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PDB 6c3u-6e41 »
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Bromine in PDB 6ctx: Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Dctp Analogue
Enzymatic activity of Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Dctp Analogue
All present enzymatic activity of Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Dctp Analogue:
2.7.7.7;
2.7.7.7;
Protein crystallography data
The structure of Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Dctp Analogue, PDB code: 6ctx
was solved by
V.K.Batra,
S.H.Wilson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 31.79 / 2.02 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 50.815, 79.565, 55.502, 90.00, 107.78, 90.00 |
| R / Rfree (%) | 17.7 / 22.9 |
Other elements in 6ctx:
The structure of Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Dctp Analogue also contains other interesting chemical elements:
| Magnesium | (Mg) | 2 atoms |
| Chlorine | (Cl) | 1 atom |
| Sodium | (Na) | 3 atoms |
Bromine Binding Sites:
The binding sites of Bromine atom in the Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Dctp Analogue
(pdb code 6ctx). This binding sites where shown within
5.0 Angstroms radius around Bromine atom.
In total 2 binding sites of Bromine where determined in the Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Dctp Analogue, PDB code: 6ctx:
Jump to Bromine binding site number: 1; 2;
In total 2 binding sites of Bromine where determined in the Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Dctp Analogue, PDB code: 6ctx:
Jump to Bromine binding site number: 1; 2;
Bromine binding site 1 out of 2 in 6ctx
Go back to
Bromine Binding Sites List in 6ctx
Bromine binding site 1 out
of 2 in the Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Dctp Analogue
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 1 of Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Dctp Analogue within 5.0Å range:
|
Bromine binding site 2 out of 2 in 6ctx
Go back to
Bromine Binding Sites List in 6ctx
Bromine binding site 2 out
of 2 in the Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Dctp Analogue
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Bromine with other atoms in the Br binding
site number 2 of Ternary Complex Crystal Structure of Dna Polymerase Beta with A Dideoxy Terminated Primer with CBR2, Beta, Gamma Dctp Analogue within 5.0Å range:
|
Reference:
V.K.Batra,
K.Oertell,
W.A.Beard,
B.A.Kashemirov,
C.E.Mckenna,
M.F.Goodman,
S.H.Wilson.
Mapping Functional Substrate-Enzyme Interactions in the Pol Beta Active Site Through Chemical Biology: Structural Responses to Acidity Modification of Incoming Dntps. Biochemistry V. 57 3934 2018.
ISSN: ISSN 1520-4995
PubMed: 29874056
DOI: 10.1021/ACS.BIOCHEM.8B00418
Page generated: Thu Jul 11 01:34:50 2024
ISSN: ISSN 1520-4995
PubMed: 29874056
DOI: 10.1021/ACS.BIOCHEM.8B00418
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