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Bromine in PDB 6cox: Cyclooxygenase-2 (Prostaglandin Synthase-2) Complexed with A Selective Inhibitor, Sc-558 in I222 Space GroupEnzymatic activity of Cyclooxygenase-2 (Prostaglandin Synthase-2) Complexed with A Selective Inhibitor, Sc-558 in I222 Space Group
All present enzymatic activity of Cyclooxygenase-2 (Prostaglandin Synthase-2) Complexed with A Selective Inhibitor, Sc-558 in I222 Space Group:
1.14.99.1; Protein crystallography data
The structure of Cyclooxygenase-2 (Prostaglandin Synthase-2) Complexed with A Selective Inhibitor, Sc-558 in I222 Space Group, PDB code: 6cox
was solved by
R.Kurumbail,
W.Stallings,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6cox:
The structure of Cyclooxygenase-2 (Prostaglandin Synthase-2) Complexed with A Selective Inhibitor, Sc-558 in I222 Space Group also contains other interesting chemical elements:
Bromine Binding Sites:
The binding sites of Bromine atom in the Cyclooxygenase-2 (Prostaglandin Synthase-2) Complexed with A Selective Inhibitor, Sc-558 in I222 Space Group
(pdb code 6cox). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Cyclooxygenase-2 (Prostaglandin Synthase-2) Complexed with A Selective Inhibitor, Sc-558 in I222 Space Group, PDB code: 6cox: Jump to Bromine binding site number: 1; 2; Bromine binding site 1 out of 2 in 6coxGo back to Bromine Binding Sites List in 6cox
Bromine binding site 1 out
of 2 in the Cyclooxygenase-2 (Prostaglandin Synthase-2) Complexed with A Selective Inhibitor, Sc-558 in I222 Space Group
Mono view Stereo pair view
Bromine binding site 2 out of 2 in 6coxGo back to Bromine Binding Sites List in 6cox
Bromine binding site 2 out
of 2 in the Cyclooxygenase-2 (Prostaglandin Synthase-2) Complexed with A Selective Inhibitor, Sc-558 in I222 Space Group
Mono view Stereo pair view
Reference:
R.G.Kurumbail,
A.M.Stevens,
J.K.Gierse,
J.J.Mcdonald,
R.A.Stegeman,
J.Y.Pak,
D.Gildehaus,
J.M.Miyashiro,
T.D.Penning,
K.Seibert,
P.C.Isakson,
W.C.Stallings.
Structural Basis For Selective Inhibition of Cyclooxygenase-2 By Anti-Inflammatory Agents. Nature V. 384 644 1996.
Page generated: Sat Dec 12 02:32:44 2020
ISSN: ISSN 0028-0836 PubMed: 8967954 DOI: 10.1038/384644A0 |
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