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Bromine in PDB 6ar4: Crystal Structure of PICK1 in Complex with the Small Molecule Inhibitor 1OProtein crystallography data
The structure of Crystal Structure of PICK1 in Complex with the Small Molecule Inhibitor 1O, PDB code: 6ar4
was solved by
D.Marcotte,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6ar4:
The structure of Crystal Structure of PICK1 in Complex with the Small Molecule Inhibitor 1O also contains other interesting chemical elements:
Bromine Binding Sites:
The binding sites of Bromine atom in the Crystal Structure of PICK1 in Complex with the Small Molecule Inhibitor 1O
(pdb code 6ar4). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Crystal Structure of PICK1 in Complex with the Small Molecule Inhibitor 1O, PDB code: 6ar4: Jump to Bromine binding site number: 1; 2; Bromine binding site 1 out of 2 in 6ar4Go back to Bromine Binding Sites List in 6ar4
Bromine binding site 1 out
of 2 in the Crystal Structure of PICK1 in Complex with the Small Molecule Inhibitor 1O
Mono view Stereo pair view
Bromine binding site 2 out of 2 in 6ar4Go back to Bromine Binding Sites List in 6ar4
Bromine binding site 2 out
of 2 in the Crystal Structure of PICK1 in Complex with the Small Molecule Inhibitor 1O
Mono view Stereo pair view
Reference:
E.Y.S.Lin,
L.F.Silvian,
D.J.Marcotte,
C.C.Banos,
F.Jow,
T.R.Chan,
R.M.Arduini,
F.Qian,
D.P.Baker,
C.Bergeron,
C.A.Hession,
R.L.Huganir,
C.F.Borenstein,
I.Enyedy,
J.Zou,
E.Rohde,
M.Wittmann,
G.Kumaravel,
K.J.Rhodes,
R.H.Scannevin,
A.W.Dunah,
K.M.Guckian.
Potent Pdz-Domain PICK1 Inhibitors That Modulate Amyloid Beta-Mediated Synaptic Dysfunction. Sci Rep V. 8 13438 2018.
Page generated: Sat Dec 12 02:32:10 2020
ISSN: ESSN 2045-2322 PubMed: 30194389 DOI: 10.1038/S41598-018-31680-3 |
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