0
CG2 A:VAL66 4.5 20.0 1.0
CB A:ILE174 4.7 11.2 1.0
CE2 A:PHE113 4.9 16.0 1.0
CD1 A:ILE174 4.9 13.8 1.0
O7 A:9NX401 4.9 29.6 1.0

Reference:

T.Oshima, Y.Niwa, K.Kuwata, A.Srivastava, T.Hyoda, Y.Tsuchiya, M.Kumagai, M.Tsuyuguchi, T.Tamaru, A.Sugiyama, N.Ono, N.Zolboot, Y.Aikawa, S.Oishi, A.Nonami, F.Arai, S.Hagihara, J.Yamaguchi, F.Tama, Y.Kunisaki, K.Yagita, M.Ikeda, T.Kinoshita, S.A.Kay, K.Itami, T.Hirota. Cell-Based Screen Identifies A New Potent and Highly Selective CK2 Inhibitor For Modulation of Circadian Rhythms and Cancer Cell Growth. Sci Adv V. 5 U9060 2019.
ISSN: ESSN 2375-2548
PubMed: 30746467
DOI: 10.1126/SCIADV.AAU9060
Page generated: Sat Dec 12 02:32:03 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy