Bromine in PDB 6erl: Quadruplex with Flipped Tetrad Formed By the C-Myc Promoter Sequence

The binding sites of Bromine atom in the Quadruplex with Flipped Tetrad Formed By the C-Myc Promoter Sequence (pdb code 6erl). This binding sites where shown within 5.0 Angstroms radius around Bromine atom.
In total 4 binding sites of Bromine where determined in the Quadruplex with Flipped Tetrad Formed By the C-Myc Promoter Sequence, PDB code: 6erl:
Jump to Bromine binding site number: 1; 2; 3; 4;

Bromine binding site 1 out of 4 in the Quadruplex with Flipped Tetrad Formed By the C-Myc Promoter Sequence


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 1 of Quadruplex with Flipped Tetrad Formed By the C-Myc Promoter Sequence within 5.0Å range: probe atom residue distance (Å) B Occ A:Br4 b:0.0 occ:1.00 BR A:BGM4 0.0 0.0 1.0 C8 A:BGM4 1.9 0.0 1.0 N7 A:BGM4 2.8 0.0 1.0 H1' A:BGM4 2.9 0.0 1.0 N9 A:BGM4 2.9 0.0 1.0 O4' A:DG5 3.4 0.0 1.0 C1' A:BGM4 3.4 0.0 1.0 H21 A:BGM8 3.8 0.0 1.0 H5' A:DG5 3.9 0.0 1.0 H4' A:DG5 4.0 0.0 1.0 C5 A:BGM4 4.0 0.0 1.0 C4 A:BGM4 4.0 0.0 1.0 H22 A:BGM8 4.1 0.0 1.0 H1' A:DG5 4.1 0.0 1.0 C1' A:DG5 4.2 0.0 1.0 C4' A:DG5 4.2 0.0 1.0 N2 A:BGM8 4.3 0.0 1.0 H2' A:BGM4 4.4 0.0 1.0 O4' A:BGM4 4.4 0.0 1.0 N9 A:DG5 4.4 0.0 1.0 C2' A:BGM4 4.5 0.0 1.0 C5' A:DG5 4.6 0.0 1.0 C4 A:DG5 4.7 0.0 1.0 H2 A:DA3 4.7 0.0 1.0 N3 A:DG5 4.8 0.0 1.0

Bromine binding site 2 out of 4 in the Quadruplex with Flipped Tetrad Formed By the C-Myc Promoter Sequence


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 2 of Quadruplex with Flipped Tetrad Formed By the C-Myc Promoter Sequence within 5.0Å range: probe atom residue distance (Å) B Occ A:Br8 b:0.0 occ:1.00 BR A:BGM8 0.0 0.0 1.0 C8 A:BGM8 1.9 0.0 1.0 N7 A:BGM8 2.8 0.0 1.0 H1' A:BGM8 2.9 0.0 1.0 N9 A:BGM8 2.9 0.0 1.0 H4' A:DA12 3.0 0.0 1.0 O4' A:DG9 3.4 0.0 1.0 C1' A:BGM8 3.4 0.0 1.0 H5' A:DG9 3.6 0.0 1.0 H21 A:BGM13 3.6 0.0 1.0 H2' A:BGM8 3.8 0.0 1.0 H22 A:BGM13 3.9 0.0 1.0 C5 A:BGM8 3.9 0.0 1.0 O4 A:DT1 4.0 0.0 1.0 C4' A:DA12 4.0 0.0 1.0 C4 A:BGM8 4.0 0.0 1.0 N2 A:BGM13 4.2 0.0 1.0 H5' A:DA12 4.2 0.0 1.0 C2' A:BGM8 4.2 0.0 1.0 C4' A:DG9 4.3 0.0 1.0 H5'' A:DA12 4.3 0.0 1.0 C1' A:DG9 4.4 0.0 1.0 N9 A:DG9 4.4 0.0 1.0 C5' A:DG9 4.4 0.0 1.0 H4' A:DG9 4.4 0.0 1.0 C5' A:DA12 4.5 0.0 1.0 O4' A:DA12 4.5 0.0 1.0 O4' A:BGM8 4.6 0.0 1.0 C4 A:DG9 4.6 0.0 1.0 H1' A:DG9 4.7 0.0 1.0 O3' A:DA12 4.8 0.0 1.0 H2'' A:BGM8 4.9 0.0 1.0 C8 A:DG9 4.9 0.0 1.0 N3 A:DG9 4.9 0.0 1.0

Bromine binding site 3 out of 4 in the Quadruplex with Flipped Tetrad Formed By the C-Myc Promoter Sequence


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 3 of Quadruplex with Flipped Tetrad Formed By the C-Myc Promoter Sequence within 5.0Å range: probe atom residue distance (Å) B Occ A:Br13 b:0.0 occ:1.00 BR A:BGM13 0.0 0.0 1.0 C8 A:BGM13 1.9 0.0 1.0 N7 A:BGM13 2.8 0.0 1.0 H1' A:BGM13 2.9 0.0 1.0 N9 A:BGM13 2.9 0.0 1.0 O4' A:DG14 3.4 0.0 1.0 C1' A:BGM13 3.4 0.0 1.0 H21 A:BGM17 3.8 0.0 1.0 H5' A:DG14 3.9 0.0 1.0 C5 A:BGM13 4.0 0.0 1.0 H4' A:DG14 4.0 0.0 1.0 C4 A:BGM13 4.0 0.0 1.0 H1' A:DG14 4.0 0.0 1.0 H22 A:BGM17 4.1 0.0 1.0 C1' A:DG14 4.1 0.0 1.0 C4' A:DG14 4.2 0.0 1.0 N2 A:BGM17 4.3 0.0 1.0 N9 A:DG14 4.4 0.0 1.0 H2' A:BGM13 4.4 0.0 1.0 O4' A:BGM13 4.5 0.0 1.0 C2' A:BGM13 4.5 0.0 1.0 C5' A:DG14 4.6 0.0 1.0 C4 A:DG14 4.7 0.0 1.0 N3 A:DG14 4.9 0.0 1.0

Bromine binding site 4 out of 4 in the Quadruplex with Flipped Tetrad Formed By the C-Myc Promoter Sequence


Mono view


Stereo pair view

A full contact list of Bromine with other atoms in the Br binding site number 4 of Quadruplex with Flipped Tetrad Formed By the C-Myc Promoter Sequence within 5.0Å range: probe atom residue distance (Å) B Occ A:Br17 b:0.0 occ:1.00 BR A:BGM17 0.0 0.0 1.0 C8 A:BGM17 1.9 0.0 1.0 N7 A:BGM17 2.8 0.0 1.0 H1' A:BGM17 2.9 0.0 1.0 N9 A:BGM17 2.9 0.0 1.0 C1' A:BGM17 3.4 0.0 1.0 O4' A:DG18 3.4 0.0 1.0 H21 A:BGM4 3.6 0.0 1.0 H2' A:BGM17 3.7 0.0 1.0 H22 A:BGM4 3.9 0.0 1.0 H5' A:DG18 3.9 0.0 1.0 C5 A:BGM17 4.0 0.0 1.0 C4 A:BGM17 4.0 0.0 1.0 C2' A:BGM17 4.1 0.0 1.0 N2 A:BGM4 4.2 0.0 1.0 N9 A:DG18 4.2 0.0 1.0 C4 A:DG18 4.2 0.0 1.0 N3 A:DG18 4.3 0.0 1.0 H2'' A:DA3 4.3 0.0 1.0 C1' A:DG18 4.3 0.0 1.0 H22 A:DG2 4.4 0.0 1.0 H21 A:DG2 4.4 0.0 1.0 C4' A:DG18 4.4 0.0 1.0 N2 A:DG2 4.5 0.0 1.0 H4' A:DG18 4.5 0.0 1.0 O4' A:BGM17 4.7 0.0 1.0 H1' A:DG18 4.7 0.0 1.0 C5' A:DG18 4.7 0.0 1.0 H2'' A:BGM17 4.8 0.0 1.0 C8 A:DG18 4.8 0.0 1.0 C5 A:DG18 4.8 0.0 1.0 H2' A:DA3 4.9 0.0 1.0 C2 A:DG18 4.9 0.0 1.0

B.Karg, K.Weisz. Loop Length Affects Syn-Anti Conformational Rearrangements in Parallel G-Quadruplexes. Chemistry 2018.
ISSN: ISSN 1521-3765
PubMed: 29756658
DOI: 10.1002/CHEM.201801851